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Cardiology General

Multidisciplinary approach to the complex treatment for non-cirrhotic portal hypertension - case-report-based discussion.

Jan 14, 2021

Non-cirrhotic portal vein thrombosis (PVT) in patients with antiphospholipid syndrome (APS) is a rare complication, and the management has to be determined individually based on the extent and severit...

Pulmonary thromboembolism in coronavirus disease 2019 patients undergoing thromboprophylaxis.

Jan 14, 2021

We aimed to investigate the prevalence of pulmonary thromboembolism (PTE) and its association with clinical variables in a cohort of hospitalized coronavirus disease 2019 (COVID-19) patients receiving...

Inhibition of TGFβ-activated kinase 1 promotes inflammation-resolving microglial/macrophage responses and recovery after stroke in ovariectomized female mice.

Jan 14, 2021

TGFβ-activated kinase 1 (TAK1) is a master regulator that drives multiple cell death and proinflammatory signaling pathways, making it a promising therapeutic target to treat ischemic stroke. However...

An fMRI, DTI and Neurophysiological Examination of Atypical Organization of Motor Cortex in Ipsilesional Hemisphere Following Post-Stroke Recovery.

Jan 14, 2021

We report a 61-year-old woman who developed left hemiparesis following a right frontal stroke. She underwent rehabilitation and regained function of the left side of her body. Three years after her fi...

Influence of Including Patients with Premorbid Disability in Acute Stroke Trials: The HeadPoST Experience.

Jan 14, 2021

Patients with premorbid functional impairment are generally excluded from acute stroke trials. We aimed to determine the impact of including such patients in the Head Positioning in acute Stroke Trial...

Efficacy and safety of the glucagon-like peptide-1 receptor agonist oral semaglutide in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

Jan 14, 2021

To evaluate the efficacy and safety of the glucagon-like peptide-1 (GLP-1) receptor agonist (RA) oral semaglutide in the treatment of type 2 diabetes mellitus (T2DM) patients.Randomized controlled tri...

Characterizing regional myofiber damage post acute myocardial infarction using global optimization.

Jan 14, 2021

Medical imaging derived cardiac biomechanical models offer a wealth of new information to be used in diagnosis and prognosis of cardiovascular disease. A noteworthy feature of such models is the abili...

STEM CELLS FOR TREATMENT OF CARDIOVASCULAR DISEASES: AN UMBRELLA REVIEW OF RANDOMIZED CONTROLLED TRIALS.

Jan 14, 2021

Stem cells are a promising therapy for various medical conditions. The literature regarding their adoption for the clinical care of cardiovascular diseases (CVD) is still conflicting. Therefore, our a...

Effects of tart cherry and its metabolites on aging and inflammatory conditions: Efficacy and possible mechanisms.

Jan 14, 2021

Inflammation is an underlying cause of or a contributing factor to a number of chronic conditions, including hypertension, insulin resistance, arthritis, and cognitive disorders. A chronic inflammator...

Predictors of hypertension detection in English general practices: a cross sectional study.

Jan 14, 2021

Worldwide, high systolic blood pressure is the leading risk factor for deaths and disability-adjusted life-years but has been historically under-detected. This study aimed to quantify differences betw...

Olanzapine-induced insulin resistance may occur via attenuation of central K channel-activation.

Jan 14, 2021

Antipsychotic use is associated with an increased risk of type 2 diabetes. Recent work suggests antipsychotics can induce insulin resistance immediately and independently of weight gain, and that this...

Ameliorative effects of endurance training and Matricaria chamomilla flowers hydroethanolic extract on cognitive deficit in type 2 diabetes rats.

Jan 14, 2021

Diabetes mellitus is mainly associated with degeneration of the central nervous system, which eventually leads to cognitive deficit. Although some studies suggest that exercise can improve the cogniti...

Silk fibroin/poly-(L-lactide-co-caprolactone) nanofiber scaffolds loaded with Huangbai Liniment to accelerate diabetic wound healing.

Jan 14, 2021

Diabetic infection is a long-term complication difficult to cure. The skin of diabetic patients is prone to damage, the healing is slow after the injury, and the wound occurs repeatedly. Therefore, th...

Genetic Risk Score to Identify Risk of Venous Thromboembolism in Patients with Cardiometabolic Disease.

Jan 14, 2021

- Venous thromboembolism (VTE) is a major cause of cardiovascular morbidity and mortality with a known genetic contribution. We tested the performance of a genetic risk score (GRS) for its ability to...

Deletion of bone marrow myeloperoxidase attenuates chronic kidney disease accelerated atherosclerosis.

Jan 14, 2021

Increased myeloperoxidase (MPO) expression and activity are associated with atherosclerotic disease in patients with chronic kidney disease (CKD). However, the causal relationship between MPO and the ...

Effect of oxytocin on lipid accumulation under inflammatory conditions in human macrophages.

Jan 14, 2021

Oxytocin (OT) is a neuropeptide hormone secreted by the posterior pituitary gland. Deficits in OT action have been observed in patients with behavioral and mood disorders, some of which correlate with...

Hyperoxia-induced miR-342-5p downregulation exacerbates neonatal bronchopulmonary dysplasia via the Raf1 regulator Spred3.

Jan 14, 2021

Bronchopulmonary dysplasia (BPD) is the most prevalent chronic pediatric lung disease and is linked to the development of chronic obstructive pulmonary disease. MicroRNA-based regulation of type II al...

Dog-Shaped Balloon

Jan 13, 2021

“Just so you’ll be relaxed, we’re doing your heart catherization "Just so you’ll be relaxed, we’re doing your heart catherization with a dog-shaped balloon." ...

"The Timing of Venous Thromboembolism in Ovarian Cancer patients. A Nationwide Danish Cohort Study".

Jan 11, 2021

Venous thromboembolism (VTE) is associated with excess mortality and morbidity in cancer, and is influenced by patient-, tumor- and treatment-related factors. We aimed to investigate the impact of suc...

Cumulative incidence of venous thromboembolism in patients with advanced cancer in prospective observational study.

Jan 11, 2021

Venous thromboembolism (VTE) is frequently observed in patients with advanced cancer. The objective of this prospective observational study was to estimate, based on intensive screening, using compute...