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Cardiology General

The Association of Stage 1 Hypertension Defined by the 2017 ACC/AHA Guideline with Stroke and Its Subtypes among Elderly Chinese.

Mar 12, 2020

The 2017 American College of Cardiology and American Heart Association hypertension guideline updated stage 1 hypertension definition as systolic blood pressure range from 130 to 139 mmHg or diastol...

Meta-analysis of cardiovascular superiority trials published in the to elucidate the concept of superiority margin.

Mar 12, 2020

To show that overpowered trials claim statistical significance detouring clinical relevance and warrant the need of superiority margin to avoid such misinterpretation.Selective review of articles publ...

Remote blood pressure monitoring and behavioral intensification for stroke: A randomized controlled feasibility trial.

Mar 12, 2020

Measuring blood pressure (BP) at home and remote monitoring can improve the patient's adherence to BP control and vascular outcomes. This study evaluated the feasibility of a trial regarding the effec...

Acute insular infarction: Early outcomes of minor stroke with proximal artery occlusion.

Mar 12, 2020

We hypothesized that admission insular infarcts could be associated with early neurological deterioration (END) in acute minor stroke with large vessel occlusion.Using acute and follow-up diffusion-we...

The Association between Aortic Valve Weight, Echocardiographic Indices, and All-Cause Death in 1,046 Patients Undergoing Surgical Aortic Valve Replacement for Aortic Stenosis.

Mar 12, 2020

Aortic valve weight (AVW), a flow independent measure of aortic stenosis (AS) severity, is reported to have heterogeneous associations with the echocardiographic variables used for AS evaluation. Cont...

Priorities for Services in Young Patients With Atherosclerotic Cardiovascular Disease and Their Family Members: An Exploratory Mixed-Methods Study.

Mar 12, 2020

Optimal design of clinical programs for patients with premature atherosclerotic cardiovascular disease (ASCVD) (men aged ≤ 50 years, women aged ≤ 55 years) requires an understanding of their prio...

Genetic Determinants of Myocardial Infarction Risk in Familial Hypercholesterolemia.

Mar 12, 2020

Familial hypercholesterolemia (FH) is an inherited condition of elevated serum low-density lipoprotein (LDL) cholesterol leading to premature coronary heart disease. We evaluated whether FH mutations ...

Low High-Sensitivity Troponin Thresholds Identify Low-Risk Patients With Chest Pain Unlikely to Benefit From Further Risk Stratification.

Mar 12, 2020

Very low high-sensitivity cardiac troponin T (hs-cTnT) thresholds on presentation can rule out acute myocardial infarction (AMI), but the ability to identify patients at low risk of 30-day major adver...

Assessment of quality indicators for acute myocardial infarction management in 28 countries and use of composite quality indicators for benchmarking.

Mar 12, 2020

The European Society of Cardiology established a set of quality indicators for the management of acute myocardial infarction. Our aim was to evaluate their degree of attainment, prognostic value and p...

Comparison of spatial temporal representations of the vectorcardiogram using digital image processing.

Mar 12, 2020

The vectorcardiography (VCG) is a method of representing the heart's electrical activity in three dimensions that is not frequently used in clinical practice due to the higher complexity compared to e...

Association of the Duration of Ideal Cardiovascular Health Through Adulthood With Cardiometabolic Outcomes and Mortality in the Framingham Offspring Study.

Mar 12, 2020

The American Heart Association ideal cardiovascular health (CVH) score is associated with the risk of cardiovascular disease (CVD) and mortality. However, it is unclear whether the number of years spe...

Basement Membrane Remodelling Controls Endothelial Function in IPAH.

Mar 12, 2020

The extracellular matrix (ECM) increasingly emerges as an active driver in several diseases, including idiopathic pulmonary arterial hypertension (IPAH). The basement membrane (BM) is a specialized cl...

Lysine-Specific Demethylase-1 Deficiency Increases Agonist Signaling Via the Mineralocorticoid Receptor.

Mar 12, 2020

LSD1 (lysine-specific demethylase-1) is an epigenetic regulator of gene transcription. LSD1 risk allele in humans and LSD1 deficiency () in mice confer increasing salt-sensitivity of blood pressure wi...

Limited dietary interventions in rural Australian communities: A systematic review.

Mar 12, 2020

This review aimed to synthesise the evidence on the effectiveness of dietary interventions targeting adolescents (>13 years) and adults living in rural or remote Australia.Six electronic databases w...

Astragaloside IV relieves gestational diabetes mellitus in genetic mice through reducing hepatic gluconeogenesis.

Mar 12, 2020

Background The glucose intolerance developed during pregnancy is called gestational diabetes mellitus (GDM). GDM has become a severe risk for the health of both mother and baby. Astragaloside IV (AS-I...

Can injection of adipose stem cells to non-union zone increase bone union? Experimental rat study.

Mar 12, 2020

This study aims to evaluate the effects of local adipose stem cell injection on non-union and diabetic non-union of rat femurs.Forty-eight female Wistar albino rats (weighing mean 200 g and aged 8 wee...

Role of Inflammation on Retinal Microcirculation in Diabetic Eyes: Correlation between Aqueous Flare and Microvascular Findings.

Mar 12, 2020

To investigate the correlation between aqueous flare and macular microvascular status assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus.A cross sectional study was conduct...

The beneficial effects of Agaricus blazei Murrill on hepatic antioxidant enzymes and the pancreatic tissue recovery in streptozotocin-induced diabetic rats.

Mar 12, 2020

Agaricus blazei Murrill (ABM), is a medicinal mushroom, has beneficial effects on diabetes mellitus. In this study, ABM extracts (ethanol extract, EE and ethyl acetate extract, EA) were evaluated to e...

The effect of diet on oxidative stress and metabolic diseases-Clinically controlled trials.

Mar 12, 2020

Oxidative stress is associated with several chronic diseases. It is acknowledged that molecules damaged by reactive oxygen species activate the inflammatory process and that this response increases th...

Use of Electronic Health Records by Older Adults, 85 Years and Older, and Their Caregivers.

Mar 12, 2020

Healthcare providers may not offer patient portal (PP) access to electronic health records (EHRs) to their patients older than 85 years, due to the false impression that they do not utilize technolo...