Dec 21, 2020

In clinical practice, there is evidence of failure to prescribe evidence-based therapies for patients at high cardiovascular risk. However, in Brazil, data on 1-year outcomes of these patients remain ...

Dec 21, 2020

Subcortical aphasia develops as a result of damage to subcortical brain areas without loss of cortical functions. Although earlier voxel-based lesion-symptom mapping (VLSM) studies have shown possible...

Dec 21, 2020

Circadian rhythms follow a 24 h day and night cycle, regulate vital physiological processes, and are especially relevant to cardiovascular growth, renewal, repair, and remodeling. A recent flurry of ...

Dec 21, 2020

The optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) is under controversial. The aim of the present systematic review and meta-analysis was to evalua...

Dec 21, 2020

Partial lamellar sclerouvectomy was designed more than 30 years ago by Jerry and Carol Shields, in order to remove melanomas that involved the ciliary body and/or the choroid, while leaving intact the...

Dec 21, 2020

Tropomyosin (TPM), an actin-binding protein widely expressed across different cell types, is primarily involved in cellular contractile processes. We investigated whether TPM3 physically and functiona...

Dec 21, 2020

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the Western world, and it is closely associated to obesity, type 2 diabetes mellitus, and dyslipidemia. Medicinal cannabis...

Dec 21, 2020

Obesity, lipodystrophy, diabetes, and hypertension collectively constitute the main features of Metabolic Syndrome (MetS), together with insulin resistance (IR), which is considered as a defining elem...

Dec 21, 2020

Transcranial surgery(TCS) for pituitary adenoma(PA) is mostly reserved for lesions with widespread extensions. We sought to analyse the intraoperative challenges, morbidity and the factors associated ...

Dec 21, 2020

Atherosclerosis, a chronic progressive inflammatory condition characterized by the formation of lipid-laden lesions in arterial walls, is associated with substantial morbidity (including ischaemic str...

Dec 21, 2020

Salidroside is a kind of phenylethanoid glycoside and widespread in the plants from Rhodiola and Ligustrum species. Our previous study has reported that salidroside can prevent atherosclerosis progres...

Dec 21, 2020

Intestinal flora plays a major role in cardiovascular diseases, like atherosclerosis (AS). Ginkgolide B (GB), a natural substance extracted from Ginkgo biloba L., is recently acknowledged as a potenti...

Dec 18, 2020

Maintenance treatment draws out progression-free endurance (PFS) in patients with recently analyzed different myeloma (NDMM) not going through autologous stem cell transplantation (ASCT) is limited to...

Dec 18, 2020

Neuromuscular blockade (NMB) agents are often used to control shivering during temperature management that is followed by cardiac arrest. In this study, we hypothesized that early, continuous NMB woul...

Dec 18, 2020

Myotonic dystrophy type 1 involves cardiac conduction disorders. Cardiac conduction disease might cause sudden death or fatal arrhythmias in patients suffering from myotonic dystrophy type 1. This st...

Dec 18, 2020

The objectives of this study were to  compare and investigate the incidences and risks of venous thromboembolism (VTE) between the two groups of patients with community-acquired pneumonia (CAP) and C...

Dec 18, 2020

The aim of this study was to outline spatial and temporal dynamics of vascular smooth muscle cell (SMC) transcriptomic changes during aortic aneurysm development in Marfan syndrome (MFS). Single-cell...

Dec 18, 2020

Heavy consumption of alcohol has a deep rooted association with hypertension. However, whether moderate alcohol consumption has a similar effect or not remains unknown. This relationship is not well�...

Dec 18, 2020

Patients with permanent atrial fibrillation have quality of life, exercise capacity, and poor outcomes even on optimal anticoagulation. Based on the observational and mechanistic data, we tested wheth...

Dec 18, 2020

Despite well-documented cardiovascular disparities between racial groups, within-race determinants of cardiovascular health remain understudied. The objective of this study was to examine whether neig...