Patients with early pregnancy loss less likely to receive active management in the emergency department
1. Among patients aged 15-49 with early pregnancy loss, those diagnosed in the emergency...
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chronic-disease
Adenoma detection rate is inversely associated with post-colonoscopy colorectal cancer risk
1. In this prospective cohort study, the adenoma detection rate (ADR) was inversely associated...
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Post-traumatic stress disorder and sleep disorders may exhibit a bi-directional relationship in U.S military members
1. In this prospective cohort study, military members who reported a post-traumatic stress...
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Symptom and viral relapse more common in COVID-19 patients without antiviral treatment
1. In this retrospective analysis, symptom and viral rebound occurred in almost one-third of...
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Specific histopathologic renal lesions may be associated with increased risk of cardiovascular disease
1. Risk of major adverse cardiac events increased amongst patients with a specific glomerular...
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Nivolumab plus ipilimumab does not improve survival in post-nephrectomy patients with renal cell carcinoma
1. Disease-free survival in the placebo group was 50.7 months and was never reached in the...
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Synergistic interaction between risk burden and genetics for atrial fibrillation development
1. In a large prospective study, risk burden and genetic predisposition acted synergistically to...
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Dementia is associated with high rates of sleep-related breathing disorders
1. In this meta-analysis, it was found that the pooled prevalence of sleep-related breathing...
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Active monitoring, prostatectomy, and radiotherapy as treatment options for localized prostate cancer result in similar prostate-cancer-mortality
1. Localized prostate cancer mortality remains similar between groups receiving prostatectomy,...
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Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors
1. There is a 71% lower risk of disease progression or death in the nirogacestat group than in the...
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Exercise and caloric restriction reduce visceral fat in overweight adults
1. In this systematic review and meta-analysis, both exercise and caloric restriction were...
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Sotorasib superior to docetaxel for treatment of KRASG12C-positive non-small-cell lung cancer
1. Patients allocated to the sotorasib group reported increased progression-free survival compared...
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Age and genetics as risk factors for the development of atrial fibrillation
1. In this prospective cohort study, age was found to be the most prominent risk factor for the...
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Etranacogene dezaparvovec gene therapy reduces bleeding in severe hemophilia B
1. Etranacogene dezaparvovec gene therapy was more effective than prophylactic factor IX infusion...
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Sodium bicarbonate does not prevent declining kidney function in kidney transplant recipients
1. The mean eGFR slope was comparable among patients allocated to sodium bicarbonate and placebo...
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Ultrasound ablation of globus pallidus reduces Parkinson’s disease motor symptoms
1. In this randomized controlled trial, ultrasound ablation of the globus pallidus was associated...
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Sodium-glucose cotransporter-2 inhibitors are of intermediate or low economic value in the treatment of heart failure with preserved ejection fraction
1. Sodium-glucose cotransporter-2 inhibitors (SGLT2-I) in combination with standard of care were...
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Secukinumab reduces symptoms of moderate-to-severe hidradenitis suppurativa
1. Patients receiving secukinumab every 2-weeks showed superior clinical response rates compared...
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Black patients with pulmonary fibrosis may have worse outcomes compared to other populations
1. In this retrospective cohort study, Black patients with pulmonary fibrosis (PF) were found to...
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Bedaquiline-linezolid regimen noninferior to standard treatment for tuberculosis
1. In this randomized control trial, an eight-week bedaquiline-linezolid regimen was noninferior...
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