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Cardiology General

Systematic exploration of the potential material basis and molecular mechanism of the Mongolian medicine Nutmeg-5 in improving cardiac remodeling after myocardial infarction.

Nov 22, 2021

Nutmeg-5, which consists of Myristica fragrans Houtt., Aucklandia lappa Decne., Inula helenium L., Fructus Choerospondiatis and Piper longum L., is an ancient and classic formula in traditional Mongol...

Irisin lowers blood pressure in Zucker diabetic rats by regulating the functions of renal angiotensin II type 1 receptor via the inhibition of the NF-κB signaling pathway.

Nov 22, 2021

Irisin, a novel myokine, has been identified to exert a series of favorable effects on metabolic diseases, including diabetes and obesity. This study aimed to explore the effects of chronic irisin adm...

Effect of the consumption of hesperidin in orange juice on the transcriptomic profile of subjects with elevated blood pressure and stage 1 hypertension: A randomized controlled trial (CITRUS study).

Nov 22, 2021

Hesperidin exerts cardiovascular beneficial effects, but its mechanisms of action remain undefined. In a previous study we demonstrated that a single dose and a 12-week treatment of hesperidin decreas...

Is the Risk Really Shared? A Retrospective Analysis of Healthcare Costs of Patients With Type 2 Diabetes Mellitus on a Capitation Model.

Nov 22, 2021

Private managed healthcare organizations in South Africa (SA) use a capitation model of care for patients within their healthcare delivery systems for the optimal management of type 2 diabetes mellitu...

Virtual screening of dipeptidyl peptidase-4 inhibitors using quantitative structure-activity relationship-based artificial intelligence and molecular docking of hit compounds.

Nov 22, 2021

Dipeptidyl peptidase-4 (DPP-4) inhibitors are becoming an essential drug in the treatment of type 2 diabetes mellitus; however, some classes of these drugs exert side effects, including joint pain and...

Model-based adaptive filter for a dedicated cardiovascular CT scanner: Assessment of image noise, sharpness and quality.

Nov 22, 2021

Filtered back projection (FBP) and adaptive statistical iterative reconstruction (ASIR) are ubiquitously applied in the reconstruction of coronary CT angiography (CCTA) datasets. However, currently no...

CHA DS -VASc impact on risk following percutaneous coronary intervention in atrial fibrillation.

Nov 22, 2021

In 2010, the European Society of Cardiology Guidelines on atrial fibrillation (AF) introduced the CHA DS -VASc score to guide initiation of oral anticoagulation. In patients with AF undergoing percuta...

Age-related changes in clinical characteristics and outcomes of chronic heart failure outpatients in a cardiology setting. A report from the Italian Network on Heart Failure.

Nov 22, 2021

Ageing and comorbidities are increasing frailty/complexity of heart failure (HF) patients globally. We assessed evolving trends over two decades according to patients' age and time of recruitment in a...

Post-Operative Red Cell Distribution Width Increase May Predict Mortality in Patients Operated for Hip Fracture.

Nov 15, 2021

Hip fractures, with significant morbidity and mortality, increase day by day with the aging population. Inflammation may play a critical role in addition to deep vein thrombosis due to pulmonary embol...

Yosprala: Coordinated Delivery of a Proton Pump Inhibitor and Aspirin.

Nov 15, 2021

Review the pharmacology, pharmacokinetics, efficacy, and safety of Yosprala (aspirin and omeprazole). A literature search was conducted using PubMed with the terms "Yosprala," "PA8140," and "PA32540...

Treatment with Multiple Therapeutic Classes of Medication is Associated with Survival after Stroke.

Nov 15, 2021

Treatment with several therapeutic classes of medication is recommended for secondary prevention of stroke. We analysed the associations between the number of classes of prevention medications supplie...

[Analysis of incidence and risk factors for postoperative venous thromboembolism in patients with stageⅠ a non-small-cell lung cancer].

Nov 15, 2021

To analyze the incidence and risk factors for postoperative venous thromboembolism(VTE) in patients with stage Ⅰa non-small-cell lung cancer(NSCLC), so as to find evidence for further research of p...

A case report of atraumatic splenic rupture after coronary stenting and dual antiplatelet therapy: Causality or relationship?

Nov 15, 2021

Atraumatic splenic rupture(ASR) is a rare event with challenging management, due to absence of clinical history of trauma and delayed diagnosis. Current clinical report could provide detailed informat...

Workflow Automation for a Virtual Hypertension Management Program.

Nov 15, 2021

Hypertension is a modifiable risk factor for numerous comorbidities and treating hypertension can greatly improve health outcomes. We sought to increase the efficiency of a virtual hypertension manage...

Correlates of Insulin Selection as a First-Line Pharmacological Treatment for Gestational Diabetes.

Nov 15, 2021

 The aim of this study was to investigate prenatal factors associated with insulin prescription as a first-line pharmacotherapy for gestational diabetes mellitus (GDM; compared with oral antidiabeti...

[Analysis of hub genes and molecular mechanisms in non-alcoholic steatohepatitis based on the gene expression omnibus database].

Nov 15, 2021

To explore the hub genes and mechanisms in the pathological process of non-alcoholic steatohepatitis (NASH) by bioinformatics methods. Microarray datasets GSE89632 were downloaded from the Gene Expr...

Usefulness of postoperative high-sensitive troponin T measurement and implications for defining type 5 infarction.

Nov 15, 2021

Guidelines indicate for type 5 myocardial infarction (MI) that postoperative troponin need not be exclusively ischemic but may also be caused by epicardial injury. Complexity arises from the introduct...

Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation.

Nov 15, 2021

Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in t...

Survey of clinical practice pattern in Germany's certified chest pain units : Adherence to the European Society of Cardiology guidelines on non-ST-segment elevation acute coronary syndrome.

Nov 15, 2021

We aimed to analyze the 2020 standard of care in certified German chest pain units (CPU) with a special focus on non-ST-segment elevation acute coronary syndrome (NSTE-ACS) through a voluntary surve...

Incidence, and preoperative and intraoperative prognostic factors of deep venous thrombosis in patients with glioma following craniotomy.

Nov 08, 2021

The aim of this study was to investigate the incidence of deep vein thrombosis (DVT) and the preoperative and intraoperative risk factors associated with DVT in glioma patients METHODS: We conducted a...