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Cardiology General

UNet retinal blood vessel segmentation algorithm based on improved pyramid pooling method and attention mechanism.

Aug 12, 2021

The segmentation results of retinal vessels have a significant impact on the automatic diagnosis of retinal diabetes, hypertension, cardiovascular and cerebrovascular diseases and other ophthalmic dis...

Diabetes and cardiovascular diseases are associated with the worsening of intermittent hypoxaemia.

Aug 12, 2021

Intermittent hypoxaemia is a risk factor for numerous diseases. However, the reverse pathway remains unclear. Therefore, we investigated whether pre-existing hypertension, diabetes or cardiovascular d...

A Rare Case Report of ST-Segment Elevation Myocardial Infarction and Recurrent Chest Pain in Polyarteritis Nodosa.

Aug 12, 2021

Polyarteritis nodosa (PAN) is a type of vasculitis that mainly affects small and medium-sized blood vessels. The clinical presentation can be nonspecific as weight loss, abdominal pain, and hypertensi...

PPARγ as an indicator of vascular function in an experimental model of metabolic syndrome in rabbits.

Aug 12, 2021

Underlying mechanisms associated with vascular dysfunction in metabolic syndrome (MetS) remain unclear and can even vary from one vascular bed to another.In this study, MetS was induced by a high-fat,...

Association between chronic kidney disease and new-onset dyslipidemia: The Japan Specific Health Checkups (J-SHC) study.

Aug 12, 2021

Dyslipidemias are common among patients with chronic kidney disease (CKD) and are a major risk factor for cardiovascular disease. This study aimed to investigate the association between early-stage CK...

Plasma osteopontin levels and adverse clinical outcomes after ischemic stroke.

Aug 12, 2021

Osteopontin is implicated in atherosclerosis, and its expression is upregulated in response to brain injury. The aim of this study was to prospectively investigate the associations between plasma oste...

Rationale and design of the IRON-AF study: a double-blind, randomised, placebo-controlled study to assess the effect of intravenous ferric carboxymaltose in patients with atrial fibrillation and iron deficiency.

Aug 12, 2021

Atrial fibrillation (AF) is associated with significantly impaired quality-of-life. Iron deficiency (ID) is prevalent in patients with AF. Correction of ID in other patient populations with intravenou...

Soluble C-Type Lectin-Like Receptor 2 Elevation in Patients with Acute Cerebral Infarction.

Aug 09, 2021

Acute cerebral infarction (ACI) includes cardiogenic ACI treated with anticoagulants and atherosclerotic ACI treated with antiplatelet agents. The differential diagnosis between cardiogenic and athero...

[The Clinical Characteristics and Influencing Factors of Patients with Severe COVID-19].

Aug 09, 2021

To investigate the clinical characteristic of coagulation, possible causes and countermeasures of patients with severe corona virus disease 2019 (COVID-19).The clinical data of the 142 patients diagno...

Early switch to oral anticoagulation in patients with acute intermediate-risk pulmonary embolism (PEITHO-2): a multinational, multicentre, single-arm, phase 4 trial.

Aug 09, 2021

Current guidelines recommend a risk-adjusted treatment strategy for the management of acute pulmonary embolism. This is a particular patient category for whom optimal treatment (anticoagulant treatmen...

Daytime sleepiness and risk of stroke: A Mendelian randomization analysis.

Aug 09, 2021

Daytime sleepiness is known to be related to stroke, but whether daytime sleepiness is a risk factor for stroke remains unclear. We conducted a two-sample Mendelian randomization study to assess the r...

Bilingual Abstract Semantic Associative Network Training (BAbSANT): A Polish-English case study.

Aug 09, 2021

This article presents a novel approach to anomia therapy (i.e., BAbSANT: Bilingual Abstract Semantic Associative Network Training) for bilingual persons with aphasia (B-PWA) that capitalizes both on l...

Revascularization versus medical therapy in patients aged 80 and older with stable ischemic heart disease.

Aug 09, 2021

Older patients are underrepresented in landmark randomized trials for stable ischemic heart disease (SIHD). Therefore, we sought to evaluate the benefits of revascularization in patients ≥80 years...

In low-risk patients aged >70-75 with severe aortic stenosis, is transcatheter superior to surgical aortic valve replacement in terms of reported cardiovascular composite outcomes and survival?

Aug 09, 2021

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was: In low-risk patients aged >70-75 with severe aortic stenosis, is transcatheter s...

Clinical outcomes for intracoronary imaging strategies at different medical facilities in Japanese patients with coronary artery disease: the SAKURA imaging PCI Registry.

Aug 09, 2021

The relationships between intracoronary imaging modalities and outcomes among Japanese patients with coronary artery disease (CAD) based on the type of medical facility providing outpatient care remai...

Co-amorphization of atorvastatin by lisinopril as a co-former for solubility improvement.

Aug 09, 2021

The co-amorphous (CAM) technology has attracted extensive attention in recent years because it can improve the solubility and provide a formulation strategy for fixed dose combination for poorly water...

Serum selenium predicts achievement of full-dose cisplatin in concurrent chemoradiotherapy for locally advanced head and neck squamous cell carcinoma: A prospective, observational study.

Aug 09, 2021

Concurrent chemoradiotherapy (CCRT) with three-weekly high-dose cisplatin (100 mg/m) is a standard treatment for locally advanced head and neck squamous cell carcinoma (HNSCC), but compliance with ci...

Introduction of digital therapeutics.

Aug 09, 2021

Digital therapeutics are an emerging type of medical therapy and are defined as evidence-based therapeutic interventions for patients by means of qualified software programs to prevent, manage, or tre...

Association of the odd-chain fatty acid content in lipid groups with type 2 diabetes risk: A targeted analysis of lipidomics data in the EPIC-Potsdam cohort.

Aug 09, 2021

Plasma odd-chain saturated fatty acids (OCFA) are inversely associated with type 2 diabetes (T2D) risk and may serve as biomarkers for dairy fat intake. Their distribution across different lipid class...

Based on urine metabolomics to study the mechanism of Qi-deficiency affecting type 2 diabetes rats using ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.

Aug 09, 2021

Qi-deficiency also called energy deficiency, which approximates to the term of sub-health in contemporary medical theory. Diabetes is similar to the symptoms of "xiaoke" in traditional Chinese medicin...