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Cardiology General

An Observation of Racial and Gender Disparities in Congestive Heart Failure Admissions Using the National Inpatient Sample.

Nov 19, 2020

Background Congestive heart failure (CHF) is a frequent cause of inpatient admissions in the United States. The purpose of this study was to analyze the racial and gender disparities that occur in CHF...

A Heparin based dual ratiometric sensor for Thrombin.

Nov 19, 2020

Thrombin is an important enzyme that plays a pivotal role in the blood clotting pathways. An imbalance in the activity of this enzyme is clinically known to be associated with various diseases, such a...

Kanglexin, a new anthraquinone compound, attenuates lipid accumulation by activating the AMPK/SREBP-2/PCSK9/LDLR signalling pathway.

Nov 19, 2020

Hyperlipidaemia is one of the major risk factors for atherosclerosis, coronary heart disease, stroke and diabetes. In the present study, we synthesized a new anthraquinone compound, 1,8-dihydroxy-3-su...

Circulating Amyloid Beta 1-40 Is Associated with Increased Rate of Progression of Atherosclerosis in Menopause: A Prospective Cohort Study.

Nov 19, 2020

 Accumulating evidence suggests that circulating amyloidβ 1-40 (Αβ1-40), a proatherogenic aging peptide, may serve as a novel biomarker in cardiovascular disease (CVD). We aimed to explore the ro...

Antithrombotic therapy and the risk of new-onset dementia in elderly patients with atrial fibrillation.

Nov 19, 2020

Atrial fibrillation (AF) is associated with an increased risk of dementia. Little is known about the relationship of antithrombotic therapy and the risk of dementia in patients with AF without clinica...

Effectiveness and safety of same day discharge after left atrial appendage closure under moderate conscious sedation.

Nov 19, 2020

Left atrial appendage occlusion (LAAO) using Watchman device has become a world-wide, well-established therapeutic alternative to chronic systemic oral anticoagulation in patient who are at high-risk ...

Lessons of the month: A forgotten classic: Delayed diagnosis of mitral stenosis presenting initially as Ortner's syndrome.

Nov 19, 2020

We present a rare case of delayed diagnosis of mitral stenosis, initially presenting with hoarseness in her voice due to left recurrent laryngeal nerve (LRLN) compression. A 60-year-old woman presente...

Outcomes of long-term anticoagulant treatment for the secondary prophylaxis of splanchnic venous thrombosis.

Nov 16, 2020

Splanchnic vein thrombosis (SVT) is an uncommon but potentially life-threatening disease usually related to different underlying clinical conditions. The risk of SVT recurrences is high over time in p...

Thrombosis in Hospitalized Patients with Viral Respiratory Infections versus COVID-19.

Nov 16, 2020

Thrombosis is a prominent feature of the novel Coronavirus disease 2019 (COVID-19). The incidence of thrombosis during hospitalization for non-COVID-19 viral respiratory infections is uncertain. We ev...

Lower limb deep vein thrombosis in COVID-19 patients admitted to intermediate care respiratory units.

Nov 16, 2020

COVID-19 has been associated with an increased risk of thrombotic events; however, the reported incidence of deep vein thrombosis varies depending, at least in part, on the severity of the disease. Ai...

Intensity of Guideline-Directed Medical Therapy for Coronary Heart Disease and Ischemic Heart Failure Outcomes.

Nov 16, 2020

The impact of guideline-directed medical therapy for coronary heart disease in those with hospitalized acute heart failure is unknown.We studied guideline-directed medical therapies for coronary disea...

Multiple interventions following an acute coronary syndrome event increase uptake into cardiac rehabilitation.

Nov 16, 2020

Cardiac rehabilitation (CR) improves morbidity and mortality. Uptake varies for patients following acute coronary syndrome (ACS). Entry into CR is often dependent on the management strategy received, ...

Percutaneous coronary intervention with drug eluting stents versus coronary artery bypass graft surgery in patients with advanced chronic kidney disease: A systematic review and meta-analysis.

Nov 16, 2020

Το perform a systematic review and meta-analysis of the available literature comparing safety and efficacy outcomes between percutaneous coronary intervention (PCI) with drug-eluting stents (DES) an...

Trends and diagnostic value of D-dimer levels in patients hospitalized with coronavirus disease 2019.

Nov 16, 2020

Coronavirus disease 2019 (COVID-19) has been associated with increased incidence of venous thromboembolic events (VTE) as well as mortality. D-dimer is a marker of fibrinolysis and has been used as a ...

Clinical Presentation and Risk Factors for Poor Outcomes Among Adult Patients With Posterior Reversible Encephalopathy Syndrome: A Retrospective Cohort Study.

Nov 16, 2020

Posterior reversible encephalopathy syndrome (PRES) is an acute neurological condition with unknown global incidence, variable clinical presentation, and prognosis.To describe a cohort of patients wit...

Magnetic Resonance Vessel Wall Imaging in Central Nervous System Vasculitides: A Case Series.

Nov 16, 2020

We aim to report 3 cases of central nervous system (CNS) vasculitides, in which high-resolution magnetic resonance vessel wall imaging (HR-VWI) findings were instrumental in the diagnosis and manageme...

High glucose load and endotoxemia among overweight and obese Arab women with and without diabetes: An observational study.

Nov 16, 2020

Dietary intake influences gut microbiota activity. Nevertheless, there is a lack of evidence available that illustrates the acute effects of high glucose meal on metabolic endotoxemia. The present stu...

Population pharmacokinetics and dosing optimization of metformin in Chinese patients with type 2 diabetes mellitus.

Nov 16, 2020

Approximately 35% of patients fail to attain ideal initial blood glucose control under metformin monotherapy. The objective of this observational study is to simulate the optimal protocol of metformin...

The Impact of Obesity on Risk Factors for Adverse Outcomes in Patients Undergoing Elective Posterior Lumbar Spine Fusion.

Nov 16, 2020

Retrospective case control study.To determine the influence of obesity on risk factors for adverse outcome after lumbar spine fusion (LSF).Obesity is risk factor for complications after LSF and poses ...

Effects of different positions of intravascular stent implantation in stenosed vessels on in-stent restenosis: An experimental and numerical simulation study.

Nov 16, 2020

Percutaneous coronary intervention (PCI) has been widely used in the treatment of atherosclerosis, while in-stent restenosis (ISR) has not been completely resolved. Studies have shown that changes in ...