Personalized therapy does not reduce hospitalization in chronic kidney disease
1. In this randomized controlled trial, algorithmic identification based on electronic health...
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chronic-disease
Gender is not a mediating factor in the relationship between pain and post traumatic stress disorder
1. Post-traumatic stress disorder (PTSD) symptoms were associated with higher levels of chronic...
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Lixisenatide as a treatment for early Parkinson’s disease progression
1. In this randomized controlled trial, lixisenatide reduced motor disability progression in...
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Podiatric care for diabetic patients is associated with reduced risk of major amputation and death
1. For diabetic patients undergoing hemodialysis, receiving foot and ankle care from a podiatrist...
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Chest radiograph deep-learning model for cardiac event risk estimation
1. In this retrospective study, the chest X-ray cardiovascular disease (CXR CVD)-risk model...
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Osteoporosis prevalence in patients undergoing peritoneal dialysis is not correlated with vitamin D levels
1. In patients undergoing peritoneal dialysis, osteoporosis is highly prevalent but does not...
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Intrathecal gene therapy as a treatment for giant axonal neuropathy
1. In this dose-escalation study, using intrathecal gene transfer with scAAV9/JeT-GAN demonstrated...
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Intravascular ultrasound-guided stent insertion improves outcomes in patients with acute coronary syndrome
1. Target-vessel failure was significantly lower in the ultrasound-guided group than the...
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Perioperative Nivolumab in Resectable Lung Cancer
1. The 18-month event-free survival in the perioperative nivolumab group was 70.2% vs 50.0% in the...
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Female physicians associated with improved inpatient mortality and readmission rates
1. In this observational study, inpatients treated by a female physician had lower 30-day...
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Genomic data optimizes hematopoietic stem-cell transplantation (HSCT) timing for myelodysplastic syndromes (MDS) and improves patient outcomes
1. A decision support system using the Molecular International Prognostic Scoring System (IPSS-M)...
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Ultra-processed food consumption increases all-cause mortality
1. Consumption of ultra-processed foods was associated with modestly higher all cause mortality,...
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Intra-articular platelet-rich plasma injection does not improve knee function following anterior cruciate ligament repair
1. At 12 months, patients with anterior cruciate ligament reconstruction randomized to receive...
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Positron emission tomography-guided treatment strategy may reduce need for chemotherapy for patients with HER2+ breast cancer
1. 3-year invasive disease-free survival among the PET-based treatment group was 94.8%. 2. There...
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Remote electronic patient reported outcomes may have limited feasibility in older patients with cancer
1. Among patients on anticancer treatment with malignancy who were 75 years of age or older, the...
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Capecitabine or XELOX did not appear to improve overall survival when compared to PF in patients with advanced Esophageal Squamous Cell Carcinoma
1. Although capecitabine or XELOX did not improve overall survival when compared to PF, efficacy...
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Trastuzumab Deruxtecan in Solid Tumours Harbouring HER2 Mutations
1. The objective response rate for trastuzumab deruxtecan was 29.4%. 2. Treatment-emergent adverse...
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Minimal Residual Disease negativity after Autologous Hematopoietic Cell Transplantation with lenalidomide maintenance predicts better long-term outcomes in myeloma
1. Achieving Minimal Residual Disease (MRD) negativity at baseline before lenalidomide...
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Promising results with new oncolytic virus targeted at advanced solid tumors
1. The use of recombinant L-IFN adenovirus in patients with recurrent or refractory advanced solid...
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Low lower-limb muscle mass index with weight-bearing activity increases incidence of osteoarthritis
1. Increased incidence of radiographic knee osteoarthritis was associated with high amounts of...
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