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Cardiology General

Rupatadine, a dual antagonist of histamine and platelet-activating factor (PAF), attenuates experimentally induced diabetic nephropathy in rats.

Mar 23, 2020

The role of histamine and platelet activating factor (PAF) as involved mediators in the pathophysiology of diabetic complications, in particular diabetic nephropathy (DN), has become a new focus of co...

Renal functional impairment in the elderly, the importance of fasting plasma glucose: the Northern Shanghai Study.

Mar 23, 2020

Chronic kidney disease is a global health problem that is closely related to the aging population. Although plasma glucose levels have been shown to be related to renal dysfunction, risk factors for r...

Glucose Lowering Treatment Modalities of Type 2 Diabetes Mellitus.

Mar 23, 2020

This chapter gives an overview of present knowledge and clinical aspects of antidiabetic drugs according to the recently available research evidence and clinical expertise.Many agents are acting on ei...

Features of cotton wool spots in diabetic retinopathy: a spectral-domain optical coherence tomography angiography study.

Mar 23, 2020

To describe the features of cotton wool spots (CWSs) in diabetic retinopathy (DR) by using spectral-domain optical coherence tomography (SD-OCT) and optical coherence tomography angiography (OCT angio...

The Impact of Sex on Outcomes after Revascularization for Multivessel Coronary Disease.

Mar 23, 2020

Coronary artery disease (CAD) has historically been responsible for more deaths in women than in men and previous studies have suggested sex differences in revascularization approaches and outcomes. W...

Maslinic acid suppresses macrophage foam cells formation: Regulation of monocyte recruitment and macrophage lipids homeostasis.

Mar 23, 2020

The transformation of macrophages to foam cells is a critical component in atherosclerotic lesion formation. Maslinic acid (MA), a novel natural pentacyclic triterpene, has cardioprotective and anti-i...

Inhibition of nuclear factor kappa B as a mechanism of Danshensu during Toll-like receptor 2-triggered inflammation in macrophages.

Mar 23, 2020

Danshensu (DSS) is a water-soluble phenolic compound in Danshen (Salvia Miltiorrhiza Radix et Rhizoma). Although various pharmacological activities have been recognized, little is known regarding its ...

Proportion of High-Risk/Very High-Risk Patients in Europe with Low-Density Lipoprotein Cholesterol at Target According to European Guidelines: A Systematic Review.

Mar 23, 2020

Assess achievement of low-density lipoprotein cholesterol (LDL-C) targets in European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) guidelines.Systematic literature review.Medline...

Migraine Headache and Risk of Dementia in the Atherosclerosis Risk in Communities Neurocognitive Study.

Mar 23, 2020

We aimed to assess the association between migraine headache and incident dementia.Migraine is a risk factor for white matter hyperintensities and ischemic stroke, which are both associated with incre...

Unusual case of antiphospholipid syndrome presenting as adrenal insufficiency.

Mar 20, 2020

A 64-year-old man presented to the emergency department with generalised fatigue and dizzy spells. His background history includes a previous admission with right leg deep vein thrombosis, provoked by...

Experience of a 40-day (6 week) LMWH treatment for isolated distal deep vein thrombosis.

Mar 20, 2020

Clinical significance of distal deep vein thrombosis (DVT) is important as it can potentially result in pulmonary embolism (PE), DVT extension, DVT recurrence and post-thrombotic syndrome (PTS). Contr...

Clinicoradiological Profile of Superficial Middle Cerebral Vein Thrombosis.

Mar 20, 2020

The diagnosis of isolated cortical vein thrombosis (ICVT) involving superficial middle cerebral vein (SMCV) remains challenging even in the present era of modern MRI protocols.The purpose of this stud...

Thrombosis rates using aspirin and a compression device as multimodal prophylaxis for lower limb arthroplasty in a screened population.

Mar 20, 2020

Venous thromboembolism (VTE) (Deep vein thrombosis (DVT), and pulmonary embolism (PE)), is a common complication in patients undergoing total joint arthroplasty (TJA). Recently, aspirin was recommende...

Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation.

Mar 20, 2020

Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults h...

Acute Coronary Syndromes in Chronic Kidney Disease: Clinical and Therapeutic Characteristics.

Mar 20, 2020

This study evaluated the clinical characteristics of the acute coronary syndromes (ACS) in chronic kidney disease (CKD) patients and established prognostic values of the biomarkers and echocardiograp...

EMMPRIN/CD147 plays a detrimental role in clinical and experimental ischemic stroke.

Mar 20, 2020

Ischemic stroke is a devastating disease, often resulting in death or permanent neurological deficits. EMMPRIN/CD147 is a plasma membrane protein that induces the production of matrix metalloproteinas...

Symmetry in the front crawl stroke of different skill level of able-bodied and disabled swimmers.

Mar 20, 2020

Although swimming is recognized as a symmetrical sport, equivalence between each body side cannot be insured. Swimmers with physical and motor impairment may present asymmetries that are even more pro...

Wellens' Syndrome Presenting as Epigastric Pain and Syncope: An Unusual Presentation.

Mar 20, 2020

Wellens' syndrome, also regarded as left anterior descending coronary T-wave syndrome, is an electrocardiography (EKG) pattern that indicates critical proximal left anterior descending artery (LAD) st...

Does Atrial Fibrillation Increase the Risk of Developing End-stage Renal Disease in Patients with Chronic Kidney Disease?

Mar 20, 2020

Patients with atrial fibrillation (AF) have elevated risks of developing stroke, heart failure, and myocardial infarction. However, the impact of AF on the progression of chronic kidney disease (CKD) ...

Effects of Preoperative HbA1c Levels on the Postoperative Outcomes of Coronary Artery Disease Surgical Treatment in Patients with Diabetes Mellitus and Nondiabetic Patients: A Systematic Review and Meta-Analysis.

Mar 20, 2020

To investigate the effect of preoperative HbA1c levels on the postoperative outcomes of coronary artery disease surgery in diabetic and nondiabetic patients.The MEDLINE (via PubMed), Cochrane Library,...