Orexin receptor 2 agonist reduces symptoms of narcolepsy type 1
Bookmark1. In this randomized controlled trial, an oral orexin receptor 2 (OX2R) agonist (TAK-994)...
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chronic-disease
Breast cancer screening discrepancies in different countries associated with different outcomes
Bookmark1. In Brasil, Russia, India, China, and South Africa, the availability of breast cancer...
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Mediterranean diet or mindfulness-based stress reduction during pregnancy may improve child neurodevelopment outcomes
Bookmark1. The offspring of individuals consuming a Mediterranean diet or engaging in a...
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Identification of placenta-brain axis genes associated with neurodevelopmental delay in moderate and late preterm children
Bookmark1. This analysis of a prospective cohort of moderate and late preterm (MLPT) children...
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Risk of persistent opioid use postpartum is overall equivocal for patients prescribed oxycodone versus codeine
Bookmark1. For postpartum pain management, there is no overall increased risk of persistent opioid...
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Survivors of childhood cancer are less active than their peers
Bookmark1. In a cross-sectional study, adolescent survivors of childhood cancers were more...
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Lisocabtagene maraleucel may induce remission in relapsed chronic lymphocytic leukemia (CLL)
Bookmark1. Complete response or remission was reported in 18% of patients who received a single...
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Many exercise modalities are effective treatments for hypertension
Bookmark1. In this systematic review and network meta-analysis, aerobic exercise training, dynamic...
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Once-weekly tirzepatide significantly improves weight and glycemic control in patients with with obesity and type 2 diabetes
Bookmark1. Body weight reduction at week 72 was significantly greater with tirzepatide versus...
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Dietary patterns may have effects on outcomes of assisted reproductive technologies
Bookmark1. For women with infertility on assisted reproductive technologies (ART), higher...
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Gene therapy improves bilirubin levels in Crigler-Najjar syndrome
Bookmark1. In this randomized controlled trial, a high dose of GNT0003 gene therapy was associated...
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Transcranial direct current stimulation does not improve outcomes for major depressive disorder
Bookmark1. Mean MADRS change at week 6 was -8.2 in the active tDCS group versus -8.0 in the sham...
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MIND diet does not prevent cognitive decline as compared to caloric restriction
Bookmark1. In this randomized controlled trial, there were no significant differences in the...
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Cancer mortality after low dose exposure to ionising radiation in workers
Bookmark1. The risk of mortality from solid cancer, lagged by 10 years, is estimated to be...
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Inappropriate hospital admission as a risk factor for the subsequent development of adverse events
Bookmark1. Patients with inappropriate hospital admission (IHA) experience twice more adverse...
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Retatrutide associated with improved glycemic control and bodyweight reduction in type 2 diabetes
Bookmark1. HbA1c and bodyweight reduction were greater in the retatrutide group compared to...
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Short sleep duration may be associated with the presence of dental caries
Bookmark1. In this cross-sectional study, there was a negative association between sleep duration...
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Endocrine therapy and breast-conserving surgical management without follow-up radiotherapy is safe in low-risk, luminal A subtype breast cancer
Bookmark1. 5-year recurrence incidence was 2.5% at follow-up. 2. Overall survival at 5 years...
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Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma
Bookmark1. Median progression-free survival was shown to be 27.7 months in the vorasidenib group...
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Pyrotinib plus capecitabine for trastuzumab-resistant, HER2-positive advanced breast cancer (PICTURE)
Bookmark1. This phase 2, single-arm, multicenter trial found that in HER2-positive breast cancer...
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