Aug 06, 2020

Atherosclerosis is a systemic chronic inflammatory disease. Many antioxidants including alpha-lipoic acid (LA), a product of lipoic acid synthase (Lias), have proven to be effective for treatment of t...

Aug 06, 2020

Myocardial infarction with nonobstructive coronary arteries (MINOCA) remains a puzzling clinical entity that is characterized by clinical evidence of myocardial infarction (MI) with normal or near-nor...

Aug 06, 2020

Atherosclerosis (AS) is the main cause of myocardial infarction and stroke. Macrophage apoptosis in the early stages can attenuate lesions, while in the late stage it is associated with AS plaque rupt...

Aug 06, 2020

Adherence to guidelines was not homogeneous in Europe, according to the survey on cardiac resynchronization therapy conducted in 2008-2009. The aim of our study was to compare the results in the Itali...

Aug 06, 2020

Conducting a clinical trial involves significant risks, time, and resources. The return on investment for these trials, measured by advancing health care and contributions to the scientific literature...

Aug 06, 2020

Bioprosthetic mitral valves are implanted with increasing frequency but inevitably degenerate, leading to heart failure. Reoperation is associated with high morbidity and mortality. Transcatheter mitr...

Aug 06, 2020

The role of stress cardiac magnetic resonance (CMR) imaging in clinical decision-making by reclassification of risk across American College of Cardiology/American Heart Association guideline-recommend...

Aug 05, 2020

ASCVD calculator underestimates risk in some young adults A substantial proportion of younger patients who had myocardial infarction (MI) did not meet recommendations for primary prevention statin th...

Aug 04, 2020

Post-hoc analysis of PARAGON-HF biomarker data provides clues When sacubitril/valsartan was tested in persons with preserved ejection fraction heart failure (HFpEF) in the PARAGON-HF trial, the initi...

Aug 04, 2020

One temperature will not ’fit’ every post cardiac arrest patient Is there an ideal core body temperature to improve survival in patients who are comatose following cardiac arrest? A study...

Aug 03, 2020

Risks seen even with short treatment duration In patients with first myocardial infarction (MI), prescription non-steroidal anti-inflammatory drug (NSAID) treatment over a mean follow-up of 2.3 years...

Aug 03, 2020

Bilateral adrenal hemorrhage is a rare condition with potentially life-threatening consequences as acute adrenal insufficiency. Early adrenal axis testing, as well as directed imaging, is crucial for ...

Aug 03, 2020

A reversal agent for factor Xa (FXa) inhibitors, andexanet alfa, was FDA approved without extensive study of clinical effectiveness, due to an overwhelming demand for FXa inhibitor reversal. In this s...

Aug 03, 2020

The objective of this study was to investigate the clinical utility of D-dimer in excluding a diagnosis of deep vein thrombosis (DVT) in patients with COVID-19 infection, potentially limiting the need...

Aug 03, 2020

Cardiovascular disease (CVD) is the primary cause of death in the developed-countries and mostly in the poorer areas of the country, and in lower income-groups.Birthweight predicts adult development o...

Aug 03, 2020

To compare patient-level risk assessment at Veterans Affairs (VA) hospitals in patients undergoing transcatheter aortic valve replacement (TAVR) with patients included in the Society for Thoracic Surg...

Aug 03, 2020

While a nursing intervention program for immobile patients with stroke can improve clinic outcomes, less is known about the cost-effectiveness of these interventions.The goal of this study was to eval...

Aug 03, 2020

Delirium, the clinical expression of acute encephalopathy, is a common neuropsychiatric syndrome that is related to poor outcomes, such as long-term cognitive impairment. Disturbances of functional br...

Aug 03, 2020

This paper aims at examining the clinical characteristics of ischemic stroke patients with different levels of pre-stroke functional dependency, their long-term outcome, and determinants of five-year ...

Aug 03, 2020

To examine the effects of holiday and weekend admission on in-hospital mortality for patients with acute myocardial infarction (AMI) in China.Patients with AMI in 31 tertiary hospitals in Shanxi, Chin...