Optimizing Subtyping-Based Therapy in Triple-Negative Breast Cancer
1. The median progression-free survival was improved with the pooled subtyping-based therapy group...
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chronic-disease
Probiotic supplementation may improve outcomes in patients with type 2 diabetes
1. Patients with type 2 diabetes randomized to using probiotic supplements were found to have...
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Radical cure with primaquine reduces risk of Plasmodium vivax parasitaemia in patients with Plasmodium falciparum infection
1. Patients in the primaquine group reported a significant reduction in parasitemia risk at day 63...
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Mobile application communication may improve palliative care needs met in critically ill patients
1. Families randomized to having access to a mobile application that allowed them to communicate...
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Computed Tomography coronary calcium scores may predict risk of cardiovascular events in cancer patients
1. Despite lower prevalence of traditional cardiovascular risk factors, cancer patients were...
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Pembrolizumab enhances progression-free survival in patients with HER2-positive gastro-esophageal cancer
1. Progression-free survival was significantly greater among patients in the pembrolizumab group...
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Freezing of gait is associated with sleep disorders in patients with Parkinson’s disease
1. In this systematic review, Parkinson’s disease patients with freezing of gait (FOG) experienced...
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Comparison of two chemotherapy regimens in muscle invasive bladder cancer
1. In the perioperative setting, there was no difference between dd-MVAC vs. GC on overall 5-year...
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Systemic Therapy and Stereotactic Body Radiotherapy in Oligoprogressive Breast Cancer or Lung Cancer
1. Progression-free survival in NSCLC was found to be significant with HR 0.41 compared to breast...
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Perioperative pembrolizumab with chemotherapy for gastric and gastroesophageal junction adenocarcinoma improves pathological complete response rate compared with placebo
1. The median overall survival and event-free survival were not statistically different in the...
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Testosterone replacement therapy not associated with prostate cancer risk
1. In a population of men with hypogonadism and PSA concentrations less than 3 ng/mL, patients...
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Semaglutide improves cardiovascular outcomes in obese patients without diabetes
1. In this randomized-controlled trial, the glucagon-like peptide-1 (GLP-1) receptor agonist...
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Percutaneous coronary intervention associated with decreased stable angina symptoms
1. In this randomized controlled trial, percutaneous coronary intervention (PCI) resulted in...
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Discontinuing oxytocin during active labour has no significant impact on neonatal morbidity
1. Neonatal morbidity rate was comparable between the continuous oxytocin and discontinuous...
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Baricitinib protects β-cell function in new-onset type 1 diabetes
1. In this randomized controlled trial, the Janus kinase (JAK) inhibitor baricitinib was...
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Teplizumab effective in maintaining β-cell function in type 1 diabetes
1. In this randomized-controlled trial, two 12-day courses of teplizumab improved C-peptide levels...
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Profiling levels of cognitive functioning at 6 months following traumatic brain injury
1. Many participants who sustained a traumatic brain injury experienced no cognitive dysfunction,...
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Certain genetic predispositions may increase risk of atrial fibrillation among those with high alcohol consumption
1. Among those with high levels of alcohol consumption, a genetic predisposition to poor alcohol...
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Developmental or intellectual disabilities may be associated with increased risk of long COVID
1. Individuals with an intellectual or developmental disability were more likely to experience...
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Rituximab maintenance therapy following autologous stem cell transplant increased survival in young patients with mantle-cell lymphoma
1. In patients with mantle-cell lymphoma who responded to induction therapy and autologous stem...
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