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Cardiology General

Complications and Management of the Thoracic Endovascular Aortic Repair.

Nov 09, 2020

Endovascular treatment in thoracic aortic diseases has increased in use exponentially since Dake and colleagues first described the use of a home-made transluminal endovascular graft on 13 patients wi...

Clinical Practice Variation and Outcomes for Stanford Type A Aortic Dissection Repair Surgery in Maryland: Report from a Statewide Quality Initiative.

Nov 09, 2020

 Stanford Type A aortic dissection repair surgery is associated with high mortality and clinical practice remains variable among hospitals. Few studies have examined statewide practice variation. ...

Impact of ischemic risk factors on long-term outcomes in patients with and without high bleeding risk.

Nov 09, 2020

Background The current guidelines have recommended to shorten the dual antiplatelet therapy duration in patients at high bleeding risk (HBR) to minimize the bleeding complications. The impact of ische...

Association between the E-wave propagation index and left ventricular thrombus formation after ST-elevation myocardial infarction.

Nov 09, 2020

To explore the association between E-wave propagation index (EPI) as a marker of apical washout and the risk of left ventricular thrombus (LVT) formation in patients with ST-elevation myocardial infar...

The Role of Public Health Versus Invasive Coronary Interventions in the Decline of Coronary Heart Disease Mortality.

Nov 09, 2020

There has been considerable debate on the extent to which the decline in coronary heart disease (CHD) mortality has been caused by better control of coronary risk factors in the general population or ...

PDE5 inhibition improves cardiac morphology and function in SHR by reducing NHE1 activity: Repurposing sildenafil for the treatment of hypertensive cardiac hypertrophy.

Nov 09, 2020

Previously, we have shown that an increased cGMP-activated protein Kinase (PKG) activity after phosphodiesterase 5 (PDE5) inhibition by Sildenafil (SIL), leads to myocardial Na/H exchanger (NHE1) inhi...

Downregulation of Interferon regulatory factor 7 is link to pulmonary vascular smooth muscle cell proliferation and inflammation in Monocrotaline-induced pulmonary hypertension in rats.

Nov 09, 2020

Interferon regulatory factor 7 (IRF7) plays a key role to regulate an inflammatory response, inhibits vascular smooth cell proliferation and promotes apoptosis. But its role in pulmonary hypertension ...

Postmortem fatal and non-fatal concentrations of amlodipine.

Nov 09, 2020

Amlodipine is a dihydropyridine calcium channel blocker widely used in the treatment of high blood pressure and coronary heart disease. Intoxication can lead to reflex tachycardia following massive hy...

Photobiomodulation reduces hepatic lipogenesis and enhances insulin sensitivity through activation of CaMKKβ/AMPK signaling pathway.

Nov 09, 2020

Photobiomodulation (PBM) could improve systemic blood glucose and insulin resistance in diet-induced diabetic mice. A few possible molecular mechanisms for the beneficial effects of PBM on diabetes ha...

Associations of urinary concentrations of phthalate metabolites, bisphenol A, and parabens with obesity and diabetes mellitus in a Korean adult population: Korean National Environmental Health Survey (KoNEHS) 2015-2017.

Nov 09, 2020

Phthalates and bisphenol A (BPA) have been suspected as risk factors for obesity and diabetes mellitus (DM) among humans. However, associations between phthalates and environmental phenols are often i...

Baroreflex sensitivity with different lags and random forests for staging cardiovascular autonomic neuropathy in subjects with diabetes.

Nov 09, 2020

Impaired baroreflex sensitivity (BRS) may indicate cardiovascular autonomic neuropathy (CAN), which often remains undiagnosed during the initial course of diabetes mellitus. The baroreflex mechanism c...

Non-traditional factors affecting referral for coronary angiography following SPECT myocardial perfusion imaging.

Nov 09, 2020

The use of myocardial perfusion imaging (MPI) in the management of coronary artery disease (CAD) is well established. Although prior studies have shown disparities in the use of invasive angiography i...

Peripheral arterial disease has a strong impact on cardiovascular outcome in patients with acute coronary syndromes: From the START antiplatelet registry.

Nov 09, 2020

Peripheral arterial disease (PAD) was reported to increase the risk of new cardiovascular events in patients with acute coronary syndromes (ACS). However, most of the evidence comes from randomized cl...

Drimys winteri and Isodrimeninol decreased foam cell formation in THP-1 derived macrophages.

Nov 09, 2020

Early stages of atherosclerosis are characterizated for the uptake of oxidate low-density lipoprotein (oxLDL) by inflammatory macrophages in the arteries, promoting the foam cell formation. Drimys win...

EXPRESS: Multiple biomarkers measurement to estimate the duration of atrial fibrillation.

Nov 09, 2020

An accurate estimation of the duration of atrial fibrillation (AF) is critical for its safe management. Recent studies suggested that copeptin, carbohydrate antigen-125 (CA-125), galectin-3 and growth...

Oxidized-CaMKII and O-GlcNAcylation cause increased atrial fibrillation in diabetic mice by distinct mechanisms.

Nov 09, 2020

Diabetes mellitus (DM) and atrial fibrillation (AF) are major unsolved public health problems, and diabetes is an independent risk factor for AF. However, the mechanism(s) underlying this clinical ass...

Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.

Nov 05, 2020

Incidence rates for lower extremity deep vein thrombosis (DVT) range from 88 to 112 per 100 000 person-years and increase with age. Rates of recurrent VTE range from 20% to 36% during the 10 years a...

Lessons Learned: Using the Caprini Risk Assessment Model to Provide Safe and Efficacious Thromboprophylaxis Following Hip and Knee Arthroplasty.

Nov 05, 2020

Two of the more common potential complications after arthroplasty are venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolus (PE), and excess bleeding. Appropria...

Prevalence and incidence of adverse events with catheter ablation for adults with Wolff-Parkinson-White syndrome: a systematic review protocol.

Nov 05, 2020

The objective of this review is to synthesize the best available evidence to determine the prevalence and incidence of adverse events in patients with Wolff-Parkinson-White syndrome who have undergone...

Ceramides and Ceramide Scores: Clinical Applications for Cardiometabolic Risk Stratification.

Nov 05, 2020

Ceramides are bioactive lipids that have an important role in many cellular functions such as apoptosis and inflammation. During the past decade emerging clinical data have shown that ceramides are no...