Pituitary microadenomas exhibit slow growth and may require less frequent MRI surveillance
1. In this retrospective cohort study, two-thirds of incidental pituitary microadenomas remained...
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chronic-disease
Combination therapy with alisterib and fulvestrant may be clinically advantageous in the treatment of endocrine-resistant advanced breast cancer
1. Compared to alisertib alone, adding alisertib to fulvestrant did not increase objective tumour...
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Paid-sick-leave mandates contribute to increased cancer screening in the United States
1. Mandated and available paid-sick-leave resulted in increased colorectal and breast cancer...
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Neoadjuvant–Adjuvant vs. Adjuvant-Only Pembrolizumab in Advanced Melanoma
1. Event-free survival at 2 years was longer in the neoadjuvant-adjuvant group vs the...
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School nutritional quality programs associated with lower BMI in children
1. In a retrospective cohort study, the implementation of policies to strengthen nutritional...
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Endovascular ultrasound renal denervation associated with lower ambulatory systolic blood pressure in patients with hypertension – The RADIANCE II randomized clinical trial
1. In this sham-controlled, randomized clinical trial, among 224 patients with hypertension,...
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Ultrasound renal denervation associated with reduced blood pressure in the RADIANCE II, RADIANCE-HTN SOLO, and RADIANCE-HTN TRIO trials – A pooled analysis
1. In this patient-level pooled analysis of 3 randomized clinical trials, among 506 patients with...
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Ultrasound renal denervation associated with reduced blood pressure in the RADIANCE II, RADIANCE-HTN SOLO, and RADIANCE-HTN TRIO trials – A pooled analysis
1. In this patient-level pooled analysis of 3 randomized clinical trials, among 506 patients with...
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The emergence of visual artistic creativity in frontotemporal dementia: a case-control study
1. This case-control study of 689 patients with frontotemporal dementia demonstrated that visual...
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Intravenous tenecteplase non-inferior to alteplase for patients with acute ischemic strokes
1. A similar proportion of patients in the alteplase group reported a modified Rankin Scale score...
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Poor sleep associated with lower cardiovascular disease-free life expectancy
1. Self-reported and clinically diagnosed poor sleep are associated with lower cardiovascular...
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Treat-to-target approach non-inferior to high-dose statin therapy in patients with coronary artery disease
1. Patients who received statin therapy using a treat-to-target approach (targeting...
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ImpresU effective in reducing antibiotic prescribing for frail elderly for urinary tract infections
1. Antibiotic stewardship interventions safely reduced antibiotic prescribing for frail older...
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Differences in cardiovascular health between sexual minorities and heterosexual adults
1. Bisexual women tended to have worse health profiles, including body mass index and overall...
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Higher protein doses do not improve outcomes in mechanically ventilated patients with high nutritional risk
1. Time-to-discharge-alive from the hospital was similar among both high- and regular-protein...
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Cold snare polypectomy associated with fewer complications than hot snare polypectomy
1. In this randomized controlled trial, cold snare polypectomy (CSP) reduced the risk of delayed...
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Valactogene roxaparvovec for hemophilia A demonstrates factor VIII durability for two years
1. At least two years after gene transfer, valoctocogene roxaparvovec demonstrated durability of...
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Implantable loop recorder screening for atrial fibrillation associated with increased diagnosis of bradyarrhythmia and pacemaker implantations – A post-hoc analysis of the LOOP randomized clinical trial
1. In this post hoc analysis of the LOOP randomized clinical trial, among 6004 participants older...
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Screen time and sedentary lifestyle associated with increased obesity rates among adolescents
1. In an American cohort of adolescents, a combination of high screen time and low physical...
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Days alive out of hospital after ventricular assist device implantation vary with comorbidity status
1. This cohort study showed significant variability in days alive out of hospital (DAOH) within...
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