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Cardiology General

Fibroblast-Specific Proteotranscriptomes

Aug 27, 2021

This study wekk Up to 50% of the adult human sinoatrial node (SAN) is composed of dense connective tissue. Cardiac diseases including heart failure (HF) may increase fibrosis within the SAN pacemaker ...

Late Outcomes Of The RAPID-TnT

Aug 27, 2021

This study well defines how High-sensitivity troponin assays are increasingly being adopted to expedite evaluation of patients with suspected acute coronary syndromes. Few direct comparisons have exam...

Targeting E3 Ubiquitin-Ligase

Aug 26, 2021

The main aim of this study is to understand Without adequate treatment, pathological cardiac hypertrophy induced by sustained pressure overload eventually leads to HF (HF). WW domain- containing E3 ub...

Prioritizing the Role of Major Lipoproteins and Subfractions

Aug 26, 2021

This study states that the Lipoprotein-related traits have been consistently identified as risk factors for atherosclerotic cardiovascular disease, largely on the basis of studies of coronary artery d...

Metabolic Syndrome Mediates

Aug 26, 2021

This study states that Many patients with heart failure with preserved ejection fraction (HFpEF) have metabolic syndrome and develop exercise-induced pulmonary hypertension (EIPH). Increases in pulmon...

Effect of introducing biologics to patients with rheumatoid arthritis on the risk of venous thromboembolism: a nationwide cohort study.

Aug 26, 2021

In the United States, 100,000-300,000 patients die from venous thromboembolism (VTE) each year, with more than 500,000 people related hospitalizations. While in Europe, 500,000 people die from VTE eac...

SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.

Aug 26, 2021

SARS-CoV-2 has been associated with an increased rate of venous thromboembolism in critically ill patients. Since surgical patients are already at higher risk of venous thromboembolism than general po...

Subclinical cardiovascular disease and risk of incident frailty: The British Regional Heart Study.

Aug 26, 2021

Subclinical cardiovascular disease (CVD) is cross-sectionally associated with frailty, but the relationship between subclinical CVD and incident frailty has not been reported. We aimed to assess this ...

Loss of m6A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury.

Aug 26, 2021

N6-Methyladenosine (m6A) is the most commonly chemical modification of messenger RNAs (mRNAs) in eukaryotes, and has been involved in various diseases. However, the role of m6A modification in heart r...

Deceleration capacity is associated with acute respiratory distress syndrome in COVID-19.

Aug 26, 2021

Acute respiratory distress syndrome (ARDS) is considered the main cause of COVID-19 associated morbidity and mortality. Early and reliable risk stratification is of crucial clinical importance in orde...

Associations of telomere length at birth with predicted atherosclerotic lesions and cardiovascular disease risk factors in midlife: A 40-year longitudinal study.

Aug 26, 2021

Adult telomere length (TL) is substantially determined by birth TL, but associations of birth TL with cardiovascular disease (CVD) are unknown.We included 144 adult offspring born in 1959-1966 from th...

Genetic predisposition to COVID-19 may increase the risk of hypertension disorders in pregnancy: A two-sample Mendelian randomization study.

Aug 26, 2021

The aim of this study was to apply the Mendelian randomization (MR) design to explore the potential causal association between COVID-19 and the risk of hypertension disorders in pregnancy.Our primary ...

Dysregulation of Circulating miR-24-3p in Children with Obesity and Its Predictive Value for Metabolic Syndrome.

Aug 26, 2021

Obesity is a major risk factor for metabolic disorders in children. Therefore, it is particularly important to study the abnormal regulation of circulating miR-24-3p in obese children and its predicti...

KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression.

Aug 26, 2021

Krüppel-like factors (KLFs) play essential roles in multiple biological functions, including maintaining vascular homeostasis. KLF11, a causative gene for maturity-onset diabetes of the young type 7,...

Changing the model of care during the COVID-19 pandemic: Same-day discharge of patients undergoing elective invasive cardiac procedures in Hong Kong.

Aug 26, 2021

Despite an evidence-based protocol to facilitate same-day discharge (SDD) of patients undergoing elective intracoronary procedures, overnight hospitalization remains a routine practice.This study aime...

Heart Disease and the Kidneys.

Aug 26, 2021

Clinical Background: The heart can cause kidney disease, and the kidney can cause heart disease. As an example of the first situation, we can mention dilated cardiomyopathies, which can lead to renal ...

Stronger Association of Albuminuria with the Risk of Vascular Complications than Estimated Glomerular Filtration Rate in Type 2 Diabetes.

Aug 26, 2021

Albuminuria is a risk factor for macro- and microvascular complications of type 2 diabetes (T2D).With an increasing trend of normoalbuminuria, however, of the 2 predictors - estimated glomerular filtr...

Dysregulated Phenylalanine Catabolism

Aug 25, 2021

The aim of this study is to understand Aging myocardium undergoes progressive cardiac hypertrophy and interstitial fibrosis with diastolic and systolic dysfunction. Recent metabolomics studies shed li...

Pravastatin versus Placebo

Aug 25, 2021

This study states that Effective screening for term preeclampsia is provided by a combination of maternal factors with measurements of mean arterial pressure, serum placental growth factor and serum s...

Functional Calsequestrin-1

Aug 25, 2021

This study explains that the Calsequestrins (Casqs), comprising the Casq1 and Casq2 isoforms, buffer Ca2+ and regulate its release in the sarcoplasmic reticulum (SR) of skeletal and cardiac muscle, re...