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Cardiology General

Antiplatelet and Anticoagulant Risk for Select Spine Interventions: A Retrospective Cohort.

May 05, 2020

To identify significant bleeding complications following spinal interventions in patients taking medications with antiplatelet or anticoagulation effect.Retrospective chart review of a 12-month period...

Endovascular balloon occlusion during reconstruction of portal vein injury.

May 05, 2020

Repair of portal vein injury in a hostile abdomen can be very challenging, complicated by massive hemorrhage or stenosis. It can seldom be successfully carried out, even by experienced hepatobiliary s...

Calf deep vein thrombosis - clinical relevance, diagnostic approaches and therapeutic options.

May 05, 2020

Isolated distal deep vein thromboses (IDDVT) represent up to 50 % of legs deep vein thromboses (DVT). However, since their natural history is to date unknown, the need to diagnose and treat them is ...

Wearables in cardiology: Here to stay.

May 05, 2020

The adoption of wearables in medicine has rapidly expanded worldwide. New generations of wearables are emerging, driven by consumers' demand to monitor their own health. With the ongoing development o...

Mitral Valve Surgery via a Right Infra-axillary Thoracotomy in High-Risk Reoperative Patients.

May 05, 2020

A right infra-axillary thoracotomy can offer excellent exposure of the mitral valve. This study evaluated this incision for high-risk patients undergoing redo mitral valve procedures.Of a series of 18...

Contribution of oxygen extraction fraction to maximal oxygen uptake in healthy young men.

May 05, 2020

We analysed the importance of systemic and peripheral arteriovenous O difference (a- O and a-v O difference, respectively) and O extraction fraction for maximal oxygen uptake ( O ). Fick law of diff...

Growth differentiation factor-11 supplementation improves survival and promotes recovery after ischemic stroke in aged mice.

May 05, 2020

Growth differentiation factor (GDF) 11 levels decline with aging. The age-related loss of GDF 11 has been implicated in the pathogenesis of a variety of age-related diseases. GDF11 supplementation rev...

Partnering With Patients to Bridge Gaps in Consent for Acute Care Research.

May 05, 2020

Clinical trials for acute conditions such as myocardial infarction and stroke pose challenges related to informed consent due to time limitations, stress, and severe illness. Consent processes should ...

Acute and One-year Clinical Outcomes of Pre-stenting Intravascular Ultrasound: A Patient-level Meta-analysis of Randomised Clinical Trials.

May 05, 2020

To investigate the association of pre-stenting intravascular ultrasound (IVUS) evaluation on procedural and clinical outcomes for diffuse lesions treated with drug-eluting stent (DES).In four randomis...

Stress cardiomyopathy misinterpreted as ST-segment elevation myocardial infarction in a patient with aneurysmal subarachnoid hemorrhage: a case report.

May 05, 2020

Cardiac abnormalities are frequently reported in acute subarachnoid hemorrhage (SAH) patients. However, frank ST-elevation and myocardial dysfunction mimicking acute coronary syndrome is a rare occurr...

Characterization of a porcine model of atrial arrhythmogenicity in the context of ischaemic heart failure.

May 05, 2020

Atrial fibrillation (AF) is a major healthcare challenge contributing to high morbidity and mortality. Treatment options are still limited, mainly due to insufficient understanding of the underlying p...

Bleeding risk of ticagrelor compared to clopidogrel in intensive care unit patients with acute coronary syndrome: A propensity-score matching analysis.

May 05, 2020

Intensive care unit (ICU) patients with the most severe forms of acute coronary syndrome (ACS) require invasive therapies such as extracorporeal life support. The risk of bleeding in ICU patients with...

Epidemiologic study in a real-world analysis of patients with treatment for psoriasis in the French national health insurance database.

May 05, 2020

Psoriasis is one of the most frequent chronic inflammatory dermatoses in the world. Data on the prevalence of psoriasis in adults differ depending on the study.To estimate the prevalence of patients w...

Tricuspid Regurgitation in Ostium Secundum Atrial Septal Defects: Repair or Not?

May 05, 2020

Longstanding ostium secundum atrial septal defects lead to functional tricuspid regurgitation. Significant functional tricuspid regurgitation associated with left heart valve disease is addressed at t...

Overexpression of METTL3 attenuates high-glucose induced RPE cell pyroptosis by regulating miR-25-3p/PTEN/Akt signaling cascade through DGCR8.

May 05, 2020

Methyltransferase-like protein 3 (METTL3) regulates multiple cell functions and diseases by modulating N-methyladenosine (mA) modifications. However, it is still unclear whether METTL3 involves in the...

Association of handgrip strength with the prevalence of metabolic syndrome in US adults: the national health and nutrition examination survey.

May 05, 2020

Aimed to find the cut-off point of handgrip strength and it's association with MetS.The relative handgrip strength was negatively associated with the prevalence of MetS. Of note, the odds ratios (ORs)...

Hepatic Slug epigenetically promotes liver lipogenesis, fatty liver disease, and type 2 diabetes.

May 05, 2020

De novo lipogenesis is tightly regulated by insulin and nutritional signals to maintain metabolic homeostasis. Excessive lipogenesis induces lipotoxicity, leading to nonalcoholic fatty liver disease (...

Evaluation of biochemical profile of Chronic Kidney Disease of uncertain etiology in Sri Lanka.

May 05, 2020

Chronic Kidney Disease of uncertain etiology (CKDu) is an endemic, disease that mostly affects young agricultural workers in the rural dry zone of Sri Lanka. This study was designed to identify specif...

On using electronic health records to improve optimal treatment rules in randomized trials.

May 05, 2020

Individualized treatment rules (ITRs) tailor medical treatments according to patient-specific characteristics in order to optimize patient outcomes. Data from randomized controlled trials (RCTs) are u...

Endurance Exercise in Seniors: Tonic, Toxin or Neither?

May 05, 2020

Cardiac adaptation to sustained exercise in the athletes is established. However, exercise-associated effect on the cardiac function of the elderly has to be elucidated. The aim of this study was to a...