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Cardiology General

Spinal or general anaesthesia for surgical repair of hip fracture and subsequent risk of mortality and morbidity: a database analysis using propensity score-matching.

Apr 28, 2020

Around 76,000 people fracture their hip annually in the UK at a considerable personal, social and financial cost. Despite longstanding debate, the optimal mode of anaesthesia (general or spinal) remai...

Obesity in adolescent men increases the risk of venous thromboembolism in adult life.

Apr 28, 2020

As the population of obese and severely obese young adults grows, it is becoming increasingly important to recognize the long-term risks associated with adolescent obesity.This study aimed to determin...

Use of a biopsy punch for end-to-side anastomosis in free-tissue transfer.

Apr 28, 2020

In end-to-side vessel-anastomoses, a side fenestration should be made by a slit incision or partial excision of the vessel wall. However, a slit incision might restrict blood flow across the anastomo...

Cuba's Role in International Atomic Energy Agency Regional Cooperation in Cardiology.

Apr 28, 2020

Cardiovascular diseases are the leading cause of death worldwide, and a health problem in low- and middle-income as well as high-income countries. They also constitute the main cause of death in Latin...

Complexity of aortic arch anatomy affects the outcomes of transcarotid artery revascularization versus transfemoral carotid artery stenting.

Apr 28, 2020

Transcarotid artery revascularization (TCAR) has been shown to have half the rates of transient ischemic attack (TIA), stroke and death compared to transfemoral carotid artery stenting (TFCAS). Succes...

Incidence and prognostic factors for recurrence of intracerebral hemorrhage in patients with and without atrial fibrillation: A cohort study.

Apr 28, 2020

Intracerebral hemorrhage is a devastating vascular event. Clinical factors prognostic of recurrence facilitating individualized post-bleeding patient management are sparsely described. We aimed to des...

Elderly Patients With Cervical Spine Fractures After Ground Level Falls Are at Risk for Blunt Cerebrovascular Injury.

Apr 28, 2020

Osteopenia is common in the elderly, increasing their risk of sustaining cervical fractures after ground level falls (GLFs). We sought to examine the incidence of blunt cerebrovascular injury (BCVI) a...

Implantable loop recorder monitoring in patients with cryptogenic stroke - Detection and treatment of different clinically relevant arrhythmias.

Apr 28, 2020

Implantable loop recorders (ILR) are recommended to detect atrial fibrillation (AF) in cases of cryptogenic stroke. However, real life data besides controlled trials are rare. Aim of the study was the...

Limited fascicle shortening and fascicle rotation may be associated with impaired voluntary force-generating capacity in pennate muscles of chronic stroke survivors.

Apr 28, 2020

Muscle weakness is one of the most common motor impairments after stroke. A variety of progressive muscular changes are reported in chronic stroke survivors, and it is now feasible to consider these c...

Factor Xa inhibitors in patients with continuous-flow left ventricular assist devices.

Apr 28, 2020

Warfarin is standard anticoagulation therapy for patients with a continuous-flow left ventricular assist device (CF-LVAD). However, warfarin requires regular monitoring and dosage adjustments and fail...

A Novel Anti-Coagulative Nanocomplex in Delivering miRNA-1 Inhibitor Against Microvascular Obstruction of Myocardial Infarction.

Apr 28, 2020

Great progress has been made in miRNA nanodelivery for the treatment of myocardial infarction (MI). However, miRNA nanodelivery within the infarct is impeded by microvascular obstruction as a local ci...

Effect of P2Y12 inhibitor monotherapy versus dual antiplatelet therapy on cardiovascular events in patients undergoing percutaneous coronary intervention: systematic review and meta-analysis.

Apr 28, 2020

Clinical data on short mandatory dual antiplatelet therapy (DAPT) followed by P2Y12 inhibitor monotherapy, compared with prolonged DAPT in patients undergoing percutaneous coronary intervention (PCI) ...

Long-term Graft Patency after Off-Pump and On-Pump Coronary Artery Bypass: A CORONARY Trial Cohort.

Apr 28, 2020

Randomized controlled trials have compared the early and mid-term prognosis of on-pump coronary artery bypass grafting (CABG) and off-pump CABG. However, the results are controversial, and there is li...

Supra-coronary Aortic Banding Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension in Rats by Increasing Systolic Right Coronary Artery Perfusion.

Apr 28, 2020

Pulmonary arterial hypertension (PAH) results in right ventricular (RV) dysfunction due, in part, to RV ischemia. The relative contribution of RV microvascular rarefaction versus reduced right coronar...

Imperatorin: A review of its pharmacology, toxicity and pharmacokinetics.

Apr 28, 2020

As a naturally occurring furanocoumarin, the medicinal value of imperatorin has been studied more and more. We hope to provide useful information for the further development of imperatorin by analyzin...

Short- and long-term outcomes following biological pericardium patches versus prosthetic patches for carotid endarterectomy: A retrospective bicentric study.

Apr 28, 2020

Currently, there are various types of patches available on the market for carotid endarterectomy (CEA) with enlargement angioplasty, prosthetic and biological patches including bovine pericardial patc...

Predicting Optimal Hypertension Treatment Pathways Using Recurrent Neural Networks.

Apr 28, 2020

In ambulatory care settings, physicians largely rely on clinical guidelines and guideline-based clinical decision support (CDS) systems to make decisions on hypertension treatment. However, current cl...

Astragaloside IV acts through multi-scale mechanisms to effectively reduce diabetic nephropathy.

Apr 28, 2020

Diabetic nephropathy (DN), a common complication of diabetes mellitus, is the main cause of end-stage nephropathy, and thus developing novel strategies for reversing DN remains urgent. Astragaloside I...

Mechanisms of putative IGF-I receptor resistance in active acromegaly.

Apr 28, 2020

Acromegaly is a disease characterized by overproduction of growth hormone (GH). As a consequence of excessive GH secretion, circulating insulin-like growth factor-I (IGF-I) is elevated in active (untr...

Oral health and halitosis among Type 1 diabetic and healthy children.

Apr 28, 2020

To evaluate the oral health status, oral health related habits and halitosis of children with and without type 1 diabetes.In this study oral health status of children with and without type 1 diabetes ...