Dec 24, 2020

Severe pneumonia is a common compilation of COVID-19. Several studies have supported the efficacy of convalescent plasma treatment to improve the clinical outcomes in patients with COVID-19. But wheth...

Dec 23, 2020

As COVID-19 continues to spread, medical institutes across the world are working towards strategies to prevent the disease.  The current strategies, however, are limited to non-pharmacologic interven...

Dec 23, 2020

Frequent exacerbations are common in patients with bronchiectasis, which are thought to be related to neutrophilic inflammation. Bronchiectasis at baseline is characterized by the increased activity a...

Dec 23, 2020

The World Health Organization has recommended mortality trials for four repurposed antiviral drugs: remdesivir, lopinavir, hydroxychloroquine, and interferon beta-1a. However, the efficacy of all thes...

Dec 23, 2020

Individuals, mainly children, who have been hospitalized for severe anemia are at a higher risk of hospital readmission and death due to malaria. No prevention strategies are available to address this...

Dec 23, 2020

A polypill is a medication drug that comprises multiple active pharmaceutical ingredients. A polypill consisting of statins, blood pressure-lowering drugs, and aspirin is known to reduce the risk of c...

Dec 23, 2020

Recent studies have shown that omecamtiv, a selective cardiac myosin activator, can improve cardiac function in patients with heart failure and a reduced ejection fraction. However, the effect of omec...

Dec 23, 2020

In patients with refractory hypercholesterolemia who have high low-density lipoprotein (LDL) cholesterol levels after lipid-lowering therapies at maximum doses are at a higher risk of atherosclerosis....

Dec 23, 2020

Pericarditis is a cardiovascular condition characterized by the inflammation of the pericardium, resulting in sharp chest pain. Interleukin-1 is a mediator of recurrent pericarditis, but its efficacy ...

Dec 22, 2020

While several medical practices are considering catheter ablation as the initial treatment for atrial fibrillation (AF), guidelines suggest that a trial of one or more antiarrhythmic drugs should be c...

Dec 22, 2020

Sodium-glucose cotransporter 2 (SGLT2) inhibitors are given as the first-line treatment for type-2 diabetes and the prevention of cardiovascular events. However, the efficacy of SGLT2 inhibitors like ...

Dec 22, 2020

In patients with stable heart failure, sodium-glucose cotransporter 2 (SGLT2) inhibitors can alleviate the risk of heart failure or death due to cardiovascular causes. However, the effectiveness of SG...

Dec 22, 2020

Catheter ablation is proven to be a more effective therapy for symptomatic paroxysmal atrial fibrillation (AF) non-responsive to the medication when compared with antiarrhythmic drug therapy. However,...

Dec 22, 2020

High blood pressure or hypertension is a prevalent health problem found in almost 25% of the global population. If uncontrolled, high blood pressure can increase the risk of morbidity and mortality. T...

Dec 22, 2020

While endovascular treatments for peripheral artery disease (PAD) are on the rise, their safety, efficacy, and durability remain questionable. Hence, lower limb revascularization surgeries are preferr...

Dec 22, 2020

Several controlled trials have suggested that high consumption of red meat could be associated with a higher risk of mortality and chronic diseases. But how exactly does it impact the risk of coronary...

Dec 21, 2020

Spontaneous subclavian vein thrombosis (Paget Schroetter Syndrome, PSS) has been attributed to venous compression at the thoracic outlet and traditionally diagnosed on basis of venography. Intravascul...

Dec 21, 2020

Thrombophilia conditions are associated with an increased risk of venous thromboembolism. Elevated plasma levels of factor VIII (> 150 IU per deciliter) increase the risk of venous thrombosis. The ...

Dec 21, 2020

Non-alcoholic fatty liver disease (NAFLD) is an emerging and threatening pathological condition, ranging from fatty liver (FL) to chronic steatohepatitis (NASH), liver cirrhosis, and eventually to hep...

Dec 21, 2020

Sodium is an essential mineral and nutrient used in dietary practices across the world and is important to maintain proper blood volume and blood pressure. A high sodium diet is associated with increa...