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Cardiology General

Isovaleroylbinankadsurin A ameliorates cardiac ischemia/reperfusion injury through activating GR dependent RISK signaling.

May 19, 2020

Ischemia/reperfusion (I/R) injury is a pathological process caused by reperfusion. The prevention of I/R injury is of great importance as it would enhance the efficacy of myocardial infarction treatme...

The association between road traffic noise and myocardial infarction: A systematic review and meta-analysis.

May 19, 2020

This systematic review and meta-analysis study aimed to investigate the association between exposure to road traffic noise (RTN) and myocardial infarction (MI). Of 681 studies found by searching in da...

MCT2 overexpression rescues metabolic vulnerability and protects retinal ganglion cells in two models of glaucoma.

May 19, 2020

Improving cellular access to energy substrates is one strategy to overcome observed declines in energy production and utilization in the aged and pathologic central nervous system. Monocarboxylate tra...

A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF.

May 19, 2020

The metabolic syndrome and associated comorbidities, like diabetes, hypertension and obesity, have been implicated in the development of heart failure with preserved ejection fraction (HFpEF). The mol...

ACEI/ARB Use and Risk of Infection or Severity or Mortality of COVID-19: A Systematic Review and Meta-analysis.

May 19, 2020

We have sparse knowledge of the effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) on the risk of COVID-19 infection and the progression of this disea...

Update in Pediatric Pseudotumor Cerebri Syndrome.

May 19, 2020

Pseudotumor cerebri syndrome (PTCS) is a rare condition in children presenting with headache and papilledema from increased intracranial pressure that can cause significant morbidity. This can be idio...

Inadequate achievement of ABC goals (HbA1c, blood pressure, LDL-C) among patients with type 2 diabetes in an Iranian population, 2012-2017.

May 19, 2020

This study was designed to evaluate the meeting of ABC goals in patients with type 2 diabetes. The ABC goals were defined as meeting the HbA1c ...

Gender differences in the risk factors for high and very high blood glucose levels: A study of Kerala.

May 19, 2020

Worldwide, lifestyle is a significant risk factor for diabetes. Lifestyle changes can lead to differences in the extent of risk of diabetes among women and men. Kerala, a state with one of the best he...

Polysaccharides from Opuntia milpa alta alleviate alloxan-induced INS-1 cells apoptosis via reducing oxidative stress and upregulating Nrf2 expression.

May 19, 2020

The incidence and progression of type 2 diabetes are closely related to pancreatic β-cell damage. Oxidative stress may be one of the key factors contributing to β-cell apoptosis. Opuntia milpa alta ...

Interleukin-6 trans-signaling inhibition prevents oxidative stress in a mouse model of early diabetic retinopathy.

May 19, 2020

Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading cause of visual disability and blindness in diabetic patients. Chronic hyperglycemia leads to increased oxidative st...

Demographic Characteristics Among Patients With Chronic Exertional Compartment Syndrome of the Lower Leg.

May 19, 2020

Clinical Scenario: Chronic exertional compartment syndrome (CECS) is a condition related with ischemia of the body's tissue due to increases in intracompartmental pressures, which involves, among othe...

Compelling indications should be listed for individual beta-blockers (due to diversity), not for the whole class.

May 19, 2020

Introduction Beta blockers (BBs) are an important class of drugs, with numerous indications in cardiology, emergency and general medicine. The indications include heart failure (HF), acute myocardial ...

Maternal hypercholesterolemia during pregnancy: Potential modulation of cholesterol transport through the human placenta and lipoprotein profile in maternal and neonatal circulation.

May 19, 2020

During pregnancy, there is a progressive increase in the levels of maternal cholesterol, a lipid that is essential for foetal growth and development. This increase can occur in a physiological (MPH) o...

Is triglyceride associated with adult depressive symptoms? A big sample cross-sectional study from the rural areas of central China.

May 19, 2020

Previous studies have produced contradictive results on the association between serum lipids and depressive symptoms. The present study aimed to examine the association between serum lipids and depres...

Diagnostic Accuracy of Early Computed Tomographic Coronary Angiography to Detect Coronary Artery Disease After Out-of-Hospital Circulatory Arrest.

May 19, 2020

To test the diagnostic accuracy of ECG-gated coronary computed tomography angiography (CCTA) to detect coronary artery disease (CAD) among survivors of out-of-hospital circulatory arrest (OHCA).We pro...

CT calcification patterns of peripheral arteries in patients without known peripheral arterial disease.

May 19, 2020

In the last few years histologic studies of peripheral arteries have shown that both intimal and medial calcifications are found in patients in an early, asymptomatic stage and that differentiation be...

Investigation of the Effect of HATCH Score and Coronary Artery Disease Complexity on Atrial Fibrillation After On-Pump Coronary Artery Bypass Graft Surgery.

May 19, 2020

Postoperative atrial fibrillation (PoAF) is the most frequently encountered rhythm problem after coronary artery bypass graft (CABG) operations. This situation decreases the capacity of the patients f...

Assessment of atrial conduction time by Doppler tissue imaging in hypertensive patients.

May 19, 2020

Hypertension is the first cause of atrial fibrillation. Its onset is explained by intricate mechanisms such as atrial conduction impairment.To evaluate atrial conduction by tissue Doppler imaging in h...

Concordance and Discordance of Echocardiographic Parameters Recommended for Assessing the Severity of Mitral Regurgitation.

May 19, 2020

The American College of Cardiology/American Heart Association and American Society of Echocardiography guidelines recommend assessing several echocardiographic parameters when evaluating mitral regurg...

Left Ventricular Ejection Fraction Is Associated with the Risk of Thrombus in the Left Atrial Appendage in Patients with Atrial Fibrillation.

May 19, 2020

Atrial fibrillation (AF) is associated with high risk of ischemic stroke. The most frequent thrombus location in AF is the left atrial appendage (LAA). Transthoracic echocardiography (TTE) is a basic ...