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Cardiology General

The ABO Locus is Associated with Increased Fibrin Network Formation in Patients with Stable Coronary Artery Disease.

Jul 02, 2020

 The locus has been associated with increased risk of myocardial infarction (MI) in patients with coronary artery disease (CAD), but the underlying mechanisms are unknown. As altered fibrin clot st...

Detection of arrhythmia using an implantable cardiac monitor following a cryptogenic stroke: a single-center observational study.

Jul 02, 2020

Detection of atrial fibrillation (AF) after cryptogenic stroke (CS) has therapeutic implications, but the most effective type and optimal duration of monitoring have still to be defined. This study th...

Oral Anticoagulants for Non-Valvular Atrial Fibrillation In Frail Elderly Patients: Insights from the ARISTOPHANES Study.

Jul 02, 2020

Patient frailty among patients with non-valvular atrial fibrillation (NVAF) is associated with adverse health outcomes and increased risk of mortality. Additional evidence is needed to evaluate effect...

Atrial Fibrillation and Mitral Regurgitation: Clinical Performance of Direct Oral Anticoagulants in a Real-World Setting.

Jul 02, 2020

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is frequently present in patients with mitral regurgitation (MR). Currently, there is a lack of real-world evidence specifically addr...

Gender & Migraine Mortality

Jun 30, 2020

Prior research indicates that women with migraine are at an increased risk of cardiovascular disease-related mortality, when compared with women without migraine. However, studies assessing whether mi...

Successful secondary thromboprophylaxis with direct oral anticoagulants for a patient with catastrophic antiphospholipid syndrome: A case report.

Jun 29, 2020

Catastrophic antiphospholipid syndrome (CAPS) is a rare, life-threatening condition of antiphospholipid syndrome (APS). Treatment and management of CAPS remain challenging and the mortality rate is ap...

The complication trends of adult spinal deformity surgery in Japan - The Japanese Scoliosis Society Morbidity and Mortality survey from 2012 to 2017.

Jun 29, 2020

The Japanese Scoliosis Society Morbidity & Mortality Committee performed a longitudinal nationwide complication survey of spinal deformity surgery from 2012 to 2017. The present study aimed to ana...

Effect of Concomitant Deep Venous Reflux on Truncal Endovenous Ablation Outcomes in the Vascular Quality Initiative.

Jun 29, 2020

Few studies have investigated outcomes following truncal endovenous ablation in patients with combined deep and superficial reflux and no studies have evaluated patient-reported outcomes.We investigat...

Time trends and patient selection in the use of continuous ECG for detecting atrial fibrillation after stroke: a nationwide cohort study.

Jun 29, 2020

Clinical use of continuous electrocardiogram (cECG) for detecting atrial fibrillation (AF) after stroke is unclear. In a Danish nationwide cohort we described post-stroke time trends in outpatient cEC...

Impact of lesion preparation strategies on outcomes of left main PCI: The EXCEL trial.

Jun 29, 2020

We examined outcomes according to lesion preparation strategy (LPS) in patients with left main coronary artery (LMCA) percutaneous coronary intervention (PCI) in the EXCEL trial.The optimal LPS for LM...

The Importance of Considering Both Primary and Secondary Diagnostic Codes When Using Administrative Health Data to Study Acute Coronary Syndrome Epidemiology (ANZACS-QI 47).

Jun 29, 2020

Routinely collected health administrative data has become an important data source for investigators assessing disease epidemiology. Our aim was to investigate the implications of identifying acute co...

MicroRNAs in the regulation of cellular redox status and its implications in myocardial ischemia-reperfusion injury.

Jun 29, 2020

MicroRNAs (miRNAs) are small RNAs that do not encode for proteins and play key roles in the regulation of gene expression. miRNAs are involved in a comprehensive range of biological processes such as ...

Added prognostic value of longitudinal changes of angiogenic factors in early-onset severe preeclampsia: a prospective cohort study.

Jun 29, 2020

To assess in women with early-onset severe preeclampsia whether longitudinal changes in angiogenic factors improve the prediction of adverse outcome.Prospective cohort study.Maternity units in two Spa...

[Prevalence and features of geriatric syndromes treatment in old patients (clinical and epidemiological study).]

Jun 29, 2020

We studied the prevalence of chronic non-communicable diseases (CND) in elderly and senile patients in conjunction with the syndrome of senile asthenia, the prevalence of sarcopenia depending on gende...

SGLT2 inhibitors reduce day-to-day glucose variability in patients with type 1 diabetes.

Jun 29, 2020

SGLT2 inhibitors (SGLT2i) are used worldwide because of their multiple benefits for patients with type 2 diabetes. The purpose of this study was to determine the efficacy and safety of SGLT2i in patie...

Prevalence and risk factors of potentially prescribing omissions in elderly and senile patients: clinical practice in Russian hospitals.

Jun 29, 2020

A retrospective pharmacoepidemiological study (included data from medical records of 401 patients ≥65 years of age who received treatment in hospitals) was aimed to measure prevalence of potentially...

[Benefits of androgen replacement therapy and audio-visual correction inclusion in the prevention of premature aging.]

Jun 29, 2020

There are changes in the metabolism, reproductive and nervous systems with ageing, which have a systemic and interrelated nature. The purpose of this work was to demonstrate the effectiveness of audio...

Macrophage polarisation associated with atherosclerosis differentially affects their capacity to handle lipids.

Jun 29, 2020

Lipid-rich foam cell macrophages drive atherosclerosis via several mechanisms, including inflammation, lipid uptake, lipid deposition and plaque vulnerability. The atheroma environment shapes macropha...

Cyanidin-3-O-glucoside attenuates endothelial cell dysfunction by modulating miR-204-5p/SIRT1-mediated inflammation and apoptosis.

Jun 29, 2020

Endothelial cell (EC) dysfunction is a major symptom associated with the initiation of atherosclerosis (AS). Cyanidin-3-O-glucoside (C3G) has the potentials to attenuate AS symptoms. In the current st...

Serum Soluble ST2 is a Potential Long-term Prognostic Biomarker for Transient Ischaemic Attack and Ischaemic Stroke.

Jun 29, 2020

Soluble ST2 (sST2) is a promising biomarker in inflammation, atherosclerosis, and cardiovascular diseases. We investigated the association between serum sST2 and poor outcome in patients with transien...