Baxdrostat reduces blood pressure in previously treatment-resistant hypertension
1. Compared to placebo, baxdrostat showed a dose-dependent reduction in blood pressure in patients...
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chronic-disease
Study details side effects of alpha-2-adrenergic agonists for treating ADHD in preschool children
1. In a retrospective cohort study, the use of alpha-2-adrenergic agonists to treat...
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Machine renal perfusion reduces delayed graft function after transplantation
1. In this randomized controlled trial, machine perfusion of the kidney reduced delayed graft...
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Momelotinib reduces symptom burden compared to danazol in patients with myelofibrosis
1. After a 24-week treatment period, a significantly greater proportion of patients randomized to...
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Low-dose pirfenidone may be noninferior to standard dosing in patients with idiopathic pulmonary fibrosis
1. For patients with idiopathic pulmonary fibrosis (IPF), there was no difference in pulmonary...
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Former professional football players may be at greater risk of chronic disease
1. In this retrospective cohort study, there was an increased prevalence of age-, race-, and body...
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Abuse during childhood and young adulthood is linked to welfare receipt
1. Experiencing either physical abuse alone or both physical and sexual abuse before the age of 18...
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Moderately accelerated cardiac pacing may be beneficial in patients with heart failure with preserved ejection fraction
1. Quality of life at one year was improved in patients with heart failure with preserved ejection...
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Exercise may be as effective as pharmacotherapy in managing osteoarthritis pain
1. In this network meta-analysis, there was no difference between exercise, oral non-steroidal...
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Age-related macular degeneration may be associated with depression risk
1. In a large population-based cohort, age-related macular degeneration (AMD) diagnosis was...
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Food hardship relief is associated with fewer pediatric emergency department visits
1. Supplemental Nutrition Assistance Program (SNAP) participation is associated with decreased...
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Cystatin C-based equation without race or sex improves accuracy of GFR estimation
1. In this cross-sectional study, serum cystatin C levels were similar in both Black and White...
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High-dose exercise therapy is not superior to low-dose exercise therapy for knee osteoarthritis
1. In this randomized control trial of knee osteoarthritis patients, there was no significant...
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Mavacamten associated with improvement in submaximal exertional tolerance: A secondary analysis of the EXPLORER-HCM randomized trial
1. In the EXPLORER-HCM trial, among 251 included patients, there were significant improvements...
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Efanesoctocog alfa is efficacious in treating severe hemophilia A
1. Efanesoctocog alfa was superior to prestudy factor VIII prophylaxis in preventing bleeding in...
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Risk of hydroxychloroquine retinopathy increases with longer use and higher dosage
1. In this retrospective cohort study, the incidence of hydroxychloroquine retinopathy was 2.5% at...
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Adjuvant S-1 increases short-term survival in patients with resected biliary tract cancer
1. Patients who received adjuvant S-1 had prolonged overall survival and relapse-free survival...
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Rocatinlimab may be effective in the treatment of moderate-to-severe atopic dermatitis
1. At week 16, all rocatinlimab groups reported significant improvements in eczema severity. 2....
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Epstein-Barr viral load monitoring reduces risk of post-liver transplant lymphoproliferative disease
1. Epstein-Barr viral load monitoring was associated with reduced post-liver transplant...
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Bisphosphonates, denosumab, abaloparatide, teriparatide, and romosozumab reduce postmenopausal fracture risk
1. Bisphosphonates, denosumab, abaloparatide, teriparatide, and romosozumab use are associated...
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