Vaccination leads to a small absolute risk for shoulder conditions
1. Based on the study, there is a small absolute risk for shoulder conditions after vaccination....
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chronic-disease
Baricitinib is superior to placebo for treatment of alopecia areata
1. Oral baricitinib is superior to placebo regarding hair regrowth at 36 weeks. 2. Oral...
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Higher-dose primaquine has higher efficacy in preventing relapse of Plasmodium vivax malaria
1. Compared to lower dose primaquine, higher dose primaquine had higher efficacy in preventing...
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Oral tebipenem pivoxil hydrobromide is effective in treatment of complicated urinary tract infection
1. Compared to intravenous ertapenem, oral tebipenem pivoxil hydrobromide was non-inferior in the...
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Rilzabrutinib demonstrates rapid and durable clinical activity for immune thrombocytopenia
1. Rilzabrutinib was active and 400mg twice daily was identified as the dose for further testing...
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Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015
1. Between 1998 to 2015, mortality rates for myocardial infarction, stroke, and pulmonary embolism...
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Elevated neutrophil-lymphocyte ratio associated with poor prognosis for head and neck cancer
1. This single-centred, observational cohort study demonstrated that among patients with head and...
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Prenatal exposure to maternal autoimmune diseases associated with increased risks of mental disorders in offspring
1. In utero exposure to any maternal autoimmune disease was associated with increased risks of...
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Radiofrequency renal denervation produces long-lasting reductions in blood pressure
1. The intervention group saw a 10 mmHg greater reduction in 24-h mean systolic blood pressure...
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Reduced bleeding risk with asundexian compared to apixaban in patients with atrial fibrillation
1. Asundexian 50 mg resulted in a lower rate of bleeding compared to apixaban 5 mg twice daily. 2....
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Exposure to hydraulic fracturing sites is associated with some adverse birth outcomes
1. In a large cohort comparing 35,000 pregnancies of women living near hydraulic fracturing sites...
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Testing for sexually transmitted infections is infrequent among high school students in the United States
1. In a 2019 national survey of 2501 high school students across the United States, only 20.4% of...
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Adjuvant chemotherapy associated with an improved overall survival for patients with locally advanced gastric cancer
1. In this retrospective cohort study, 462 patients with locally advanced gastric cancer...
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Daprodustat noninferior to darbepoetin alfa in the treatment of anemia in patients with chronic kidney disease on incident dialysis – the ASCEND-ID trial
1. This trial demonstrated noninferiority of daprodustat to darbepoetin alfa in the treatment of...
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Presence of second midwife during the second active stage of labour reduces the risk of severe perineal trauma
1. Severe perineal trauma occurred in 5.7% of patients with one midwife and 3.9% of patients with...
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Subcortical neurons associated with sleep disturbances in neurodegenerative disease
1. Greater number of neurons in the lateral hypothalamic area (LHA) and tuberomammillary nucleus...
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Glyburide non-inferior to insulin for perinatal outcomes in gestational diabetes
1. This population-based cohort study demonstrated that oral glyburide as first-line treatment for...
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Bone mineral density testing beneficial for older men receiving androgen deprivation therapy for localized or regional prostate cancer
1. Bone mineral density testing was associated with a significant decreased risk of developing...
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Oral gefapixant reduces frequency of refractory or unexplained chronic coughs
1. Gefapixant 45 mg twice a day showed significant reductions in chronic cough over 12-24 weeks...
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Barriers to medication access for opioid use disorder in adolescents and young adults
1. In this systematic review of 37 studies, multiple barriers were identified in accessing...
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