Cisplatin with Veliparib in BRCA Stratified Metastatic Triple-Negative Breast Cancer
1. There was some progression-free survival benefit in adding veliparib to cisplatin in patients...
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chronic-disease
Physical activity may be helpful in treating depressive symptoms in children and adolescents
1. In a systematic review and meta-analysis, physical activity interventions were shown to...
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Web-based self-treatment may be an effective strategy in the management of benign paroxysmal positional vertigo
1. 85% of individuals randomized to undergo treatment with a web-based self-directed regimen were...
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Anterior knee pain following ACL reconstruction
1. Anterior knee pain (AKP) is a potential complication of ACL Reconstruction (ACLR) with...
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Ecopipam reduces tics in children with Tourette syndrome
1. In a phase 2 trial of patients with Tourette syndrome, ecopipam, a selective dopamine receptor...
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Post-acute care program for frail geriatric patients associated with better post-discharge outcomes
1. Frail, elderly patients participating in a post-acute care (PAC) program for more than 2 weeks...
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Chronic pain conditions associated with increased risk of later suicidal behaviour
1. Experiencing general chronic pain or somatic chronic pain are associated with increased risk of...
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Clinical decision-making strategy improves acute heart failure outcomes
1. A hospital-based strategy to support clinical decision-making and rapid follow-up resulted in a...
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Frail patients with acute decompensated heart failure may benefit from physical rehabilitation intervention
1. Patients with acute heart failure who were more frail at baseline derived greater benefits from...
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Early-life body size not an independent risk factor for colorectal cancer
1. Greater early-life body size is not an independent risk factor for colorectal cancer (aside...
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Low-carbohydrate, high-fat diet improves glycemic control in type 2 diabetic patients
1. A low-carbohydrate high-fat (LCHF) diet improved glycemic and weight control in patients with...
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Lecanemab may slow cognitive decline in early Alzheimer’s disease
1. Lecanemab was associated with reduced amyloid markers in early Alzheimer’s disease as compared...
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DART improves treatment decision-making for patients with chronic kidney disease
1. Patients with chronic kidney disease (CKD) who used Decision-Aid for Renal Therapy (DART)...
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Intensive outpatient prolonged exposure effective for combat related posttraumatic stress disorder
1. For military personnel and veterans with PTSD, intensive outpatient prolonged exposure (IOP-PE)...
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Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer
1. In patients with KRAS p.G12C mutated pancreatic cancer, 21% had a partial response, and 0% had...
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Dupilumab improves symptoms and increases remission rates in eosinophilic esophagitis
1. Weekly dupilumab resulted in a significantly increased rate of histologic remission as compared...
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Significant paternal symptoms of depression and trauma following poor fetal, neonatal, and maternal outcomes
1. High paternal rates of distress seen in fathers exposed to poor fetal, neonatal and maternal...
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Christian Orthodox Church fasting may improve metabolic syndrome risk factors
1. In this scoping review, Christian Orthodox Church (COC) fasters had healthier blood lipid...
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Chlorthalidone is not superior to hydrochlorothiazide in preventing hypertension-related cardiovascular events
1. Patients with hypertension who received chlorthalidone did not have a lower occurrence of...
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Oral BPaLM regimen is noninferior to standard of care for rifampin-resistant tuberculosis
1. A 24-week regimen of bedaquiline, pretomanid, linezolid, and moxifloxacin (BPaLM) resulted in...
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