Sacituzumab govitecan shows survival benefit in endocrine-resistant hormone-positive metastatic breast cancer
Bookmark1. Median overall survival increased by 3.2 months in the sacituzumab govitecan group...
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chronic-disease
Spiritual intelligence may be associated with self-management of type 1 diabetes
Bookmark1. In this cross-sectional study, spiritual intelligence was a significant predictor of...
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Avacincaptad pegol reduces the rate of age-related macular degeneration in geographic atrophy
Bookmark1. Avacincaptad pegol significantly slowed geographic atrophy over 12 months. 2. Exudative...
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Factors important for health-related quality of life in men and women
Bookmark1. This cross-sectional study found that physical activity, employment, pain, and sense of...
Read MoreSelpercatinib vs Chemotherapy and Pembrolizumab in RET Positive NSCLC
Bookmark1. The progression-free survival was 24.8 months in the selpercatinib group vs 11.2 months in the control group (chemotherapy ± pembrolizumab), with an HR of 0.46. 2. Grade ≥3 adverse events occurred in 70% vs 57%...
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Extracorporeal membrane oxygenation increases bleeding risk in patients with cardiogenic shock
Bookmark1. 30-day mortality was comparable among patients on VA-ECMO and medical therapy alone. 2....
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Nasal ventilation function is associated with the etiology and treatment of obstructive sleep apnea syndrome in children
Bookmark1. This randomized controlled trial found that children with obstructive sleep apnea...
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Amivantamab plus Chemotherapy in NSCLC with EGFR Exon 20 Insertions
Bookmark1. Median progression-free survival was 11.4 months in the amivantamab–chemotherapy group...
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Treatment of metastatic uveal melanoma with tebentafusp provides greater overall survival and progression-free survival as compared to standard treatment options
Bookmark1. Median overall survival and progression-free survival were greater in the tebentafusp...
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Higher intensity exercise associated with greater decrease in nonalcoholic fatty liver disease risk
Bookmark1. This analysis of a population-based cohort found that those who engaged in high and...
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Parental hesitancy towards vaccines unchanged after COVID Pandemic
Bookmark1. In surveyed sample, parental hesitancy towards routine vaccination during the pandemic...
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Caregivers name potential benefits and harms and availability of reliable information as main factors influencing their decision to vaccinate their child against COVID-19
Bookmark1. Nearly all participating caregivers listed the following as important influences on...
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COVID Pandemic did not increase parental hesitancy towards childhood vaccines
Bookmark1. In surveyed sample, parental hesitancy towards routine vaccination during the pandemic...
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Berzosertib Plus Topotecan vs Topotecan Alone in Relapsed Small Cell Lung Cancer
Bookmark1 .The progression-free survival in berzosertib with topotecan vs topotecan alone was not...
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Health insurance type associated with differences in infant mortality rates in the US
Bookmark1. In this cohort study, patients with Medicaid insurance coverage had higher rates of...
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Multicancer early detection blood tests show promise but warrant further clinical evaluation
Bookmark1. One-third of patients with a cancer signal were correctly diagnosed to have cancer. 2....
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Early versus delayed antihypertensive treatment in patients with acute ischaemic stroke
Bookmark1. In this randomized controlled trial, early compared to late blood pressure management...
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Adaptive resynchronization shows no benefit over conventional biventricular resynchronization in patients with heart failure
Bookmark1. All-cause mortality after 5 years was similar for patients in the adaptive and...
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Live viral vaccines safe for pediatric solid organ transplant recipients
Bookmark1. This cohort study of pediatric solid organ transplant (SOT) patients found that the...
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Spiritual well-being may be associated with improvements in pain intensity and catastrophizing in patients with chronic pain
Bookmark1. In this cross-sectional study, there was a high-level negative correlation between...
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