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Cardiology General

First in human evaluation of a novel Sirolimus-eluting ultra-high molecular weight bioresorbable scaffold: 9-, 24-and 36-months imaging and clinical results from the multi-center RENASCENT study.

Aug 20, 2020

RENASCENT is a prospective, multi-center first-in-human clinical study to evaluate the clinical performance of the novel sirolimus-eluting 150-μm strut thickness FORTITUDE® BRS for percutaneous coro...

Management and outcomes of uncomplicated ST-segment elevation myocardial infarction patients transferred after fibrinolytic therapy.

Aug 20, 2020

This study sought to assess the contemporary outcomes of patients transferred after receiving fibrinolytic therapy ('drip-and-ship') for ST-segment elevation myocardial infarction (STEMI) in the Unite...

Pseudotumor Cerebri Syndrome (PTCS) with Different Types of Hormonal Contraceptives in Women of Child-Bearing Age.

Aug 20, 2020

Comparative safety data on the risk of pseudotumor cerebri syndrome (PTCS) with different hormonal contraceptives is absent. We sought to quantify the risk of PTCS with eight different types of hormon...

Higher Risk of Urinary Tract Infections in Renal Transplant Recipients Receiving Pentamidine Versus Trimethoprim-Sulfamethoxazole (TMP-SMX) for Pneumocystis Pneumonia Prophylaxis.

Aug 20, 2020

Urinary tract infection (UTI) is one of the most common infectious complications among renal transplant patients. Trimethoprim-sulfamethoxazole (TMP-SMX) is routinely used as first-line prophylaxis ag...

Liver steatosis is highly prevalent and is associated with metabolic risk factors and liver fibrosis in adult patients with type 1 Gaucher disease.

Aug 20, 2020

Gaucher disease (GD) is associated with peculiar metabolic abnormalities (i.e. hypermetabolic state, peripheral insulin resistance, dyslipidemia), partially reverted by enzyme replacement therapy (ERT...

Health-related quality of life 90 days after stroke assessed by the International Consortium for Health Outcome Measurement (ICHOM) standard set.

Aug 20, 2020

Stroke has detrimental effects in multiple health domains not captured by routine scales. The International Consortium for Health Outcome Measurement has developed a standardized set for self-reported...

A comprehensive review on miR-146a molecular mechanisms in a wide spectrum of immune and non-immune inflammatory diseases.

Aug 20, 2020

MicroRNAs (miRNAs) are single-strand endogenous and non-coding RNA molecules with a length of about 22 nucleotides, which regulate genes expression, through modulating the translation and stability of...

Highly Conserved Amino Acid Residues in Apolipoprotein A1 Discordantly Induce High Density Lipoprotein Assembly In Vitro and In Vivo.

Aug 20, 2020

Apolipoprotein A1 (APOA1) is essential to reverse cholesterol transport, a physiologically important process that protects against atherosclerotic cardiovascular disease. APOA1 is a 28 kDa protein com...

Comparation of The Effects of Losartan, Captopril, Angiotensin II Type 2 Receptor Agonist Compound 21 and MAS Receptor Agonist AVE 0991 on Myocardial Ischemia-Reperfusion Necrosis in Rats.

Aug 20, 2020

Myocardial ischemia may occur as a result of pathophysiological and therapeutical applications such as atherosclerosis, thromboembolism, percutaneous transluminal coronary angioplasty, coronary artery...

Primary Prevention Implantable Cardioverter Defibrillators in Hypertrophic Cardiomyopathy - Are There Predictors of Appropriate Therapy?

Aug 20, 2020

Identifying hypertrophic cardiomyopathy (HCM) patients who warrant a primary-prevention implantable cardioverter defibrillator(ICD) is crucial. ICDs are effective in terminating life-threatening arrhy...

Chrysanthemum zawadskil Herbich attenuates dexamethasone-induced muscle atrophy through the regulation of proteostasis and mitochondrial function.

Aug 19, 2020

Chrysanthemum zawadskii Herbich (CZH) is used in traditional medicine to treat inflammatory diseases and diabetes. However, the effects of CZH on muscle wasting remains to be studied. Here, we investi...

Diclofenac Use and Cardiovascular Risks

Aug 18, 2020

Diclofenac is a nonsteroidal anti-inflammatory drug prescribed to treat painful conditions and inflammatory diseases, like gout. One of the rare side effects of using diclofenac is the risk of cardiov...

Sex Differences and Risk Factors of Myocardial Infarction

Aug 18, 2020

Myocardial infarction (MI) is one of the most common heart diseases that occur in both men and women. But if the risk factors of MI are associated with sex differences is unclear. This study aims to e...

Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients

Aug 18, 2020

Heart and lungs from hepatitis C viremia (HCV)-infected donors are not transplanted, but the rise of direct-acting antiviral agents for HCV has raised the possibility of safe transplants. The objectiv...

The Effects of Antibody-Based Ticagrelor Reversal Agent

Aug 18, 2020

Ticagrelor is a P2Y12 inhibitor drug used in the prevention of stroke, ischemia, heart attack, and other cardiovascular events in people with the acute coronary syndrome. One of the major concerns wit...

Long-term Outcomes of Total vs. Non-Total Arterial Revascularization

Aug 18, 2020

Both total and non-total arterial revascularizations (AR) are used to improve short- and long-term mortality in patients with coronary artery bypass grafting (CABG). However, the long-term outcomes of...

Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

Aug 18, 2020

Type-2 diabetes is associated with a higher risk of cardiovascular events. Recent evidence suggests the safety of oral semaglutide in improving cardiovascular outcomes in patients with type-2 diabetes...

Antithrombotic therapy for arterial fibrillation with stable coronary disease

Aug 18, 2020

Stable coronary disease is often associated with an increased risk of arterial fibrillation. Antithrombotic therapy is one of the treatments in patients with arterial fibrillation, but the results are...

Ticagrelor in patients with diabetes mellitus and stable coronary disease

Aug 18, 2020

Patients with diabetes mellitus and stable coronary disease are at higher risk of cardiovascular events, like stroke or myocardial infarction. Ticagrelor-aspirin combination is known to reduce the ris...

Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation

Aug 17, 2020

Arterial fibrillation is a condition of irregular, rapid heart rate that occurs when the two upper chambers of the heart experience chaotic electrical signals. Immediate restoration of sinus rhythm us...