May 20, 2022

ANGPTL3 genetic loss-of-function mutations are related to reduced plasma lipid levels. Vupanorsen is a hepatically targeted antisense oligonucleotide that suppresses the creation of the protein Angiop...

May 20, 2022

Catheter ablation as a first-line treatment for ventricular tachycardia (VT) at the time of ICD implantation has not been incorporated into clinical recommendations. Furthermore, there was an unmet cl...

May 20, 2022

The DECLARE-TIMI 58 study found that dapagliflozin improved heart failure and renal outcomes in individuals with type 2 diabetes mellitus (T2DM) who had or were at high risk for cardiovascular disease...

May 20, 2022

1. Physical activity was significantly associated with a decreased incidence of all-cause dementia and Alzheimer’s disease, irrespective of follow-up length, baseline age and study quality. 2...

May 20, 2022

Although early detection of structural heart disease improves patient outcomes, many patients remain undiagnosed. While echocardiography is impracticable for population screening, electrocardiogram (E...

May 20, 2022

There was strong evidence to support using a single high-sensitivity cardiac troponin T (hs-cTnT) test with a limit of detection (LoD) of 5 ng/L to rule out acute myocardial infarction. According to t...

May 20, 2022

Inadequate nutritional intake is a major factor in chronic cardiometabolic disorders. In addition, dietary quality differences contribute to socioeconomic and racial, and ethnic health inequities. Foo...

May 20, 2022

Due to bleeding concerns, extended thromboprophylaxis was not commonly used in critically sick medical patients. The MAGELLAN (Multicenter, Randomized, Parallel-Group Efficacy and Safety Study for the...

May 20, 2022

Hyperkalemia raises the risk of cardiac arrhythmias and mortality and restricts the use of renin-angiotensin-aldosterone system inhibitors and mineralocorticoid receptors antagonists, which improve cl...

May 20, 2022

For a TEXTMEDS study (Text Messages to Improve Medication Adherence and Secondary Prevention After Acute Coronary Syndrome), researchers sought to determine the impact of a text message–delivered ca...

May 16, 2022

The management of patients with stroke is often multidisciplinary, involving various specialties and healthcare professionals. Given the common shared risk factors for stroke and cardiovascular diseas...

May 16, 2022

Heart failure with preserved ejection fraction (HFpEF) is a syndrome with a heterogeneous cluster of causes, including non-resolving inflammation, endothelial dysfunction, and multi-organ defects. The...

May 16, 2022

Oropharyngeal dysphagia (OD) affects 40-81% of patients after stroke. A recent systematic review on the costs of OD and its main complications showed higher acute and long-term costs for those patient...

May 16, 2022

To assess readmission rates in nonagenarians (age ≥ 90 years) with ST-elevation myocardial infarction (STEMI) following primary percutaneous coronary intervention (pPCI) versus no pPCI.There a...

May 16, 2022

Previous systematic reviews reported that serum vitamin D deficiency was associated with risk of hypertension. The aim was to conduct a meta-epidemiological analysis for evaluating the potential effec...

May 16, 2022

Inadequate sleep duration is associated with a higher risk of type 2 diabetes and the relationship is nonlinear. We aim to assess the curve relationship between night sleep duration and the incidence ...

May 16, 2022

The effectiveness of continuous glucose monitoring (CGM) in maintaining glycaemic control in type 1 (T1DM) and type 2 diabetes mellitus (T2DM) has been well demonstrated. However, the degree of glycae...

May 16, 2022

Evolutionary medicine studies the role of evolution in health problems. Diseases are considered as phenotypes generated by the expression of sets of genes and a complex interplay with the environment....

May 16, 2022

Coronary distensibility index (CDI), as an early predictor of cardiovascular diseases, has the potential to complement coronary computed tomography angiography (cCTA)-derived fractional flow reserve (...

May 16, 2022

Cancer antigen 125 (CA125) is clinically used to monitor response to therapy in ovarian cancer and has been proposed for use in detecting ovarian cancer. This population-based study examines how demog...