Elevated NT-proBNP as a cardiovascular disease risk equivalent
1. In this prospective cohort study, participants with elevated N-terminal pro-B-type natriuretic...
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chronic-disease
Fractional flow reserve guidance for percutaneous coronary intervention is similar to intravascular ultrasonography guidance
1. Fractional flow reserve (FFR) guidance for percutaneous coronary intervention (PCI) was...
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Bedaquiline-pretomanid-linezolid regimen is effective for treating drug-resistant tuberculosis
1. Four bedaquiline-pretomanid-linezolid treatment groups had a favorable outcome for the...
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Risk of gestational diabetes diagnosis significantly increased among individuals with high polygenic risk scores and low levels of physical activity
1. Patients with diabetes and high polygenic risk scores are at an increased risk of developing...
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Incidence of C. difficile infections decreasing in hospitalized children
1. In a very large retrospective cohort of hospitalized pediatric patients, the incidence of C....
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Dolutegravir associated with improved viral suppression in HIV-positive pregnant patients
1. Dolutegravir is associated with greater viral suppression at birth for human immunodeficiency...
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Adjuvant erlotinib increased overall survival when compared to chemotherapy in stage IIIA EGFR-mutant non-small cell lung cancer
1. Erlotinib showed an overall survival benefit and improved 5-year survival rates when compared...
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Sacituzumab govitecan may be an effective treatment for heavily pre-treated HR+/HER2- metastatic breast cancer.
1. Median progression-free survival was longer in the SG group than in the chemotherapy group. 2....
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Physical function as a predictor for cardiovascular disease risk in the elderly
1. A higher physical function among community-dwelling older adults was associated with a...
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Remote ischemic conditioning associated with better neurologic function in patients with acute moderate ischemic stroke – the RICAMIS trial
1. In this randomized clinical trial, among 1893 patients with acute moderate ischemic stroke,...
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Reinfection with hepatitis C virus is highest immediately after treatment in patients on opioid agonist therapy
1. Reinfection with hepatitis C virus (HCV) was highest in the first 24 weeks after treatment...
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Effectiveness of self-monitoring blood pressure program with smartphone application
1. A self-monitoring blood pressure (SMBP) program enhanced with smartphone patient engagement...
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The influence of body-mind-spirit interventions on well-being may be poorly understood
1. Few studies included all concepts of the Body-Mind-Spirit (BMS), including detailed...
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Youth-onset type 2 diabetes may have increased sharply during the COVID-19 pandemic
1. In a retrospective cohort of about 3,000 children and young adults, new diagnoses of type 2...
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Ublituximab lowers incidence of relapse and number of brain lesions in relapsing multiple sclerosis
1. Two randomized clinical trials showed that intravenous ublituximab reduced relapse rate and the...
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Olokizumab is noninferior to adalimumab for the treatment of rheumatoid arthritis
1. Olokizumab was superior to placebo in improving rheumatoid arthritis (RA) symptoms. 2....
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Childhood cash supplementation program may improve outcomes into adulthood
1. In this longitudinal cohort study assessing the benefits of a cash supplementation program in...
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Statin use provide effective primary prevention against cardiovascular disease in high-risk patients – US Preventive Services Task Force
1. Statin use in patients at increased risk of cardiovascular disease without prior history of...
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Mepolizumab reduced exacerbations in children with exacerbation-prone eosinophilic asthma
1. There was a 27% reduction of severe asthma exacerbations in children treated with mepolizumab...
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Mitapivat may improve anemia in adults with non-transfusion dependent α- and β-thalassemia
1. 80% of patients receiving mitapivat showed hemoglobin response at 12 weeks. 2. Markers of...
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