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Cardiology General

Correlation between Post-Procedure Residual Thrombus and Clinical Outcome in Deep Vein Thrombosis Patients Receiving Pharmacomechanical Thrombolysis in a Multi-center Randomized Trial.

Sep 21, 2020

To evaluate relationships between immediate venographic results and clinical outcomes of pharmacomechanical catheter-directed thrombolysis (PCDT).Venograms from 317 patients with acute proximal deep v...

Short- and long-term outcomes for single-port risk-reducing salpingo-oophorectomy with and without hysterectomy for women at risk for gynecologic cancer.

Sep 21, 2020

Risk-reducing salpingo-oophorectomy has been established as one of the most effective strategies in risk reduction for ovarian and breast cancers among women at increased genetic risk. However, there ...

Difficulty in managing nephrotic syndrome-associated cerebral venous thrombosis.

Sep 21, 2020

Thromboembolism is one of the most serious complications of nephrotic syndrome (NS). Although the occurrence of renal vein thrombosis or deep vein thrombosis is well recognized in NS patients, they ra...

Contribution of individual components to composite endpoints in contemporary cardiovascular randomized controlled trials.

Sep 21, 2020

Cardiovascular randomized controlled trials (RCTs) typically set composite endpoints as the primary outcome to enhance statistical power. However, influence of individual component endpoints on overal...

Implications of NADPH oxidase 5 in vascular diseases.

Sep 21, 2020

Oxidative stress is one of the main mechanisms involved in the pathophysiology of vascular diseases. Among others, oxidative stress promotes endothelial dysfunction, and accelerated ageing and remodel...

Hospital attendance and admission trends for cardiac diseases during the COVID-19 outbreak and lockdown in Greece.

Sep 21, 2020

The coronavirus disease 2019 (COVID-19) outbreak, along with implementation of lockdown and strict public movement restrictions, in Greece has affected hospital visits and admissions. We aimed to inve...

The incidence of thrombotic events with idarucizumab and andexanet alfa: A systematic review and meta-analysis.

Sep 21, 2020

Direct thrombin inhibitor, dabigatran and factor Xa inhibitors, apixaban, edoxaban, and rivaroxaban (DOACs/NOACs), are currently the first-choice drugs in some indications. Life-threatening bleeding o...

Histopathologic Features of Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins with Atypical Clinical Presentation.

Sep 21, 2020

Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is a rare neonatal lung disease with fatal outcome. Typically, respiratory symptoms present in the first 24 hours of life an...

Usefulness of collagen type IV in the detection of significant liver fibrosis in Nonalcoholic Fatty Liver Disease.

Sep 21, 2020

Liver fibrosis assessment is a key issue in the evaluation of nonalcoholic fatty liver disease (NAFLD) patients. In the present study we aimed to validate a noninvasive marker panel to assess signific...

A high-protein meal does not improve blood pressure or vasoactive biomarker responses to acute exercise in humans.

Sep 21, 2020

Blood pressure (BP) responses to exercise yield prognostic information beyond resting BP. While habitual higher dietary protein intake is associated with reduced resting BP, few studies have assessed ...

Non-communicable diseases in Lebanon: results from World Health Organization STEPS survey 2017.

Sep 21, 2020

Non-communicable diseases (NCDs) are a major global health problem. The objective of the study was to estimate the prevalence of common risk factors for NCDs in Lebanon, both among the Lebanese popula...

Probiotic-enriched milk and dairy products increase gut microbiota diversity: a comparative study.

Sep 21, 2020

Targeting gut microbiota with probiotics has emerged as a promising nutritional approach for the prevention of obesity and metabolic syndrome. Cultured dairy products can be effectively employed for t...

Underuse of oral anticoagulants in privately insured patients with atrial fibrillation: A population being targeted by the IMplementation of a randomized controlled trial to imProve treatment with oral AntiCoagulanTs in patients with Atrial Fibrillation (IMPACT-AFib).

Sep 21, 2020

Many studies showing underuse of oral anticoagulants (OACs) in patients with atrial fibrillation (AF) predated the advent of the non-vitamin K antagonist OACs. We retrospectively examined use of OACs ...

Common APOC3 variants are associated with circulating ApoC-III and VLDL cholesterol but not with total apolipoprotein B and coronary artery disease.

Sep 21, 2020

Very rare loss-of-function mutations in the apolipoprotein C3 (APOC3) gene have been associated with low circulating apoC-III, low triglycerides, and reduced cardiovascular risk. We aimed to analyze t...

Deletion of NoxO1 limits atherosclerosis development in female mice.

Sep 21, 2020

Oxidative stress is a risk factor for atherosclerosis. NADPH oxidases of the Nox family produce ROS but their contribution to atherosclerosis development is less clear. Nox2 promotes and Nox4 rather l...

IL17RA in early-onset coronary artery disease: Total leukocyte transcript analysis and promoter polymorphism (rs4819554) association.

Sep 21, 2020

The interleukin-17 (IL-17) pathway would play an important role in the pathogenesis of atherosclerosis and coronary-artery disease (CAD). The IL-17 inflammatory mediators are expressed by Th17 cells, ...

Atrial fibrillation, anticoagulation management and risk of stroke in the Cardiomyopathy/Myocarditis registry of the EURObservational Research Programme of the European Society of Cardiology.

Sep 21, 2020

Cardiomyopathies are a heterogeneous group of disorders that increase the risk for atrial fibrillation (AF). The aim of the study is to assess the prevalence of AF, anticoagulation management, and ris...

The counterintuitive role of exercise in the prevention and cause of atrial fibrillation.

Sep 21, 2020

Atrial fibrillation (AF) is the most common cardiac arrhythmia characterised by irregular atrial activity. AF is related to increased risk of thromboembolic events, heart failure, and premature mortal...

Remote Optimization of Guideline-Directed Medical Therapy in Patients With Heart Failure With Reduced Ejection Fraction.

Sep 21, 2020

Optimal treatment of heart failure with reduced ejection fraction (HFrEF) is scripted by treatment guidelines, but many eligible patients do not receive guideline-directed medical therapy (GDMT) in cl...

Pulmonary vein thrombosis and cerebral infarction after video-assisted thoracic surgery of the left upper lobe: a case series.

Sep 17, 2020

Pulmonary vein thrombosis (PVT) and cerebral infarction are rare but critical complications after video-assisted thoracic surgery (VATS).We experienced two cases of massive middle cerebral artery infa...