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Cardiology General

Innate Immune Nod1/RIP2

Oct 01, 2021

This study states that Cardiac hypertrophy is a key biological response to injurious stresses such as pressure overload and, when excessive, can lead to heart failure. Innate immune activation by dang...

Rivaroxaban and Aspirin in Peripheral Artery

Oct 01, 2021

This study states that The VOYAGER PAD trial (Vascular Outcomes Study of ASA Along With Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery Disease) demonstrated super...

VERTIS-CV

Oct 01, 2021

In this issue of Circulation, Cosentino and colleagues1 report the results of prespecified analyses from the VERTIS-CV trial (Evaluation of Ertugliflozin Efficacy and Safety Cardiovascular Outcomes Tr...

Efficacy of Ertugliflozin

Oct 01, 2021

This study states that Patients with type 2 diabetes mellitus (T2DM) are at high risk for heart failure (HF).1–4 The lifetime adjusted cumulative hazard for incident HF in patients with T2DM, hypert...

Prevention of Complications

Oct 01, 2021

This study states that Critically ill patients are inherently susceptible to a multitude of complications related to both the severity of underlying illness and the need for intensive care therapies.1...

An Overview on Antithrombotic Therapy

Oct 01, 2021

Patients with diabetes mellitus (DM) are characterized by enhanced thrombotic risk attributed to multiple mechanisms including hyperreactive platelets, hypercoagulable status, and endothelial dysfunct...

Dual Functional States

Oct 01, 2021

Mutations in the human desmin gene cause myopathies and cardiomyopathies. This study aimed to elucidate molecular mechanisms initiated by the heterozygous R406W-desmin mutation in the development of a...

Signalosome-Regulated Serum

Oct 01, 2021

This study states that Concentric and eccentric cardiac hypertrophy are associated with pressure and volume overload, respectively, in cardiovascular disease both conferring an increased risk of heart...

Growth Differentiation Factor

Oct 01, 2021

This study states Growth differentiation factor 15 (GDF-15) is a strong prognostic marker in sepsis and cardiovascular disease (CVD). The prognostic value of GDF-15 in coronavirus disease 2019 (COVID-...

Comprehensive Metabolic Phenotyping

Sep 30, 2021

This study states that Whereas cardiovascular disease (CVD) metrics define risk in individuals >40 years of age, the earliest lesions of CVD appear well before this age. Despite the role of metabol...

The Use of Patient Reported Outcome Measures (PROMs) 6 Months Post-Stroke and Their Association with the National Institute of Health Stroke Scale (NIHSS) on Admission to Hospital.

Sep 27, 2021

Patient Reported Outcome Measures (PROMs) assess clinical outcomes from the perspective of the patient. The stroke community recommended fifteen questions for use in stroke survivors, based on the est...

Effects of Cognitive Sensory Motor Training on Lower Extremity Muscle Strength and Balance in Post Stroke Patients: A Randomized Controlled Study.

Sep 27, 2021

Sensory motor impairment, the most common neuromuscular condition in stroke patients, often contributes to muscle weakness and imbalance.The purpose of this research was to investigate the effects of ...

Survey on sodium and potassium intake in patients with hypertension in China.

Sep 27, 2021

Sodium and potassium intake in hypertensive patients in China is not clear. The authors aimed to investigate the distribution of sodium and potassium intake in hypertensive patients in China, and to a...

Evaluating a standardized protocol for the management of diabetes insipidus in pediatric neurosurgical patients.

Sep 27, 2021

Central diabetes insipidus (DI) is a known complication following surgical resection of a suprasellar mass. There are limited data analyzing the outcomes of a standardized protocol for the management ...

Rapid Detection of Gut Microbial Metabolite Trimethylamine N-Oxide for Chronic Kidney Disease Prevention.

Sep 27, 2021

The gut microbiota plays a critical role in chronic kidney disease (CKD) and hypertension. Trimethylamine-N-oxide (TMAO) and trimethylamine (TMA) are gut microbiota-derived metabolites, and both are k...

Retrospective cohort study of new-onset atrial fibrillation in acute pulmonary embolism on prognosis.

Sep 27, 2021

To investigate the characteristics of new-onset atrial fibrillation (AF) and its impact on prognosis in acute pulmonary embolism (aPE).A retrospective cohort study SETTING: The study cohort included p...

Spontaneous Coronary Artery Dissection with Sudden Cardiac Arrest in a Female Patient During Her Postpartum Period: A Case Report and Review.

Sep 20, 2021

BACKGROUND Spontaneous coronary artery dissection (SCAD) is a rare cause of acute myocardial infarction, and the literature is undecided on the etiology, predisposing factors, and susceptible populati...

Transcatheter Aortic Valve Replacement With Self-Expandable Supra-Annular Valves for Degenerated Surgical Bioprostheses: Insights From Transcatheter Valve Therapy Registry.

Sep 20, 2021

Background Transcatheter aortic valve replacement with supra-annular transcatheter heart valves has been adopted in patients with degenerated surgical aortic valves. The next generation self-expanding...

An Echocardiography-derived Calcium Score as a Predictor of Major Adverse Cardiovascular Events in Peritoneal Dialysis Patients - A Prospective Cohort Study.

Sep 20, 2021

An echocardiography-derived calcium score (ECS) has been shown to predict CV mortality in the general population but has not been utilized in the dialysis population.We conducted a prospective cohort ...

Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species.

Sep 20, 2021

Myocardial ischemia-reperfusion (MIR) injury is a major cause of adverse outcomes of revascularization after myocardial infarction. To identify the fundamental regulator of reperfusion injury, we perf...