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Cardiology General

Medically Ill hospitalized Patients for COVID-19 THrombosis Extended ProphyLaxis with rivaroxaban ThErapy: Rationale and Design of the MICHELLE Trial.

Sep 06, 2021

The devastating Coronavirus disease (COVID-19) pandemic is associated with a high prothrombotic state. It is unclear if the coagulation abnormalities occur because of the direct effect of SARS-CoV-2 o...

The additive value of copeptin for early diagnosis and prognosis of acute coronary syndromes.

Sep 06, 2021

One promising biomarker that has received substantial interest for the evaluation of suspected acute coronary syndromes (ACS) is copeptin. Therefore, our goal was to assess the additive value of copep...

Mineralocorticoid receptors in pulmonary hypertension and right heart failure: From molecular biology to therapeutic targeting.

Sep 06, 2021

Pulmonary hypertension (PH) is a devastating condition characterized by pulmonary vascular remodelling, leading to progressive increase in pulmonary artery pressure and subsequent right ventricular fa...

Propranolol and metoprolol: Two comparable drugs with very different post-mortem toxicological profiles.

Sep 06, 2021

Propranolol is a widely used beta-blocker mainly prescribed for the treatment of hypertension and other cardiac conditions. This medicine is also a frequent finding in drug screens, but little is know...

Estradiol ameliorates metformin-inhibited Sertoli cell proliferation via AMPK/TSC2/mTOR signaling pathway.

Sep 06, 2021

Metformin is a commonly used for treating type 2 diabetes and it acts on a variety of organs including the male reproductive system. 17β-estradiol plays an important role in Sertoli cell (SC) prolife...

Chlordane exposure causes developmental delay and metabolic disorders in Drosophila melanogaster.

Sep 06, 2021

The incidence of metabolic diseases is increasing every year, and several studies have highlighted the activity of persistent organic pollutants (POPs) in causing hyperlipidemia and diabetes, and thes...

The Effect of Bone Marrow Mesenchymal Stem Cell Sheets on Skin Capillary Parameters in a diabetic wound model: A Novel Preliminary Study

Sep 06, 2021

Treatment with BMMSCs has anti-inflammatory, tissue regenerative, angiogenic, and immune-stimulating effects. When using as sheets or accumulate, BMMSCs causes the development of neoangiogenesis in da...

ALDH2, ADCY3 and BCMO1 polymorphisms and lifestyle-induced traits are jointly associated with CAD risk in Chinese Han people.

Sep 06, 2021

To investigate associations of genetic factors and environmental factors with coronary artery disease (CAD), we collected medical reports, lifestyle details, and blood samples of 2113 individuals, and...

Implications of the 2019 American College of Cardiology/American Heart Association Primary Prevention Guidelines and potential value of the coronary artery calcium score among South Asians in the US: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) study.

Sep 06, 2021

South Asian (SA) ethnicity is associated with an increased risk of atherosclerotic cardiovascular disease (ASCVD). However, the implications of considering SA ethnicity as a "risk-enhancing factor" pe...

AFCNNet: Automated detection of AF using chirplet transform and deep convolutional bidirectional long short term memory network with ECG signals.

Sep 06, 2021

Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and is characterized by the heart's beating in an uncoordinated manner. In clinical studies, patients often do not have visible s...

Direct Oral Anticoagulants Versus Warfarin for Treatment of Thrombosis or Atrial Fibrillation in Patients With Cirrhosis: A Retrospective Cohort Study.

Sep 06, 2021

Evidence for direct oral anticoagulants (DOACs) in patients with cirrhosis is limited. Few patients with Child-Turcotte-Pugh (CTP) class B and C cirrhosis have been studied.To compare major bleeding r...

Assessment of patients with a suspected cardioembolic ischemic stroke. A national consensus statement.

Sep 06, 2021

Several cardiovascular, structural, and functional abnormalities have been considered as potential causes of cardioembolic ischemic strokes. Beyond atrial fibrillation, other sources of embolism clear...

Examination of anticoagulation prescription among elderly patients with atrial fibrillation after in-hospital fall.

Sep 06, 2021

Mechanical fall is common among elders and has been associated with a lack of anticoagulant therapy among patients with atrial fibrillation (AF). However, anticoagulant therapy is recommended despite ...

Mental Health Neglect Among Physicians

Sep 05, 2021

Previous research has suggested high rates of suicide and depression among physicians when compared with the general public. Debilitating mental illness can critically impact physicians’ ability to ...

Cooperative Binding Of ETS2 And NFAT Links

Aug 30, 2021

This study states that Cardiac hypertrophy is an independent risk factor for heart failure, a leading cause of morbidity and mortality globally. The calcineurin/NFAT (nuclear factor of activated T cel...

Incidence of and risk factors for new-onset deep venous thrombosis after intertrochanteric fracture surgery.

Aug 30, 2021

This study aimed to investigate the incidence of and risk factors for postoperative new-onset deep venous thrombosis (PNO-DVT) following intertrochanteric fracture surgery. Information on 1672 patient...

Safety and effectiveness of dabigatran in routine clinical practice: the RE-COVERY DVT/PE study.

Aug 30, 2021

RE-COVERY DVT/PE is a two-phase, international, observational study of anticoagulant therapy in patients with deep vein thrombosis and/or pulmonary embolism (DVT/PE). The objective of the second phase...

Pulmonary embolism and deep vein thrombosis: Similar but different.

Aug 30, 2021

Pulmonary embolism (PE) and deep vein thrombosis (DVT), the two clinical manifestations of venous thromboembolism (VTE), constitute a major global burden of cardiovascular disease. They are often refe...

Analysis of the application of "psycho-cardiology" model in nursing care of acute stroke patients with depression.

Aug 30, 2021

To evaluate the effect of "psycho-cardiology" model in nursing care of acute stroke patients with depression.Seventy-eight acute stroke patients with depression were selected for this prospective stud...

Real-World Experience With the SAPIEN 3 Ultra Transcatheter Heart Valve: A Propensity-Matched Analysis From the United States.

Aug 30, 2021

Paravalvular regurgitation (PVR) after transcatheter aortic valve replacement is associated with adverse clinical outcomes. The SAPIEN 3 Ultra (Ultra) is a new generation balloon-expandable transcathe...