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Cardiology General

Covid-19: Cardiac Arrhythmias Linked to Systemic Illness, Not Solely SARS-CoV-2

Jun 25, 2020

Critically ill patients 10 times more likely to develop arrhythmia Among Covid-19 patients admitted to a large academic hospital, those admitted to ICUs were 10 times more likely than other patient...

Comparison of pathological clotting using haematological, functional and morphological investigations in HIV-positive and HIV-negative patients with deep vein thrombosis.

Jun 25, 2020

Patients infected with the human immunodeficiency virus (HIV) are more prone to systemic inflammation and pathological clotting, and many may develop deep vein thrombosis (DVT) as a result of this dys...

High incidence of venous thromboembolism and major bleeding in patients with primary CNS lymphoma.

Jun 25, 2020

Venous thromboembolism (VTE) and major bleeding in primary central nervous system lymphoma (PCNSL) patients are not well described. We identified 992 PCNSL patients using the California Cancer Registr...

Pharmacologic thromboprophylaxis in adult patients undergoing neurosurgical interventions for preventing venous thromboembolism.

Jun 25, 2020

The impact of pharmacologic prophylaxis for venous thromboembolism in patients undergoing neurosurgical intervention remains uncertain. We reviewed the efficacy and safety of pharmacologic compared wi...

The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan.

Jun 25, 2020

Humanin is a member of a new family of peptides that are encoded by short open reading frames within the mitochondrial genome. It is conserved in animals and is both neuroprotective and cytoprotective...

Effect of Intraoperative Dexamethasone on Major Complications and Mortality Among Infants Undergoing Cardiac Surgery: The DECISION Randomized Clinical Trial.

Jun 25, 2020

Corticosteroids are widely used in pediatric cardiac surgery to blunt systemic inflammatory response and to reduce complications; nevertheless, their clinical efficacy is uncertain.To determine whethe...

Exogenous IL-4 shuts off pro-inflammation in neutrophils while stimulating anti-inflammation in macrophages to induce neutrophil phagocytosis following myocardial infarction.

Jun 25, 2020

Macrophages and neutrophils are primary leukocytes involved in the inflammatory response to myocardial infarction (MI). While interleukin (IL)-4 is an in vitro anti-inflammatory stimulus, the MI myoca...

Sevoflurane as opposed to propofol anesthesia preserves mitochondrial function and alleviates myocardial ischemia/reperfusion injury.

Jun 25, 2020

Pharmacological interventions reducing myocardial ischemia and reperfusion (I/R) injury include the administration of anesthetics. Both sevoflurane as well as propofol have been shown to elicit cardia...

Clinical characteristics of older and younger patients infected with SARS-CoV-2.

Jun 25, 2020

SARS-CoV-2 causes high mortality risk in older patients. This study aims to characterize the clinical features of older and younger SARS-CoV-2 infected patients.A total of 239 patients were divided in...

Fibroblast Growth Factor 21 and Metabolic Dysfunction in Women with a Prior Glucose-Intolerant Pregnancy.

Jun 25, 2020

 We sought to determine if there is an association between fibroblast growth factor 21 (FGF21) levels and a history of gestational diabetes mellitus (GDM) in women with and without metabolic dysfunc...

Analysis of spontaneous, user-generated data about gestational diabetes on online forums: implications for diabetes prevention.

Jun 25, 2020

To explore the experiences and perceptions of gestational diabetes mellitus reported by women within online parental-support forums and, specifically, to analyse what women say about a diagnosis of ge...

Probiotic treatment for women with gestational diabetes to improve maternal and infant health and well-being.

Jun 25, 2020

Gestational diabetes mellitus (GDM) is carbohydrate intolerance first recognised during pregnancy and associated with complications for mothers and babies. Probiotics are naturally occurring micro-org...

Furosemide use in Italian neonatal intensive care units: a national survey.

Jun 25, 2020

Furosemide is approved in full term neonates to treat edema associated with congestive heart failure, cirrhosis and renal diseases. It is often administered off-label in premature neonates, to treat r...

The NO-donor MPC-1011 stimulates angiogenesis and arteriogenesis and improves hindlimb ischemia via a cGMP-dependent pathway involving VEGF and SDF-1α.

Jun 25, 2020

Peripheral arterial disease (PAD) is an important cause of morbidity and mortality with little effective medical treatment currently available. Nitric oxide (NO) is crucially involved in organ perfusi...

Tolerogenic vaccines for the treatment of cardiovascular diseases.

Jun 25, 2020

Atherosclerosis is the main pathology behind most cardiovascular diseases. It is a chronic inflammatory disease characterized by the formation of lipid-rich plaques in arteries. Atherosclerotic plaque...

Small rodent models of atherosclerosis.

Jun 25, 2020

The ease of breeding, low cost of maintenance, and relatively short period for developing atherosclerosis make rodents ideal for atherosclerosis research. However, none of the current models accuratel...

[Atrial flutter in cardiology practice].

Jun 25, 2020

Atrial flutter (AFL) is one of the most common arrhythmias present in clinical practice, both for the GPs and cardiologist practice. After atrial fibrillation (AF) is second the most common supraventr...

Risk factors for 2019 novel coronavirus disease (COVID-19) patients progressing to critical illness: a systematic review and meta-analysis.

Jun 25, 2020

With the rising number of COVID-19 cases, global health resources are strained by the pandemic. No proven effective therapies or vaccines for this virus are currently available. In order to maximize t...

Higher risk of dementia in English older individuals who are overweight or obese.

Jun 25, 2020

Several risk factors contribute to dementia, but the role of obesity remains unclear. This study investigated whether increased body weight or central obesity were associated with a higher risk of dev...

An International Survey on the Use of Thromboprophylaxis in Urological Surgery.

Jun 22, 2020

The use of perioperative thromboprophylaxis in urological surgery is common but not standardized.To characterize international practice variation in thromboprophylaxis use in urological surgery.We con...