Nov 27, 2023

There are nearly 65 million people with chronic heart failure (CHF) globally, with no treatment directed at the pathologic cause of the disease, the loss of functioning cardiomyocytes. We have an allo...

Nov 27, 2023

The diagnosis of acute myocardial infarction is based on ECG abnormalities besides to chest pain and dyspnea. It is caused by myocardial hypoperfusion, in most patients due to severe coronary artery n...

Nov 27, 2023

A deadly embrace occurs between cancer and chronic kidney disease. The estimation of kidney function in cancer patients is of utmost interest due to its direct impact on chemotherapy dosing, selection...

Nov 27, 2023

Kidney cancer is one of the most common cancers globally, ranking 9th and 14th among men and women, respectively. Advances in diagnostic techniques have enabled earlier and potentially less invasive i...

Nov 27, 2023

The aim of this study was to determine the cost-effectiveness of remote patient monitoring (RPM) with First Nations peoples living with diabetes. This study was set at the Goondir Health Service (GHS)...

Nov 27, 2023

To investigate possible targets of Ligustrum lucidum and its anti-inflammatory mechanism. Core targets were screened by the established networks of component target and potential protein interaction, ...

Nov 27, 2023

To analyze anti-depression mechanism of Baihe Zhimu decoction (BZD) based on network pharmacology method, which provides reference for the development of new drugs and the clinical application of clas...

Nov 27, 2023

Breast cancer and cardiovascular diseases (CVD) represent significant global health challenges, with CVD being the leading cause of mortality and breast cancer, showing a complex pattern of incidence ...

Nov 20, 2023

Bacteremia caused by Serratia rubidaea is seldom mentioned in comparison with other Enterobacteriaceae species. It primarily affects immunocompromised patients undergoing invasive procedures. Furtherm...

Nov 20, 2023

To externally validate a recently developed cardiovascular disease (CVD) risk model for Omanis with type 2 diabetes mellitus (T2DM).Retrospective cohort study.Nine primary care centres in Muscat Gover...

Nov 20, 2023

Low-risk venous thromboembolism (VTE) patients are advised to be discharged from the emergency department (ED) on direct oral anticoagulants (DOACs) treatment. There is no data on whether this recomme...

Nov 20, 2023

Objective To investigate the effect of adipocytokine Apelin-13 (AP13) on mitochondrial autophagy in myocardial ischemia reperfusion injury (MIRI) and its mechanism. Methods MIRI model was established ...

Nov 20, 2023

CC-115, a dual mTORC1/2 and DNA-PK inhibitor, has promising antitumour activity when combined with androgen receptor (AR) inhibition in pre-clinical models.Phase 1b multicentre trial evaluating enzalu...

Nov 20, 2023

Changes in skeletal muscle mass and quality are associated with type 2 Diabetes (T2D) and its complications. We evaluated the prevalence of sarcopenia in patients with T2D and its association with var...

Nov 20, 2023

Glucagon-like peptide 1 (GLP-1) is produced by the L subtype of enteroendocrine cells (EECs). Patients with type 2 diabetes (T2D) exhibit reduced incretin effect, but the pathophysiology and functiona...

Nov 20, 2023

Macrophages are a class of innate immune cells with strong plasticity. They can polarize into different phenotypes, serving with various functions, such as phagocytosis and chemotaxis, which is involv...

Nov 20, 2023

Electrocardiographic findings and arrhythmias are common in cardiomyopathies. Both may be an early indication of a specific diagnosis or may occur due to myocardial fibrosis and/or reduced contractil...

Nov 20, 2023

Current guidelines recommend a rhythm control strategy in patients with symptomatic atrial fibrillation (AF) while catheter ablation has been shown to be a safer and more efficacious approach than ant...

Nov 13, 2023

Guidelines developed by the American College of Cardiology/American Heart Association (ACC/AHA) recommend lipid-lowering therapies (LLTs) to reduce low-density lipoprotein cholesterol (LDL-C) and athe...

Nov 13, 2023

To investigate predictors indicating the continuous need for a knee-ankle-foot orthosis (KAFO) at 1 month after stroke onset in patients who cannot walk without a KAFO in the acute period.We enrolled ...