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Cardiology General

Midlevel visual deficits after strokes involving area human V4.

Dec 10, 2020

We present the results of 51 stroke patients with free central visual fields of which about half suffer from clear deficits of midlevel vision undetected by standard clinical tests. These patients yie...

Elevated White Blood Cell Count Resultant Atherogenesis is Associated With Panoramic-Imaged Carotid Plaque.

Dec 10, 2020

Atherosclerotic plaques develop as a result of a low-grade, chronic, systemic inflammatory response to the injury of endothelial cells arising from lipid deposition within the intima. Increased white ...

Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes.

Dec 10, 2020

The adult mammalian heart consists of mononuclear and binuclear cardiomyocytes (CMs) with various ploidies. However, it remains unclear whether a variation in ploidy or number of nuclei is associated ...

In patients undergoing coronary artery bypass grafting, is endoscopic harvesting superior to open radial artery harvesting?

Dec 10, 2020

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was 'In patients undergoing coronary artery bypass grafting, is endoscopic radial artery...

Kidney Outcomes and Hypertension in Survivors of Wilms Tumor: A Prospective Cohort Study.

Dec 10, 2020

Supported by a Pilot Grant from the Children's Hospital of Philadelphia Center for Pediatric Clinical Effectiveness (to D.C.). D.C. is also supported by the NIH/NIDDK (K23 DK125670). G.T. was supporte...

COVID-19 in Renal Transplant Recipients: Case Series and a Brief Review of Current Evidence.

Dec 10, 2020

By April 26, 2020, infections related to coronavirus disease 2019 (COVID-19) affected people from 210 countries and caused 203,818 reported deaths worldwide. A few studies discussed the outcome of COV...

Reducing salt intake by urine chloride self-measurement in non-compliant patients with chronic kidney disease followed in nephrology clinics: a randomized trial.

Dec 10, 2020

Adherence to low salt diets and control of hypertension remain unmet clinical needs in chronic kidney disease (CKD) patients.We performed a 6-month multicentre randomized trial in non-compliant patien...

Temperature dependent aggregation mechanism and pathway of lysozyme: By all atom and coarse grained molecular dynamics simulation.

Dec 10, 2020

Aggregation of protein causes various diseases including Alzheimer's disease, Parkinson's disease, and type II diabetes. It was found that aggregation of protein depends on many factors like temperatu...

A model integrating donor gene polymorphisms predicts fibrosis after liver transplantation.

Dec 10, 2020

Post-transplant liver fibrosis (PTLF) is a common and severe complication in liver recipients. In this study, we assessed the impact of donor liver genetics on the development of PTLF. A total of 232 ...

[Current review of factors in the stem cell donor that influence the regenerative potential of adipose tissue-derived stem cells].

Dec 10, 2020

Regenerative therapies like cell-assisted lipotransfer or preclinical experimental studies use adipose tissue-derived stem cells (ASCs) as the main therapeutic agent. But there are also factors depend...

The 1316T>C missenses mutation in MTHFR contributes to MTHFR deficiency by targeting MTHFR to proteasome degradation.

Dec 10, 2020

5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare hereditary disease characterized by defects in folate and homocysteine metabolism. Individuals with inherited gene mutations have...

Tanshinone IIA attenuates atherosclerosis via inhibiting NLRP3 inflammasome activation.

Dec 10, 2020

Tanshinone IIA (Tan IIA) possesses potent anti-atherogenic function, however, the underlying pharmacological mechanism remains incompletely understood. Previous studies suggest that oxidized LDL (oxLD...

Atherosclerosis is associated with poorer outcome in non-occlusive mesenteric ischemia.

Dec 10, 2020

To evaluate whether abdominal atherosclerosis was associated with poorer outcome in a single-centre cohort of patients suffering from nonocclusive mesenteric ischemia (NOMI).From January 2009 to Decem...

[2020 ESC guidelines on atrial fibrillation : Summary of the most relevant recommendations and innovations].

Dec 10, 2020

The new guidelines for the diagnosis and management of atrial fibrillation (AF) were published by the European Society of Cardiology (ESC) in collaboration with the European Association for Cardio-Tho...

Association of digoxin therapy with case fatality rate in acute pulmonary embolism.

Dec 10, 2020

Despite wide usage of digoxin for various diseases in cardiology practice, its benefit is controversial and moreover it had been associated with unfavorable outcomes in some previous studies. The aim ...

Metabolic Phenotyping Refines CVD Risk in Young Adults

Dec 08, 2020

Although cardiovascular disease (CVD) metrics define risk in individuals aged over 40, CVD's most initial lesions appear well before this age. Despite the role of metabolism in CVD predecessors, the s...

HIV Antivirals Affect Endothelial Activation

Dec 08, 2020

HIV patients on effective antiretroviral therapy are often at an increased risk of cardiovascular complications, possibly attributed to off-target drug effects. Previous studies have associated antire...

Underlying Cancer Diagnosed by Bleeding in Patients having AF

Dec 08, 2020

Bleeding in patients occurs frequently when treated with oral anticoagulant therapy for atrial fibrillation (AF); this might be the first manifestation of underlying cancer. This study aimed to invest...

Translatable Periprocedural Hydrogen Sulfide Therapy

Dec 08, 2020

The rates of failure after revascularization surgery are high for both vein grafts (VG) and in arterial interventions. One approach to improve outcomes is the upregulation of the gaseous transmitter�...

Colchicine in Patients with ACS

Dec 08, 2020

Inflammation plays a major role in the complications and clinical manifestations of acute coronary syndrome (ACS). Colchicine is an often used treatment for gout, and has recently emerged as a therape...