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Cardiology General

The dedicated "Lp(a) clinic": A concept whose time has arrived?

Apr 06, 2020

The emergence of pathophysiological, epidemiologic, and genetic data strongly supports the causality for lipoprotein(a) [Lp(a)] in cardiovascular disease (CVD) and calcific aortic valve disease (CAVD)...

Outcomes of reperfusion therapy for acute ischaemic stroke in patients aged 90 years or older: a retrospective study.

Apr 06, 2020

The benefits and risks of acute reperfusion therapy (RT) in acute ischaemic stroke (AIS) remain uncertain in older patients, especially in nonagenarians. We aimed to assess the impact of RT in this po...

Elevated miR-9 in Cerebrospinal Fluid Is Associated with Poor Functional Outcome After Subarachnoid Hemorrhage.

Apr 06, 2020

This study evaluated microRNA (miRNA) changes in cerebrospinal fluid (CSF) and their association with the occurrence of delayed cerebral ischemia (DCI) and poor functional outcome after SAH. Forty-thr...

Development of a point system to predict discharge to home for acute stroke patients.

Apr 06, 2020

While in an acute hospital setting, it is challenging for clinicians to make discharge decisions due to the multifactorial process and the individual patient characteristics.To evaluate and develop a ...

An Experimental Series Investigating the Effects of Hyperinsulinemic Euglycemia on Myocardial Blood Flow Reserve in Healthy Individuals and on Myocardial Perfusion Defect Size following ST-Segment Elevation Myocardial Infarction.

Apr 06, 2020

Incomplete restoration of myocardial blood flow (MBF) is reported in up to 30% of ST-segment elevation myocardial infarction (STEMI) despite prompt mechanical revascularization. Experimental hyperinsu...

Adverse cardiac events after vascular surgery are prevalent despite negative results of preoperative stress testing.

Apr 06, 2020

Cardiac risk assessment is a critical component of vascular disease management before surgical intervention. The predictive risk reduction of a negative cardiac stress test result remains poorly defin...

Mid-term results after simultaneous carotid artery stenting and cardiac surgery.

Apr 06, 2020

The presence of carotid artery disease is known risk factor for perioperative stroke in cardiac surgery. The optimal management of patients with concomitant heart and carotid artery disease is not kno...

Safety and efficacy of antiplatelet regimens after percutaneous coronary intervention using drug eluting stents: A network meta-analysis of randomized controlled trials.

Apr 06, 2020

We aimed to determine the efficacy and safety of different anti-platelet regimens after percutaneous coronary intervention (PCI) with drug eluting stent (DES) implantation using a network meta-analysi...

Efficacy of continuous positive airway pressure (CPAP) in the prevention of cardiovascular events in patients with obstructive sleep apnea: Systematic review and meta-analysis.

Apr 06, 2020

Obstructive sleep apnea (OSA) commonly occurs in patients with increased cardiovascular (CV) risk, and continuous positive airway pressure (CPAP) is the preferred therapy for these patients. The aim o...

Patients with atrial fibrillation and mid-range ejection fraction differ in anticoagulation pattern, thrombotic and mortality risk independently of CHADS-VAS score.

Apr 06, 2020

Atrial fibrillation (AF) patients with mid-range left ventricular ejection fraction (mrEF) of 40-49% have neither preserved (pEF > 50%) nor reduced (rEF ...

Influence of long-standing pulmonary arterial hypertension and its severity on pulmonary artery aneurysm development.

Apr 06, 2020

Pulmonary artery aneurysm (PAA) is a common finding in patients with long-term pulmonary arterial hypertension (PAH). The influence of PAH severity in the development of PAA remains unclear. We sought...

CARD9 promotes autophagy in cardiomyocytes in myocardial ischemia/reperfusion injury via interacting with Rubicon directly.

Apr 06, 2020

Autophagy in cardiomyocyte is involved in myocardial ischemia/reperfusion (M-I/R) injury. Caspase recruitment domain-containing protein 9 (CARD9) plays a critical role in cardiovascular diseases (CVDs...

Factors associated with early phosphate levels in preterm infants.

Apr 06, 2020

To investigate perinatal factors and early morbidities associated with early serum phosphate (sPhos) levels in a cohort of preterm infants. Retrospective data were obtained from the medical records of...

Comparison and analyses of therapeutic effects between metabolic management center (MMC) and conventional management modes.

Apr 06, 2020

The past 3 decades witnessed the rapid growth of diabetes in China. To better serve large numbers of patients, the Chinese Medical Doctor Association launched metabolic management center (MMC) progra...

Clinical evidence regarding factors linking metabolic abnormal obesity to pancreatic beta cell dysfunction.

Apr 06, 2020

In the past few decades, the prevalence of obesity has increased not only in Western countries but also in Asia. Obesity is frequently accompanied by unhealthy adipocyte expansion; this results in a c...

Interactions between ocular and systemic disease using national register-based data in the Danish Excellence Centre in Ophthalmic Epidemiology (DECODE-EYE): study perspective.

Apr 06, 2020

The Danish Excellence Centre in Ophthalmic Epidemiology (DECODE-EYE) is a national research collaboration formed in order to study the real-life interaction between ocular and systemic disease based o...

Controversial aspects of testosterone in the regulation of sexual function in late onset hypogonadism.

Apr 06, 2020

Testosterone (T) plays a pivotal role in coordinating a series of psychological, cognitive and physical events that might (or might not) culminate in male sexual activity. In fact, T deficiency is ass...

Metformin revert insulin-induced oxaliplatin resistance by activating mitochondrial apoptosis pathway in human colon cancer HCT116 cells.

Apr 06, 2020

Several studies have suggested that drug resistance in colon cancer patients with diabetes may be associated with long-term insulin administration, which in turn decreases the survival rate. Metformin...

O-water positron emission tomography of myocardial ischemia in patients referred for percutaneous coronary intervention.

Apr 06, 2020

The diagnostic accuracy of non-invasive diagnostic methods for detecting coronary artery disease has increased in recent years. This study aimed to assess the diagnostic performance of O-water positro...

Complications in the adult asplenic patient: A review for the emergency clinician.

Apr 06, 2020

The spleen performs several important physiologic functions. However, patients can have functional asplenia or have their spleen removed for a number of reasons, which can put them at risk for several...