Sep 03, 2020

We describe the presenting characteristics and hospital course of 11 novel coronavirus (COVID-19) patients who developed spontaneous subcutaneous emphysema (SE) with or without pneumomediastinum (SPM)...

Sep 03, 2020

Excessive alcohol use is an important component of a person's risk for drug overdose death. But alcohol's contribution to overdose death risk has not been well quantified. We aimed to quantify the rol...

Sep 03, 2020

Novel coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread, affecting >10 million cases worldwide. Caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prim...

Sep 03, 2020

Obesity and diabetes are major public health problems. Current approaches to weight loss show varying success. Complex community-based interventions work through several interconnected stages. An indi...

Sep 03, 2020

Approximately half of patients with ST-segment elevation myocardial infarction (STEMI) present with non-infarct related multivessel coronary artery disease (CAD) during primary percutaneous coronary i...

Sep 03, 2020

About half of patients with acute ST-segment elevation myocardial infarction (STEMI) present with multivessel coronary artery disease (MVD). Recent evidence supports complete revascularization in thes...

Sep 03, 2020

Atherosclerosis is characterized by the formation of lipid plaques within the arterial wall. In such plaques, the massive and continuous recruitment of circulating monocyte-derived macrophages induces...

Sep 03, 2020

Despite recent advances in catheter ablation for atrial fibrillation (AF), pulmonary vein reconnection (PVR), and AF recurrence remain significantly high. Ablation index (AI) is a new method incorpora...

Sep 02, 2020

Acute exacerbations of chronic obstructive pulmonary disease (COPD) refer to a condition of sudden worsening of COPD symptoms, including shortness of breath or color of phlegm. Several studies have su...

Sep 02, 2020

Myocardial infarction (MI), also known as heart attack, is a condition that occurs when blood flow decreases or stops to a part of the heart. Colchicine is a potent inflammatory medication routinely u...

Sep 02, 2020

Excessive alcohol consumption is associated with an increased risk of atrial fibrillation and adverse atrial remodeling. However, abstinence from alcohol and the effect on the risk of incident atrial ...

Sep 02, 2020

Heterozygous familial hypercholesterolemia is a disorder characterized by an increased level of LDL cholesterol, resulting in an increased risk of premature atherosclerotic cardiovascular disease. Inc...

Sep 02, 2020

Transcatheter Aortic-Valve Implantation (TAVI) is one of the newly discovered minimally invasive procedure to replace a narrowed aortic valve in patients with aortic valve stenosis. Clopidogrel is an ...

Sep 01, 2020

Vericiguat is one of the routine medications given to patients with heart failure and reduced ejection fraction. However, the effect, efficacy, and safety of the vericiguat are not well studied. The o...

Sep 01, 2020

Peripheral artery disease (PAD) is a circulatory condition characterized by narrow arteries, resulting in reduced blood flow to the limbs. Patients who have undergone revascularization are at higher r...

Sep 01, 2020

Renin-angiotensin-aldosterone system (RAAS) inhibitors include angiotensin-converting enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARBs), and direct renin inhibitors. They act by inhibiting...

Sep 01, 2020

Implantable cardioverter-defibrillator (ICD) is an implantable device inside the body that helps with cardioversion, defibrillation, and pacing of the heart. The use of subcutaneous ICD is on the rise...

Sep 01, 2020

Recurring cellulitis is a recurrently occurring serious bacterial skin infection that usually affects the lower legs. Compression therapy is a technique of increasing blood flow activity in the lower ...

Sep 01, 2020

Homozygous familial hypercholesterolemia is a cardiovascular condition that makes it difficult for the body to remove LDL cholesterol (bad cholesterol) from the blood. Evinacumab is a monoclonal antib...

Aug 31, 2020

Many orthopedic surgeons decline to perform total knee arthroplasty on patients for whom the use of blood components are not an option due to the perceived risk of acute blood loss-related anemia and ...