Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases
Bookmark1. The hazard ratio of skeletal-related events in patients treated with radiation compared...
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chronic-disease
Omission of axilla surgery is non-inferior to sentinel lymph node biopsy in female patients with small breast cancers and clinically negative axillary lymph nodes
Bookmark1. 5-year distant disease-free survival was comparable between both groups. 2. 5-year...
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Glucagon-like peptide-1 receptor agonists exhibit weight loss effects in non-diabetic patients with obesity
Bookmark1. This systematic review found that non-diabetic patients with obesity who received...
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Budesonide may be effective for slowing renal function decline in patients with IgA nephropathy
Bookmark1. Reduction in time-weighted glomerular filtration rate (GFR) decline was significantly...
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Intravenous dihydroergotamine safe for refractory chronic migraine
Bookmark1. Intravenous dihydroergotamine (DHE) was found in this retrospective study to be an...
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Immunotherapy plus stereotactic radiotherapy improves outcomes in early-stage lung cancer
Bookmark1. 4-year event-free survival was significantly greater in I-SABR (77%) versus SABR alone...
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Severe premenstrual disorder may increase risk of early onset perimenopausal symptoms
Bookmark1. This prospective study found that women with severe premenstrual disorders (PMDs) were...
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Tumor Treating Fields vs Standard Therapy in Treatment-Resistant Metastatic NSCLC
Bookmark1. The median OS was 13.2 months with TTFields arm vs 9.9 months with standard arm, with...
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Cognitive behavioural therapy effective for fibromyalgia pain
Bookmark1. This randomized controlled trial found that an 8-week cognitive behavioural therapy...
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Obstructive sleep apnea and vitamin D deficiency are closely linked
Bookmark1. In this systematic review and meta-analysis, patients with obstructive sleep apnea...
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Cetuximab maintenance therapy may be effective for RAS Wild-type metastatic colorectal cancer
Bookmark1. This phase 2 randomized clinical trial found that patients with metastatic colorectal...
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Evening chronotype in middle-aged nurses is associated with an increased diabetes risk
Bookmark1. In this prospective cohort study, middle-aged nurses with an evening chronotype were...
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Adjuvant nivolumab may be promising for treatment of completely resected Merkel cell carcinoma
Bookmark1. Disease-free survival at 24 months was 84% in the nivolumab group compared to 73% in...
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Non-erosive gastro-oesophageal reflux disease not associated with increased incidence of oesophageal adenocarcinoma
Bookmark1. Patients with non-erosive gastro-esophageal reflux disease (GERD) do not have an...
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Pegozafermin associated with improved outcomes in nonalcoholic steatohepatitis
Bookmark1. In this randomized controlled trial, treatment with pegozafermin improved fibrosis in...
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Atogepant may be safe and effective for prevention of chronic migraines
Bookmark1. Monthly migraine days were significantly reduced in atogepant 30 mg twice daily and...
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Mortality risk higher after the first occurrence of osteoporotic vertebral compression fractures
Bookmark1. Patients with a new diagnosis of osteoporotic vertebral compression fracture (OVCF) are...
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Low achievement of guideline-recommended diabetes targets in Chinese adults
1. In this cross-sectional study, the proportion of Chinese adults with self-reported type 2...
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High-dose oral semaglutide effectively glycemic control in patients with type 2 diabetes mellitus
Bookmark1. HbA1c reduction was dose-dependent in the semaglutide group with the greatest change...
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Combined digital intervention may be effective for osteoarthritis pain
Bookmark1. Following total knee replacement (TKR) for osteoarthritis, patients randomized to a...
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