Maintenance Olaparib Rechallenge in Platinum-Sensitive Relapsed Ovarian Cancer
Bookmark1. Median PFS was improved in the olaparib arm vs placebo, with an HR 0.57 in the BRCAm...
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chronic-disease
Adenocarcinoma is the most prevalent lung cancer subtype and has a greater incidence rate in males than females
Bookmark1. The second greatest burden of lung cancer worldwide is attributed to squamous cell...
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Fotagliptin monotherapy with alogliptin may be effective for uncontrolled type 2 diabetes
Bookmark1. Fotagliptin, a novel dipeptidyl peptidase-4 inhibitor (DPP4-i), was found to be...
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Long-term heat exposure associated with severe maternal morbidity
Bookmark1. This retrospective cohort of singleton pregnancies found that severe maternal morbidity...
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Edoxaban does not improve outcomes in patients with atrial high-rate episodes
Bookmark1. In this randomized controlled trial, edoxaban did not significantly reduce the...
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Sodium-glucose cotransporter-2 inhibitors may decrease incidence of recurrent gout flares
Bookmark1. Over a one-year period, the incidence of recurrent gout flares in patients with gout...
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Ferric carboxymaltose does not improve heart failure with iron deficiency
Bookmark1. In this randomized controlled trial, ferric carboxymaltose was not superior to placebo...
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Camrelizumab plus rivoceranib superior to sorafenib for treatment of unresectable hepatocellular carcinoma
Bookmark1. Patients in the camrelizumab-rivoceranib group reported significantly greater...
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Adjuvant everolimus does not improve survival for patients with resected renal cell carcinoma
Bookmark1. Recurrence-free survival was significantly different between the adjuvant everolimus...
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Atezolizumab, Vemurafenib, and Cobimetinib in Melanoma With CNS Metastases
Bookmark1. Intracranial objective response rate was 42% in the BRAF V600 mutation-positive cohort...
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Computer-aided detection does not improve neoplasm detection with colonoscopy
Bookmark1. The GI-Genius neural network system did not improve the rate of detecting advanced...
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Younger onset of non-alcoholic fatty liver disease associated with greater cancer risk
Bookmark1. In this case-control study, younger age of onset of non-alcoholic fatty liver disease...
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Bundled parenting and nutrition outreach program may positively influence the developmental and nutritional outcomes of siblings of targeted children
Bookmark1. Siblings of children receiving bundled parenting and nutrition intervention had better...
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Complete revascularization reduces mortality in older adults with myocardial infarction
Bookmark1. In this randomized controlled trial, complete revascularization reduced the risk of...
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Nurse-delivered sleep restriction therapy effective for treatment of chronic insomnia
Bookmark1. Sleep restriction therapy was superior to sleep hygiene for the management of chronic...
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Association between changes in carbohydrate intake and long term weight changes
Bookmark1. In this prospective cohort study, the types of carbohydrates consumed were associated...
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Increased consumption of ultra-processed foods may be associated with higher mortality in diabetic patients
Bookmark1. In this prospective cohort study, greater ultra-processed food intake was associated...
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Intravenous thrombolysis plus endovascular treatment may be more efficacious for acute ischemic stroke
Bookmark1. The 90-day modified Ranking Scale score was comparable for patients in intravenous...
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Pilot program of chronic hepatitis B treatment in Ethiopia
Bookmark1. In this pilot program conducted in Ethiopia, researchers demonstrated the long-term...
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Supplementation with γ-aminobutyric acid does not improve glucose control in patients with prediabetes
Bookmark1. In this randomized controlled trial, long-term γ-aminobutyric acid (GABA)...
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