Serum interleukins may be elevated in patients with obsessive-compulsive disorder
1. Serum interleukin-1β (IL-1β) and interleukin-6 (IL-6) levels were higher in...
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chronic-disease
Comparison of hip fracture risk assessment tools for elderly patients
1. Femoral neck bone mineral density (FNBMD) alone discriminated 5-year hip fracture risk at least...
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Subcutaneous amivantamab with lazertinib is non-inferior to intravenous administration, with fewer adverse reactions
1. Subcutaneous amivantamab combined with lazertinib was non-inferior to intravenous amivantamab...
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Amivantamab and Lazertinib in Untreated EGFR-Mutated Advanced NSCLC
1. The progression-free survival between the amivantamab–lazertinib group (23.7 months) and the...
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Anti-CD38 monoclonal antibody improves platelet counts in immune thrombocytopenia
1. In this randomized controlled trial, CM313, an anti-CD38 monoclonal antibody therapy, was...
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APOE3 Christchurch heterozygosity may delay cognitive impairment in Alzheimer’s disease
1. Carriers of the E280A variant of presenilin 1 (PSEN1E280A) who were heterozygous for the...
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Daratumumab linked to improved progression-free survival and MRD-negativity in transplant-eligible myeloma patients
1. Daratumumab in combination with bortezomib, thalidomide, and dexamethasone (D-VTd) as induction...
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Circulating Tumor DNA-Guided De-Escalation Targeted Therapy for Advanced NSCLC
1. Patients with no biochemical or radiographic evidence of progressive disease had a median...
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Ticagrelor and aspiring dual antiplatelet therapy is favourable over monotherapy following coronary artery bypass
1. Dual antiplatelet therapy with ticagrelor and asprin led to a significantly lower risk of major...
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Heat-Induced 1.5°C Core Temperature Increase Doubles Myocardial Blood Flow in Healthy Individuals; Linked to Asymptomatic Myocardial Ischemia in CAD
1. In this randomized controlled trial, exposure to heat that increased core temperature by 1.5C...
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Early asthma and COPD intervention decreases healthcare utilization
1. In this randomized controlled trial, adults with undiagnosed asthma or chronic obstructive...
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#VisualAbstract: Neoadjuvant Nivolumab and Ipilimumab Improve Outcomes in Resectable Stage III Melanoma
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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Osimertinib significantly improved progression-free survival in patients with unresectable stage III non-small cell lung cancer
1. Treatment with osimertinib significantly improved progression-free survival, compared to...
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Neoadjuvant Immunotherapy in Mismatch Repair–Deficient Colon Cancer
1. No disease recurrences were observed during the median follow-up time of 26.2 months. 2....
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Quantifying the reduction of primary breast cancer associated with exercise
1. Across a follow-up period of approximately 5 years, there was a non-linear relationship between...
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Telephone coaching program may help patients achieve weight loss
1. The addition of 3 or 12 weeks of telephone coaching for individuals with suboptimal response in...
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Bimekizumab Safe and Effective for Moderate-To-Severe Hidradenitis Suppurativa Treatment
1. Significantly more patients in the bimekizumab group than placebo reported improved clinical...
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Long-term survival improved with use of tebentafusp for metastatic uveal melanoma
1. Across a median follow-up of 48.5 months, usage of tebentafusp for patients with metastatic...
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Gene Editing Improves Photoreceptor Function in Centrosomal Protein 290-Associated Retinal Degeneration
1. In this randomized controlled trial, among patients with centrosomal protein 290...
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Olezarsen effectively lowers triglycerides in patients with familial chylomicronemia syndrome
1. In this randomized controlled trial, 80 mg of olezarsen, but not 50 mg, significantly reduced...
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