Aug 10, 2020

External controls have been primarily used in the setting of single-arm trials of rare diseases; their use in common diseases has not been readily investigated, nor is there guidance on how to best se...

Aug 10, 2020

Delirium is an acute disturbance characterized by fluctuating symptoms related to attention, awareness and recognition. Especially for elderly patients, delirium is frequently associated with high hos...

Aug 10, 2020

This is a case report of a 60-year-old male, without any cardiovascular risk factor and no cardiac history admitted to hospital with a diagnosis of interstitial pneumonia caused by coronavirus disease...

Aug 10, 2020

The chronopharmacology refers to the utilization of physiological circadian rhythms to optimize the administration time of drugs, thus increasing their efficacy and safety, or reducing adverse effects...

Aug 10, 2020

Peripheral arterial disease (PAD) affects more than 200 million people worldwide. Recent studies suggest that oxidative stress-related inflammation can lead to the initiation and progression of PAD. F...

Aug 10, 2020

The 2018 American Heart Association/American College of Cardiology (AHA/ACC) cholesterol management guidelines identified 2 distinct groups of patients with atherosclerotic cardiovascular disease (ASC...

Aug 10, 2020

Regional South Australia has some of the highest rates of psychological distress, chronic disease and multimorbidity of any Australian State or Territory. Yet, the healthcare needs of this population ...

Aug 10, 2020

Ticagrelor improves clinical outcomes in patients with acute myocardial infarction (AMI). This study aimed to compare the efficacy and safety of ticagrelor versus clopidogrel in East Asian patients wi...

Aug 09, 2020

With emerging data suggesting that therapies for type 2 diabetes mellitus (T2DM) can impact outcomes among patients with heart failure (HF), and vice versa, but no single document that comprehensively...

Aug 07, 2020

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are one of the drugs used in the treatment of type-2 diabetes. However, a recent study associated the use of SGLT 2 inhibitor with the increased risk ...

Aug 07, 2020

Migraine is a neurovascular headache disorder. The consequential effects of migraine headaches are unclear, but few studies have linked migraine in pregnant women with an increased risk of maternal st...

Aug 07, 2020

The incidence of Ischemic heart disease and stroke depends significantly on a diet. This study aims to examine the associations of meat, fish, and a vegetarian diet with the risk of ischemic heart dis...

Aug 07, 2020

More than 30% of people with a new stroke remain impaired in activities of daily living. Some recent studies have indicated improvements in speed and physical strength after physical fitness training ...

Aug 07, 2020

There are a plethora of established studies that have established the link between obesity and cardiovascular disease (CVD). But the effects of maternal obesity on the cardiovascular health of offspri...

Aug 07, 2020

Recent trials have evaluated the use of aspirin to prevent stroke after an ischemic stroke or transient ischemic attack (TIA). While ticagrelor alone is not better than aspirin in preventing vascular ...

Aug 07, 2020

There have been rising acute safety concerns regarding certain hemorrhage-sparing medications in cardiac surgery. The objective of this study is to contrast long-term all-cause mortality in patients u...

Aug 07, 2020

Lipoprotein (a) is a causal genetic risk factor for atherosclerotic cardiovascular disease. But it remains unclear which patients with underlying atherosclerotic cardiovascular disease tend to benefit...

Aug 07, 2020

Prediabetes or intermediate hyperglycemia is a high-risk metabolic state of diabetes. Some recent cohort studies indicate that prediabetes is associated with a higher risk of atherosclerotic cardiovas...

Aug 07, 2020

One of the early signs of loss of immune control over adenovirus is the fecal shedding of adenovirus following allogeneic hematopoietic stem-cell transplantation (HSTC). The objective of this research...

Aug 07, 2020

Cardiovascular diseases are one of the leading causes of cause-specific mortality across the globe. Many believe that people with increased intake of fats and carbohydrates are at a higher risk of dev...