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Cardiology General

Predicting Functional Outcome Based on Linked Data After Acute Ischemic Stroke: S-SMART Score.

Apr 20, 2020

Prediction of outcome after stroke may help clinicians provide effective management and plan long-term care. We aimed to develop and validate a score for predicting good functional outcome available f...

Daily high-dose aspirin does not lower APRI in the Aspirin-Myocardial Infarction Study.

Apr 20, 2020

Antiplatelet agents reduce liver fibrosis by inhibiting platelet activation and platelet-derived growth factor production. Previous cross-sectional epidemiological studies suggest that the use of aspi...

Extracellular matrix-based biomaterials for cardiac regeneration and repair.

Apr 20, 2020

The spectrum of ischemic heart diseases, encompassing acute myocardial infarction to heart failure, represents the leading cause of death worldwide. Although extensive progress in cardiovascular diagn...

Increased Myocardial Retention of Mesenchymal Stem Cells Post-MI by Pre-Conditioning Exercise Training.

Apr 20, 2020

Stem cell (SC) therapy is a promising approach to improve post-myocardial infarction (MI) cardiac remodeling, but the proinflammatory microenvironment may lead to SC loss and, therefore, may have a ne...

The Positive Effects of a Calorie-Restricting High-Protein Diet Combined with Intragastric Botulinum Toxin Type A Application Among Morbidly Obese Patients: A Prospective, Observational Analysis of Eighty-Seven Grade 2 Obese Patients.

Apr 20, 2020

Many studies evaluating the effect of intragastric botulinum toxin type A injection (IG-BTxA) for the treatment of obesity have been published. However, none of these studies combined this procedure w...

Hematopoietic cell infusion-related adverse events in pediatric/small recipients in a prospective/multicenter study.

Apr 20, 2020

Hematopoietic cell infusion-related adverse events (HCI-AEs) in hematopoietic stem cell transplantations (HSCTs) have been largely attributed to toxicity of dimethyl sulfoxide (DMSO) for cryopreservat...

Age and sex-specific reference ranges are needed for the Aldosterone/Renin Ratio.

Apr 20, 2020

Current Endocrine Society Clinical Practice Guidelines use a specific aldosterone/renin ratio (ARR) threshold to screen for primary aldosteronism (a treatable disease causing up to 15% of hypertension...

The Impact of Bariatric Surgery on Hepatic Function and Predictors of Liver Steatosis and Fibrosis.

Apr 20, 2020

To evaluate the variation in parameters of hepatic function and in the scores Fatty Liver Index (FLI; predictor of hepatic steatosis) and BARD (BMI, AST/ALT ratio and DM, predictor of hepatic fibrosis...

Prognosis of patients eligible for dapagliflozin in acute heart failure.

Apr 20, 2020

Dapagliflozin, a sodium-glucose cotransporter 2 inhibitor, was shown in the DAPA-HF study to reduce the risk of worsening heart failure or death in symptomatic patients with left ejection fraction < 4...

Pharmacological screening of fenofibrate-loaded solid dispersion in fructose-induced diabetic rat.

Apr 20, 2020

Hyperlipidaemia is a common phenomenon in diabetes mellitus. Fenofibrate (FF) is a good candidate for the treatment of lipid abnormalities in patients with type 2 diabetes. But the bioavailability as ...

The association between anti-insulin aspart antibodies and the pharmacokinetic and pharmacodynamic characteristics of fast-acting insulin aspart in children and adolescents with type 1 diabetes.

Apr 20, 2020

Fast-acting insulin aspart (faster aspart) is a novel formulation of insulin aspart (IAsp) ensuring ultra-fast absorption and effect.To compare the pharmacokinetics between faster aspart and IAsp, bas...

Comorbidities in the Elderly and Their Possible Influence on Vaccine Response.

Apr 20, 2020

The following chapter is focused on the impact of comorbidities on the effectiveness of vaccination in older persons. Relevant comorbidities are cardiovascular diseases like hypertension, coronary art...

Midregional pro atrial natriuretic peptide: a novel important biomarker for noise annoyance-induced cardiovascular morbidity and mortality?

Apr 20, 2020

Environmental noise exposure has been associated with increased cardiovascular morbidity and mortality. Recently, noise annoyance was shown to induce atrial fibrillation, which was accompanied by sign...

Healthcare utilization and cost of care in elderly breast cancer patients enrolled in SWOG clinical trials.

Apr 20, 2020

Patients with cancer are at risk for unplanned hospitalizations during treatment which can increase the cost of care.To determine demographic and clinical factors associated with healthcare utilizatio...

Predictors for layered coronary plaques: an optical coherence tomography study.

Apr 20, 2020

Healed coronary plaques, morphologically characterized by a layered pattern, are signatures of previous plaque disruption and healing. Recent optical coherence tomography (OCT) studies showed that lay...

Prolonged Therapeutic Effects of Photoactivated Adipose-derived Stem Cells following Ischemic Injury.

Apr 20, 2020

Adipose-derived stem cells (ASCs) therapies are emerging as a promising approach to therapeutic angiogenesis. Therapeutic persistence and reduced primitive stem cell function following cell delivery...

Canada-wide mixed methods analysis evaluating the reasons for inappropriate emergency department presentation in patients with a history of atrial fibrillation: the multicentre AF-ED trial.

Apr 20, 2020

The primary objective of this study was to ascertain the reasons for emergency department (ED) attendance among patients with a history of atrial fibrillation (AF).Appropriate ED attendance was define...

Use of Temporary Mechanical Circulatory Support for Management of Cardiogenic Shock Before and After the United Network for Organ Sharing Donor Heart Allocation System Changes.

Apr 20, 2020

The new United Network for Organ Sharing (UNOS) donor heart allocation system gives priority to patients supported with nondischargeable mechanical circulatory support (MCS) devices while awaiting hea...

Controlling antibiotic usage - A national analysis of General Practitioner/Family Doctor (GP/FD) practices links overall antibiotic levels to demography, geography, comorbidity factors with local discretionary prescribing choices.

Apr 20, 2020

Ecological studies show association between antimicrobial resistance (AMR), and inappropriate oral antibiotics use. Moderating antibiotic prescribing requires an understanding of all drivers of local ...

Cardiovascular disease among people living with HIV in Brazil.

Apr 20, 2020

There is a paucity of data on cardiovascular disease (CVD) among people living with HIV (PLHIV) in resource-limited countries. We assessed factors associated with CVD and the impact of prevalent CVD o...