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Cardiology General

Macroscopic characteristics of the native liver in children with MPV17-related mitochondrial DNA depletion syndrome: an indication for performing liver transplantation?

Sep 20, 2021

Mitochondrial respiratory chain disorders (MRCDs) are rare conditions with various clinical manifestations that depend on the genetic type, with subsequent severity of the liver disease. Clinical pres...

NLRP3 inflammasome and IL-1β pathway in type 2 diabetes and atherosclerosis: friend or foe?

Sep 20, 2021

Type 2 diabetes and atherosclerosis have gradually garnered great attention as inflammatory diseases. Previously, the fact that Interleukin-1β (IL-1β) accelerates the development of type 2 diabetes ...

Liposome interaction with macrophages and foam cells for atherosclerosis treatment: effects of size, surface charge and lipid composition.

Sep 20, 2021

Liposomes are potential drug carriers for atherosclerosis therapy due to low immunogenicity and ease of surface modifications that allow them to have prolonged circulation half-life and specifically t...

Time in therapeutic range values of patients using warfarin and factors that influence time in therapeutic range.

Sep 20, 2021

The time in therapeutic range (TTR) of international normalized ratio (INR) is essential for the safety and efficacy of warfarin treatment. In this study, we aimed to determine TTR and the factors tha...

Key Role of Personalized Dosimetry in Dose Adjustment for Selective Internal Radiotherapy: Retrospective Study of Patients Treated With 90Y Resin Microspheres.

Sep 13, 2021

Selective internal radiotherapy with 90Y microspheres is widely used for the treatment of patients with liver cancer. A dosimetric analysis using the dosimetry software Simplicit90y (Boston Scientific...

Medium-term Outcomes Following Inferior Vena Cava Reconstruction for Acute and Chronic Deep Vein Thrombosis and Retroperitoneal Fibrosis.

Sep 13, 2021

This study aimed to evaluate technical and clinical outcomes following endovascular inferior vena cava reconstruction in patients with non-malignant obstruction.Pre-operative, procedural and follow-up...

Meta-Analysis and Systematic Review of Randomized Controlled Trials Assessing the Role of Thromboprophylaxis post-Vascular Surgery.

Sep 13, 2021

Venous thromboembolism (VTE) is a well-known complication associated with surgical procedures. The implementation of thromboprophylaxis in this population has become a vital aspect of peri-operative c...

Bleeding risk in patients with cardiac disease from ischaemic stroke reperfusion therapy: an update.

Sep 13, 2021

Intravenous tissue plasminogen activator (rtPA) and arterial endovascular therapy (ET) rapidly restore cerebral perfusion in eligible patients who had an acute ischaemic stroke (AIS). It is unknown wh...

A Review of the Clinical Pharmacology of Pelacarsen: A Lipoprotein(a)-Lowering Agent.

Sep 13, 2021

Patients with genetically associated elevated lipoprotein(a) [Lp(a)] levels are at greater risk for coronary artery disease, heart attack, stroke, and peripheral arterial disease. To date, there are n...

Prevalence and risk factors of labor-onset hypertension: A multicenter study in Japan.

Sep 13, 2021

To investigate the prevalence and risk factors of labor-onset hypertension (LOH), defined as hypertension first detected during labor among women without hypertension prior to admission for labor.In t...

A Predictive Model for Functional Outcome in Patients with Acute Ischemic Stroke Undergoing Endovascular Thrombectomy.

Sep 13, 2021

Endovascular thrombectomy (EVT) is a well-established treatment of acute ischemic stroke. Variability in outcomes among thrombectomy patients results in a need for patient centered approaches to recov...

Inhibition of p38 MAP Kinase in Patients with ST-Elevation Myocardial Infarction - Findings from the LATITUDE TIMI 60 Trial.

Sep 13, 2021

p38 mitogen activated kinase (MAPK) mediates the response to pro-inflammatory cytokines following myocardial infarction (MI) and is inhibited by losmapimod.LATITUDE-TIMI 60 (ClinicalTrials.gov NCT0214...

Statin use for primary prevention in patients with type 2 diabetes: Can it benefit all ages? - A nationwide propensity-matched cohort study.

Sep 13, 2021

This study aims to investigate whether statin use is associated with a reduction in CVD and mortality in patients with type 2 diabetes without CVD.A propensity score-matched cohort analysis using retr...

Incremental Value of Global Longitudinal Strain in the Long-term Prediction of Heart Failure Among Patients with Coronary Artery Disease.

Sep 13, 2021

Heart failure (HF) remains a common complication for patients with coronary artery disease (CAD), especially after acute myocardial infarction. Although left ventricular ejection fraction (LVEF) is co...

Relation of the Metabolic Syndrome to Incident Colorectal Cancer in Young Adults Aged 20 to 49 Years.

Sep 13, 2021

Onco-cardiology is the emerging field, and the concept of shared risk factor holds an important position in this field. The increasing prevalence of colorectal cancer (CRC) in young adults is a critic...

Differential influences of dietary sodium on blood pressure regulation based on race and sex.

Sep 13, 2021

There are clear differences between men and women, and differences among races, in the incidence and prevalence of hypertension. Furthermore, there is extensive inter-individual variability among huma...

Vasodilator use in precapillary pulmonary hypertension with end stage kidney disease: A single center experience.

Sep 13, 2021

Pulmonary hypertension is commonly seen in end stage kidney disease and is most commonly due to elevated left heart pressures. There is limited data about vasodilator use during the management of Grou...

Hydrogen sulfide alleviates salinity stress in Cyclocarya paliurus by maintaining chlorophyll fluorescence and regulating nitric oxide level and antioxidant capacity.

Sep 13, 2021

Cyclocarya paliurus is commonly used to treat diabetes in China. However, the natural habitats of C. paliurus are typically affected by salt stress. Hydrogen sulfide (HS) is a growth regulator that is...

Analytical approaches to assess metabolic changes in psoriasis.

Sep 13, 2021

Psoriasis is one of the most common human skin diseases, although its development is not limited to one tissue, but is associated with autoimmune reactions throughout the body. Overproduction of pro-i...

Management of Neurogenic Orthostatic Hypotension in Neurodegenerative Disorders: A Collaboration Between Cardiology and Neurology.

Sep 13, 2021

Treatment of patients with α-synucleinopathies (e.g., Parkinson disease, multiple system atrophy, diffuse Lewy body disease) may require clinicians to manage both neurologic and cardiovascular issues...