ECZTRA 6 Phase 3 Randomized Trial Supports Tralokinumab for Adolescent Moderate-to-Severe Atopic Dermatitis
1. Interleukin-13 targeted treatment with tralokinumab was effective and well-tolerated for...
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chronic-disease
C-reactive protein may have superior prognostic value compared to low-density lipoprotein cholesterol for patients on statin therapy
1. High-sensitivity C-reactive protein increased the risk of all-cause mortality by two- to...
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Maternal lithium exposure in drinking water may increase risk of autism in offspring
1. In a population-based case-control study in Denmark, maternal exposure to lithium in water...
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Migraines associated with increased iron deposition in various brain structures
1. Patients with migraines had increased iron deposition in the putamen, caudate, and nucleus...
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Intradialytic exercise may improve patient survival rates in patients receiving hemodialysis
1. Intradialytic exercise for a minimum of 60 minutes during thrice weekly dialysis sessions...
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C-reactive protein may have superior prognostic value compared to LDL-cholesterol for patients on statin therapy
1. High-sensitivity CRP increased the risk of all-cause mortality by two- to three-fold among all...
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Relationship between mean blood pressure and clinical outcome after acute ischemic stroke
1. This retrospective cohort study found a U-shaped relationship between mean SBP and 3-month...
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Yoga helps alleviate symptoms of mild to moderate asthma in adults
1. In this meta-analysis, asthma patients who used yoga breathing exercises reported better...
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Early antibiotics in noncritical premature infants without clear infection linked to adverse outcomes
1. In a prospective cohort study, early antibiotic use in preterm, non-critical infants without a...
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Tislelizumab for advanced esophageal squamous cell carcinoma
1. Median overall survival was 17.2 months in the tislelizumab group versus 10.6 months in the...
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Previously treated advanced endometrial cancer treated with lenvatinib plus pembrolizumab results in greater survival than chemotherapy alone
1. Overall survival is longer for patients receiving a combination of lenvatinib plus...
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Denosumab for osteoporosis is associated with reduced diabetes risk compared to bisphosphonates
1. In a cohort of adults with osteoporosis, the use of denosumab was linked to a reduced risk of...
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Nut consumption may be inversely associated with frailty in older women
1. In this prospective cohort study, increased consumption of nuts was associated with a lower...
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Video decision support tool improves knowledge in Black implantable cardioverter-defibrillator candidates
1. In this randomized controlled trial, a video decision support tool (VIVID) increased knowledge...
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Immediate revascularization reduces myocardial infarction rates compared to staged revascularization in multivessel coronary disease
1. The immediate revascularization group met the noninferiority criteria for the primary composite...
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Reversion from prediabetes to normoglycemia only reduces all-cause mortality if physical activity increases
1. In a cohort of patients with prediabetes, reversion to normoglycemia did not reduce the risk of...
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Carbohydrate quantity and quality may influence plasma concentrations of some saturated fatty acids
1. In this randomized controlled trial, carbohydrate quantity and quality did not significantly...
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Self-reported functional impairment and frailty improve the prediction of healthcare expenditures
1. In this retrospective cohort study, the inclusion of functional impairment and phenotypic...
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Etrasimod improves clinical remission rates in patients with moderate-severe ulcerative colitis
1. In both ELEVATE UC 12 and ELEVATE UC 52, significantly greater patients in the etrasimod group...
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Yogurt intake may be associated with a lower risk of obesity during the menopausal transition
1. In this prospective cohort study, higher yogurt intake was associated with lower weight gain...
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