Neoadjuvant celmiplimab is associated with pathologic response in cutaneous squamous cell carcinoma
1. After neoadjuvant treatment with celmiplimab, half of the patients were found to have a...
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chronic-disease
Summary Elixhauser score interally validated for mortality prediction in older adults
1. The Summary Elixhauser (S-Elixhauser) comorbidity score is internally validated for predicting...
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Study reports improvement in pediatric liver transplant outcomes over past decades
1. In approximately 14,000 pediatric patients across Europe who received a liver transplant...
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Low prevalence of adrenal tumors in the general adult screening population
1. The prevalence of adrenal tumors in the general adult screening population is 1.4%. 2. The...
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Impact of ultrasonographic blind spots for early-stage hepatocellular carcinoma during surveillance
1. Hepatocellular carcinoma (HCC) tumours located in ultrasound (US) blind spots were associated...
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Altered carbohydrate and protein intake may affect sleep quality
1. In this systematic review, long-term increased carbohydrate intake improved rapid eye movement...
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Young children who experience eviction have increased health risks
1. In a retrospective cohort of young children in the United States, prior eviction was associated...
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Combination avelumab and axitinib treatment of advanced type B3 thymoma and thymic carcinoma is promising as second-line treatment after standard therapy.
1. Patients who had never previously received anti-angiogenesis treatments had longer...
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Risk of myopathy and myalgia among statin users may be small and clinically insignificant
1. 27.1% of patient in the statin group reported muscle pain and weakness compared to 26.6% in the...
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Sleep disorders are risk factors in the onset of depression
1. In this systematic review and meta-analysis, it was found that insomnia, hypersomnia,...
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Neighborhood disadvantage is associated with increased risk of psychiatric disorders in refugee children
1. In a retrospective study of refugee children in Denmark, there was a linear association...
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Antihypertensives reduce the rate of progressive aortic root dilation in Marfan syndrome
1. Compared to control, ARBs reduced the annual rate of increase of the aortic root Z score by...
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Nonpharmaceutical interventions increase sleep duration in children
1. In a systematic review and meta-analysis of 45 randomized controlled trials including healthy...
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Selective laser trabeculectomy offers long-term benefits over eye drops for glaucoma
1. In a randomized trial comparing selective laser trabeculectomy (SLT) to intraocular pressure...
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Polypill strategy reduces the risk of cardiovascular events after a myocardial infarction
1. A polypill consisting of aspirin, ramipril, and atorvastatin reduced the risk of major adverse...
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Wellness Check: Sleep
Sleep surgery for obstructive sleep apnea may decrease blood pressure 1. In this systematic review...
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Individuals with autoimmune diseases may have an increased risk for cardiovascular diseases
1. An increased incidence of new cardiovascular disease was seen in individuals with autoimmune...
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Artificial sweetener intake and association with cardiovascular disease risk
1. In a large French adult cohort, artificial sweetener intake was associated with increased risk...
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Rivaroxaban does not prevent cardiovascular events in rheumatic heart disease patients with atrial fibrillation
1. Rivaroxaban was not associated with a lower rate of cardiovascular events and death compared to...
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SGLT-2 inhibitors provide morbidity and mortality benefits for patients with heart failure
1. SGLT-2 inhibitors reduced time to first hospitalization and cardiovascular death among patients...
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