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Cardiology General

Hysterectomy and ischemic heart disease: An observational study using propensity score methods in NHANES 2007-2018.

May 20, 2021

The association between hysterectomy and cardiovascular disease (CVD) remains controversial and research focusing on different types of CVD, especially ischemic heart disease, is scant.This observatio...

Meta-analysis of randomized clinical trials comparing PCSK9 monoclonal antibody versus ezetimibe/placebo in patients at high cardiovascular risk.

May 20, 2021

Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies (PCSK9 mAbs) reduce circulating low-density lipoprotein cholesterol (LDL-C) by controlling the expression of LDL-receptor on the sur...

Activated pathogenic Th17 lymphocytes induce hypertension following high-fructose intake in Dahl salt-sensitive (SS) but not Dahl salt-resistant (SR) rats.

May 20, 2021

High-salt or high-fructose intakes are risk factors for hypertension via oxidative stress and inflammation. T helper (Th)17 lymphocytes play an important role in the development of hypertension. We te...

Noncatalytic function of PI3Kγ drives smooth muscle cell proliferation after arterial damage.

May 20, 2021

Arterial remodeling in hypertension and intimal hyperplasia involves inflammation and disrupted flow, both of which contribute to smooth muscle cell dedifferentiation and proliferation. In this contex...

Surgically induced deficiency of sex hormones modulates coronary vasodilation by estradiol in hypertension.

May 20, 2021

The effect of oestrogen in hormonal dysfunction is not clear, especially in the coronary vascular bed. This study aimed at estradiol action (E2) in the coronary vascular bed from sham-operated and gon...

The effect of diet change and insulin dysregulation on the fecal microbiome of ponies.

May 20, 2021

The equine microbiome can change in response to dietary alteration and might play a role in insulin dysregulation. The aim of this study was to determine the effect of adding pasture to a hay diet on ...

Network analysis reveals important genes in human placenta.

May 20, 2021

To determine which genes are important in placenta by network analysis.Placenta expressing genes were screened from RNA-Seq data. Protein-protein interaction data were downloaded from STRING (v11.0) d...

Effect of Vitamin D status on QTc interval in type 2 diabetes mellitus.

May 20, 2021

Diabetes mellitus (DM) is associated with autonomic neuropathy and metabolic abnormalities. These predispose the patients to prolongation of QTc and risk of arrhythmias and sudden cardiac death. Vitam...

Usefulness of Stress Echocardiography in Assessment of Dynamic Left Ventricular Obstructions: Case Series and Review of the Literature.

May 20, 2021

Dynamic left ventricular outflow tract obstruction (DLVOTO) or midcavity obstruction in patients with structurally normal hearts is not uncommon in routine clinical practice and can cause significant ...

Cell-specific and athero-protective roles for RIPK3 in a murine model of atherosclerosis.

May 20, 2021

Receptor-interacting protein kinase 3 (RIPK3) was recently implicated in promoting atherosclerosis progression through a proposed role in macrophage necroptosis. However, RIPK3 has been connected to n...

Ligustrum Robustum Alleviates Atherosclerosis by Decreasing Serum TMAO, Modulating Gut Microbiota and Decreasing Bile acid and Cholesterol Absorption in Mice.

May 20, 2021

Atherosclerosis (AS) is closely related to gut microbiota. Our previous studies demonstrated that Ligustrum robustum (LR), a flavonoid-rich tea like plant, could mitigate several AS-related risk facto...

Antithrombotic treatment management in low stroke risk patients undergoing cardioversion of atrial fibrillation <48 h duration: results of an EHRA survey.

May 20, 2021

Data supporting the safety of cardioversion (CV) of atrial fibrillation (AF) without anticoagulation in patients with AF duration <48 h are scarce. Observational studies suggest that the risk of ...

Obstructive sleep apnoea testing and management in atrial fibrillation patients: a joint survey by the European Heart Rhythm Association (EHRA) and the Association of Cardiovascular Nurses and Allied Professions (ACNAP).

May 20, 2021

Obstructive sleep apnoea (OSA) is highly prevalent in atrial fibrillation (AF) patients and associated with reduced response to rhythm control strategies. However, there is no practical guidance on te...

Conference Highlights: ACC.21

May 18, 2021

New research was presented at ACC.21, the virtual annual American College of Cardiology Scientific Sessions, from May 15-17. The features below highlight some of the studies that emerged from the conf...

Carboplatin-Paclitaxel in triple-negative metastatic breast cancer during pregnancy with neoplastic thrombosis.

May 17, 2021

The treatment of breast cancer diagnosed during pregnancy is a challenging situation for the patient, family and healthcare providers. Here we describe the case of a 35-year-old woman diagnosed with a...

Portal Vein Thrombosis may Be More Strongly Associated With Islet Infusion Than Extreme Thrombocytosis After Total Pancreatectomy With Islet Autotransplantation.

May 17, 2021

Total pancreatectomy with islet autotransplantation (TPIAT) involves pancreatectomy, splenectomy, and reinjection of the patient's pancreatic islets into the portal vein. This process triggers a local...

Traumatic cerebral dural sinus vein thrombosis/stenosis in pediatric patients-is anticoagulation necessary?

May 17, 2021

Cerebral dural vein thrombosis/stenosis (CDVT/S) is a condition that affects the venous drainage of the brain. Risk factors and causes associated with CDVT/S include systemic risk factors that cause h...

SpES: A new portable device for objective assessment of hypertonia in clinical practice.

May 17, 2021

Spasticity is a motor disorder that affects millions around the world. It is a particular type of hypertonia characterized by the speed-dependent increase of the muscle stretch reflex, where its corre...

Sleep architectural dysfunction and undiagnosed obstructive sleep apnea after chronic ischemic stroke.

May 17, 2021

Sleep-wake dysfunction is bidirectionally associated with the incidence and evolution of acute stroke. It remains unclear whether sleep disturbances are transient post-stroke or are potentially enduri...

cGMP and mitochondrial K channels - Compartmentalized but closely connected in cardioprotection.

May 17, 2021

The 3',5'-cyclic guanosine monophosphate (cGMP) pathway triggers cytoprotective responses and improves cardiomyocyte survival during myocardial ischemia and reperfusion (I/R) injury. These beneficial ...