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Cardiology General

The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis.

Mar 12, 2020

Vascular smooth muscle cells (VSMCs) are an important source of foam cells in atherosclerosis. The mechanism for VSMC-derived foam cell formation is, however, poorly understood. Here, we demonstrate t...

Is 64-Row Multi-Detector Computed Tomography Angiography Equal to Digital Subtraction Angiography in Treatment Planning in Critical Limb Ischemia?

Mar 12, 2020

Critical limb ischemia (CLI) represents the end stage of peripheral arterial disease (PAD). It is defined as a chronic ischemic rest pain, ulcers or gangrene, attributable to proven arterial occlusive...

Crucial Gene Identification in Carotid Atherosclerosis Based on Peripheral Blood Mononuclear Cell (PBMC) Data by Weighted (Gene) Correlation Network Analysis (WGCNA).

Mar 12, 2020

BACKGROUND Many patients are not responsive or tolerant to medical therapies for carotid atherosclerosis. Thus, elucidating the molecular mechanism for the pathogenesis and progression of carotid athe...

Evaluation of Subclinical Atherosclerosis in Turkish Patients with Acne Vulgaris Receiving Systemic Isotretinoin.

Mar 12, 2020

Studies conducted on isotretinoin have shown that it may indirectly lead to atherosclerosis. The objective of this study was to determine the effect of systemic isotretinoin on subclinical atheroscler...

Hypertrophic Cardiomyopathy in "Real-World" Community Cardiology Practice.

Mar 12, 2020

Differences in presentation and natural history of hypertrophic cardiomyopathy (HC) between community cardiology practice and referral centers has been a source of considerable uncertainty. We report ...

Aspirin for Primary CVD Prevention

Mar 10, 2020

Data suggest that several million individuals are currently prescribed aspirin as prophylaxis against cardiovascular disease (CVD) events, despite the efficacy and safety of doing so remaining uncle...

Excess Mortality Observed for Older Adults With BP Below 130/80 mm Hg

Mar 10, 2020

TUESDAY, March 10, 2020 (HealthDay News) -- For older adults, blood pressure (BP) <130/80 mm Hg is associated with excess mortality, according to a study published online March 5 in Age and Ageing...

Variations in Incidence of Venous Thromboembolism in Low-, Middle- and High-Income Countries.

Mar 09, 2020

To examine the rates of VTE in high-income, upper middle-income and lower middle/low-income countries (World Bank Classification).We examined the rates of VTE in high-income, upper middle-income and l...

Inferior Vena Cava Filter Broken and Migrated to Left Ventricle with Destruction of Mitral Valve.

Mar 09, 2020

Inferior vena caval(IVC) filters are used for patients with pulmonary embolism or those with risk of embolization. Here we present a case of a 38-year-old man who underwent placement of an IVC filter ...

External validation of the SOX-PTS score in a prospective multicenter trial of patients with proximal deep vein thrombosis.

Mar 09, 2020

Using data from the SOX Trial, we recently developed a clinical prediction model for occurrence of the post-thrombotic syndrome (PTS) after proximal deep vein thrombosis (DVT), termed the SOX-PTS scor...

The incidence of venous thromboembolism in children following colorectal resection for inflammatory bowel disease: A multi-center study.

Mar 09, 2020

Children with inflammatory bowel disease (IBD) have increased risk for venous thromboembolism (VTE). We sought to determine incidence and risk factors for postoperative VTE in a multicenter cohort of ...

Expert Consensus Statement for the Management of Patients with Embolic Stroke of Undetermined Source and Patent Foramen Ovale: a clinical guide by the Working Group for Stroke of the Hellenic Society of Cardiology and the Hellenic Stroke Organization.

Mar 09, 2020

Patent foramen ovale (PFO) is a frequent echocardiographic finding and can be found in approximately 15-25% of the general population1 (Figure 1). The incidence of PFO is 2- to 3-fold higher in patien...

[Evaluating the long-term prognosis of coronary artery disease patients undergoing percutaneous coronary intervention by risk stratification with ACC/AHA classification of coronary lesions].

Mar 09, 2020

To evaluate the long-term prognosis of coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI) by risk stratification with American College of Cardiology (ACC)/Amer...

Inherited Metabolic Diseases and Cardiac Pathology in Adults: Diagnosis and Prevalence in a CardioMetabo Study.

Mar 09, 2020

Many inherited metabolic diseases (IMD) have cardiac manifestations. The aim of this study was to estimate the prevalence of IMD in adult patients with hypertrophic cardiomyopathy (HCM) and cardiac rh...

Complex Evolution of Epidemiology of Vascular Diseases, Including Increased Disease Burden: From 2000 to 2015.

Mar 09, 2020

Vascular diseases, encompassing coronary heart disease (CHD), cerebrovascular disease (CVD), and peripheral artery disease (PAD), are leading causes of the global mortality and morbidity burdens. Our ...

Percutaneous coronary intervention in aorto-ostial coronary chronic total occlusion: outcomes and technical considerations in a multicenter registry.

Mar 09, 2020

Percutaneous coronary intervention (PCI) for aorto-ostial chronic total coronary occlusion (CTO) can be a particularly challenging lesion subset. The aim of this study was to analyze the technical asp...

Single session of repetitive transcranial magnetic stimulation to left dorsolateral prefrontal cortex increased dual-task gait speed in chronic stroke: A pilot study.

Mar 09, 2020

Individuals with stroke often experience difficulty in dual-task walking and are prone to falling when walking and talking. Previous studies in other populations have suggested that non-invasive brain...

Altered gray matter volumes in post-stroke depressive patients after subcortical stroke.

Mar 09, 2020

Stroke survivors are known to suffer from post-stroke depression (PSD). However, the likelihood of structural changes in the brains of PSD patients has not been explored. This study aims to extract ch...

[Interests and limitations of percutaneous coronary intervention strategy in nonagenarian patients: A single center experience].

Mar 09, 2020

To expose our center results in the angioplasty in nonagenarians and to evaluate its effectiveness but also the MACEs and the mortality in the short and long term.A retrospective study of 98 patients ...

Association Between Hospital Cardiac Catheter Laboratory Status, Use of an Invasive Strategy, and Outcomes After NSTEMI.

Mar 09, 2020

Increased use of invasive coronary strategies in patients admitted to hospitals with on-site cardiac catheter laboratory (CCL) facilities has been reported, but the utilisation of invasive coronary st...