Five modifiable risk factors contribute to cardiovascular disease and mortality
1. In this retrospective cohort study, five risk factors (body mass index, systolic blood...
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chronic-disease
Methotrexate alleviates pain among patients with hand osteoarthritis and concurrent synovitis
1. Methotrexate 20 mg once weekly resulted in significant pain reduction among patients with hand...
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Low-dose amitriptyline effective and well-tolerated for management of irritable bowel syndrome
1. Low-dose amitriptyline was associated with a marked decrease in IBS-SSS score at 6 months...
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Hypertonic saline stimulation is superior to arginine for diagnosing AVP deficiency
1. In this prospective cohort study, hypertonic saline-stimulated copeptin was more accurate in...
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Early endovascular thrombectomy improves functional outcomes in large infarct ischaemic stroke
1. Patients in the thrombectomy group reported significantly greater improvement, with lower...
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Thalidomide reduces recurrent bleeding from small-intestinal angiodysplasia
1. In this randomized controlled trial, thalidomide resulted in a dose-dependent reduction in...
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Methotrexate Reduces Pain in Inflammatory Hand Osteoarthritis
1. Methotrexate 20 mg once weekly resulted in significant pain reduction among patients with hand...
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Inflammatory tongue conditions associated with increased risk of oral tongue cancer
1. In this case-control study, those with tongue cancer were found to have ten-fold increases in...
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OCT-guided PCI results in larger minimum stent area than angiography-guided PCI
1. In this randomized controlled trial, the minimum stent area following percutaneous coronary...
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Zinc supplementation may improve metabolic outcomes in patients with non-alcoholic fatty liver disease
1. Patients randomized to have Zinc (Zn) supplementation incorporated into an 8-week diet and...
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ADHD symptoms may be associated with an increased risk of cardiometabolic disorders
1. In this prospective study, ADHD symptoms were associated with an increased risk of...
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High-Dose Docosahexaenoic Acid Does Not Improve Behavioral Functioning in Preterm Infants at 5 Years of Age
1. Docosahexaenoic acid supplementation at the in utero dose for infants born at less than 29...
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Once-weekly insulin icodec non-inferior to daily insulin degludec in patients with type 1 diabetes
1. Mean HbA1c reduction at 26 weeks was comparable in the weekly icodec and daily degludec groups....
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Colchicine does not reduce risk of atrial fibrillation or myocardial injury after non-cardiac surgery
1. Colchicine did not significantly reduce the risk of atrial fibrillation or myocardial injury...
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Erdafitinib or Chemotherapy in Advanced Pre-Treated Urothelial Carcinoma
1. The median overall survival was 12.1 months in the erdafitinib group and 7.8 months in the...
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Pembrolizumab and carboplatin plus docetaxel treatment regimens may provide options for patients with triple-negative breast cancer who are ineligible for anthracycline-based regimens
1. Overall pathologic complete response to treatment of triple-negative breast cancer with a...
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Remote patient monitoring may improve cardiovascular outcomes in patients with hypertension
1. In this observational study, patients in high remote patient monitoring (RPM) practices had...
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Pulsed-field noninferior to thermal ablation in treating paroxysmal atrial fibrillation
1. In this randomized noninferiority trial, pulsed-field ablation was noninferior to thermal...
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Treatment of lower urinary tract symptoms in men in primary care using a conservative intervention
1. This randomised control trial demonstrated that a standardised and manualised intervention in...
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Combined aerobic and strength training most effective for improving diabetes outcomes
1. This randomized pilot study demonstrates that fasting blood glucose (FBG), systolic blood...
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