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Cardiology General

Prognostic and predictive factors in patients with advanced HCC and elevated alpha-fetoprotein treated with ramucirumab in two randomized Phase III trial.

Mar 07, 2022

Ramucirumab is an effective treatment for patients with advanced HCC (aHCC) and baseline AFP {greater than or equal to}400 ng/mL. We aimed to identify prognostic and predictive factors of response to ...

Development and validation of an LC-MS/MS based quantitative assay for marmoset insulin in serum.

Mar 07, 2022

Insulin is a peptide hormone that is secreted by the β cells of the pancreas and is essential to the metabolism of carbohydrates, fats, and proteins in the body. The marmoset insulin peptide is not h...

The melatonin MT receptor is involved in the anti-apoptotic effects of melatonin in rats with type 2 diabetes mellitus.

Mar 07, 2022

Type 2 diabetes mellitus (T2DM) is a widely prevalent chronic disease and risk factor for several other diseases, such as cardiovascular diseases, neuropathy, nephropathy, and retinopathy. Apoptosis i...

Heart failure and catheter ablation of atrial fibrillation: Navigating the difficult waters of heart failure phenotypes.

Mar 07, 2022

The use of catheter ablation of atrial fibrillation (AFA) is increasing and it has now been extended to include higher risk patients with heart failure (HF), based on evidence from observational studi...

Transvenous electrical cardioversion of atrial fibrillation in horses: Horse and procedural factors correlated with success and recurrence.

Mar 07, 2022

Transvenous electrical cardioversion (TVEC) is 1 of the main treatment options for atrial fibrillation (AF) in horses. Large-scale studies on factors affecting success and prognosis have primarily bee...

Guidance for the Treatment of Juvenile Idiopathic Arthritis: Suggestions for Nonpharmacologic Therapies, Medication Monitoring, Immunizations, and Imaging, published by the American College of Rheumatology in 2021.

Mar 04, 2022

For a study, regardless of the JIA phenotype, researchers sought to give care guidelines for juvenile idiopathic arthritis (JIA), focusing on nonpharmacologic therapy, medication monitoring, vaccinati...

In Elderly Patients With Severe, Symptomatic Degenerative Mitral Regurgitation, Transcatheter Edge-to-Edge Repair Has Been Linked To Enhanced Survival.

Mar 04, 2022

For functional mitral regurgitation, randomized clinical trials showed that transcatheter edge-to-edge repair (TEER) was more effective than medical care in improving outcomes; however, there were few...

The PolyIran-Liver Study Tested a Polypill for Cardiovascular Disease Prevention, Emphasizing Non-Alcoholic Steatohepatitis

Mar 04, 2022

For a study, it was determined that people with non-alcoholic steatohepatitis or high liver enzymes had a higher risk of cardiovascular disease, although they were frequently excluded from preventativ...

Effect of Baseline Renal Dysfunction on Cardiac Outcomes and End-Stage Renal Disease in Heart Failure Patients With Mitral Regurgitation

Mar 04, 2022

In individuals with heart failure (HF) and significant secondary mitral regurgitation (MR), baseline renal dysfunction (RD) had a negative impact on outcomes. Heart failure and MR exacerbate the progn...

In Secondary Prevention, Targeted Proteomics Improves Cardiovascular Risk Prediction

Mar 04, 2022

For a study, it was determined that the risk ratings did not reliably identify patients at the highest risk of recurring atherosclerotic cardiovascular disease (ASCVD) and required more extensive trea...

At the Initiation of Human Ventricular Fibrillation, the Purkinje Network and Myocardial Substrate: Implications for Catheter Ablation

Mar 04, 2022

Human ventricular fibrillation (VF) mapping data was scarce. In patients with structural cardiac abnormalities, researchers did a thorough mapping of the activities that led to VF's start and targeted...

Study on the High-Sensitivity Cardiac Troponin I After Coronary Artery Bypass Grafting for Post-Operative Decision-Making

Mar 04, 2022

The postoperative evaluation of patients following coronary artery bypass graft (CABG) surgery was currently guided by troponin cut-offs derived utilizing non-high-sensitive troponin assays or that we...

Contribution of Cereblon to Cardiac Dysfunction by Degrading Cav1.2α

Mar 04, 2022

Cereblon (CRBN) was an E3 ubiquitin ligase complex substrate receptor that targeted ion channel proteins. L-type voltage-dependent calcium channels (LTCCs) density and dysfunction were essential in he...

Study on the Silent Brain Infarcts Impact on Cognitive Function in Atrial Fibrillation

Mar 04, 2022

The research set out to determine whether clinically apparent and silent brain injuries were linked to cognitive impairment in atrial fibrillation (AF) patients. The 1,227 AF patients in prospective, ...

Study on the Ethnicity-Dependent Performance of the Global Registry of Acute Coronary Events Risks Scores for Forecasting Non-ST-Segment Elevation Myocardial Infarction In-Hospital Mortality.

Mar 04, 2022

The Global Registry of Acute Coronary Events (GRACE) score was created to determine risk in individuals with the acute coronary syndrome who have or lack ST-segment elevation. Little was known regardi...

Study on the QRS Micro-Fragmentation as a Mortality Predictor

Mar 04, 2022

The abnormal appearance of the QRS complex, which was fragmented and has a visible notch on a standard 12-lead electrocardiogram (ECG), was considered to indicate depolarization abnormalities and impl...

Study on the Sodium-Containing Acetaminophen and Cardiovascular Results in Individuals With and Without Hypertension

Mar 04, 2022

Past research linked high salt consumption to an increased risk of cardiovascular disease (CVD) and all-cause mortality in persons with hypertension. The research conclusions on the impact of intake i...

Corneal Striate in the Eyes After Glaucoma Surgery: Risk Factors

Mar 01, 2022

For a study, it was determined that corneal striae were shown to have a steeper cornea, induced astigmatism, and increased corneal hysteresis (CH), which indicated a link between striae, corneal morph...

Ocular Compressions in Digital Form Tube Shunts Lower Intraocular Pressure in the Eyes

Mar 01, 2022

For a study, it was determined that when comparing eyes with tube shunts to eyes without filtering operations, digital ocular compressions (DOCs) reduced intraocular pressure by a significant amount a...

In Primary Angle Closure Disease, Anterior Segment OCT Was Compared To Normal Subjects With Similar Shallow Anterior Chamber

Mar 01, 2022

Diagnosis of patients with the angle-closure disease (PACD) had relatively narrow-angle structures measured by swept-source optical coherence tomography (SS-OCT) at 250 μm from the with scleral spur ...