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Cardiology General

Effect of a dianthin G analogue in the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes.

Aug 03, 2020

Loss of cardiomyocytes due to myocardial infarction results in ventricular remodeling which includes non-contractile scar formation, which can lead to heart failure. Stem cell therapy aims to replace ...

Late-onset hypogonadism: reductio ad absurdum of the cardiovascular risk-benefit of testosterone replacement therapy.

Aug 03, 2020

Low testosterone (T) level is considered a marker of poor cardiovascular health. Ten years ago, the Testosterone in Older Men with Mobility Limitations (TOM) trial was discontinued due to a higher num...

Outcomes of Pulmonary Endarterectomy Operation Concomitant with Cardiac Procedures.

Aug 03, 2020

 The aim of this study was to analyze the results of pulmonary endarterectomy (PEA) performed simultaneously with additional cardiac procedures in a single tertiary-level center. Data of patients ...

First-line pazopanib in intermediate- and poor-risk patients with metastatic renal cell carcinoma: Final results of the FLIPPER trial.

Aug 03, 2020

Temsirolimus has long been the only approved first-line standard-of-care (SOC) with overall survival (OS) benefit in poor-risk patients with advanced or metastatic renal cell cancer (mRCC). However, t...

Dietary fiber intake and risk of type 2 diabetes in a general Japanese population: the Hisayama Study.

Aug 03, 2020

The investigation of the influence of the dietary fiber intake on the incidence of type 2 diabetes in a general Japanese population.A total of 1,892 subjects aged 40-79 years without diabetes at basel...

Metabolic syndrome in type 1 diabetes and its association with diabetes complications.

Aug 03, 2020

To assess the prevalence of metabolic syndrome in type 1 diabetes, and its age-related association with diabetes complications.Australian National Diabetes Information Audit and Benchmarking (ANDIAB) ...

Prevalence of Latent and Overt Polyautoimmunity in Autoimmune Thyroid Disease: A Systematic Review and Meta-analysis.

Aug 03, 2020

Thyroid autoimmunity is the most frequent condition involved in polyautoimmunity (PolyA). However, the frequency of latent and overt PolyA in patients with autoimmune thyroid disease (AITD) as the ind...

Screening for regional contractile defaults to predict the delayed Doxorubicin Cardiotoxicity in Juvenile Rat.

Aug 03, 2020

Anthracyclines are key chemotherapeutic agents used in various adult and pediatric cancers, however, their clinical use is limited due to possible congestive heart failure (HF) caused by acute and irr...

Sesquiterpene lactone Zaluzanin D alters MMP-9 promoter methylation in differentiated THP-1 monocytic cells and down regulates inflammatory cytokines IL-1β and TNF-α.

Aug 03, 2020

Zaluzanin D (ZD) is a sesquiterpene lactone isolated from the leaves of Vernonia arborea. Earlier studies have highlighted the Sesquiterpene lactones (SLs) as molecules of medicinal value. The current...

Urinary heavy metals, DNA methylation, and subclinical atherosclerosis.

Aug 03, 2020

Lead (Pb) or cadmium (Cd) exposure has been linked to atherosclerosis. Co-exposure of these two heavy metals often occurs in humans. Recent evidence has indicated a crucial role of DNA methylation in ...

Numerical computation of blood hemodynamic through constricted human left coronary artery: Pulsatile simulations.

Aug 03, 2020

The accumulation of plaque in the coronary artery of the human heart restricts the path of blood flow in that region and leads to Coronary Artery Disease. This study's goal is to present the pulsatile...

Real-Life Incident Atrial Fibrillation in Outpatients with Coronary Artery Disease.

Aug 03, 2020

The risk, correlates, and consequences of incident atrial fibrillation (AF) in patients with chronic coronary artery disease (CAD) are largely unknown. We analyzed incident AF during a 3-year follow...

Practice Gap in Atrial Fibrillation Oral Anticoagulation Prescribing at Emergency Department Home Discharge.

Aug 03, 2020

Current U.S. cardiology guidelines recommend oral anticoagulation (OAC) to reduce stroke risk in selected patients with atrial fibrillation (AF), but no formal AF OAC recommendations exist to guide em...

Heart Failure, Cardiac Injury May be Next Chapter in Covid-19

Jul 31, 2020

Two studies raise new concerns about long-term cardiac injury Two newly published studies raise concerns about lasting myocardial injury and heart failure related to Covid-19 infection. An analysi...

Chocolate Tied to Lower Coronary Artery Disease Risk

Jul 30, 2020

THURSDAY, July 30, 2020 (HealthDay News) -- Eating chocolate at least once a week is associated with a lower risk for coronary artery disease (CAD), according to a review published online July 22 in t...

Should we prevent thrombosis related to intravenous immunoglobulin infusions with systematic anticoagulant prophylaxis?

Jul 30, 2020

Intravenous immunoglobulins (IVIg) are commonly used for treatment of dysimmune diseases, but they are known to promote thrombotic events. The medical records of patients who received IVIg infusions t...

Similarities and Differences Between Primary Percutaneous Coronary Intervention and Mechanical Thrombectomy.

Jul 30, 2020

Acute ischemic stroke is among the leading causes of mortality and disability worldwide. Since 2015, as was the case for primary percutaneous coronary intervention for acute myocardial infarction, cat...

Isolated Diastolic Hypertension in the UK Biobank: Comparison of ACC/AHA and ESC/NICE Guideline Definitions.

Jul 30, 2020

The 2017 American College of Cardiology/American Heart Association guideline defines hypertension as a blood pressure ≥130/80 mm Hg, whereas the 2018 European Society of Cardiology (ESC) and 2019 Na...

Mechanical thrombectomy using the new Tigertriever in acute ischemic stroke patients - A Swiss prospective multicenter study.

Jul 30, 2020

Tigertriever is a novel operator-adjustable clot retriever designed to enhance the operator's options to control the interaction of retriever and clot. The aim of this study was to assess the feasibil...

Enabling Better Use of Person-Generated Health Data in Stroke Rehabilitation Systems: Systematic Development of Design Heuristics.

Jul 30, 2020

An established and well-known method for usability assessment of various human-computer interaction technologies is called heuristic evaluation (HE). HE has been adopted for evaluations in a wide vari...