Jun 24, 2021

The pathological cardiac functions of ankyrin repeat domain 1 (ANKRD1) in left ventricle can directly aggravate cardiac hypertrophy (CH) and fibrosis through the activation of extracellular signal-reg...

Jun 24, 2021

After an acute myocardial infarction (MI), patients may develop posttraumatic stress disorder (PTSD). There is evidence for alterations in the hypothalamic-pituitary-adrenal axis in PTSD. An associati...

Jun 24, 2021

Iatrogenic pseudoaneurysms in scalp vessels are an uncommon complication after cranial surgery. This paper reports a case of scalp pseudoaneurysm in the superficial temporal artery (STA) after forcefu...

Jun 24, 2021

Thoracic endovascular aortic repair (TEVAR) has revolutionized the treatment of thoracic aortic aneurysms. Innovative techniques as chimney and periscope grafts can improve the outcomes of procedure. ...

Jun 24, 2021

This phase 1 study evaluated safety, pharmacokinetics (PK), maximum tolerated dose (MTD), and antitumour activity of regorafenib in paediatric patients with solid tumours.Patients (aged 6 months to &l...

Jun 24, 2021

We carried out three types of 2-hr experimental sessions with middle-aged and older adults with Type 2 diabetes in order to examine the acute effect of interrupting prolonged sitting with varying peri...

Jun 24, 2021

Diabetes mellitus is a major risk factor for microvascular disease, leading to chronic kidney injury or cardiovascular disease, but there is a tremendous proportion of patients worldwide who suffer fr...

Jun 24, 2021

Diabetes is a systemic disease in which the body cannot regulate the amount of sugar, namely glucose, in the blood. High glucose toxicity has been implicated in the dysfunction of diabetic wound heali...

Jun 24, 2021

Exposure to cadmium (Cd) via food and smoking is associated with increased risk of atherosclerotic cardiovascular disease (ASCVD). Blood and urine levels of Cd are established biomarkers of exposure. ...

Jun 24, 2021

Familial hypercholesterolemia (FH) is a genetic disease, with an autosomal codominant inheritance, predisposing to premature atherosclerotic cardiovascular disease (ASCVD). Paternal or maternal inheri...

Jun 24, 2021

Vessel centerline extraction from x-ray angiography (XRA) images is essential for vessel structure analysis in the diagnosis of coronary artery disease. However, complete and continuous centerline ext...

Jun 21, 2021

Optimizing the management of cardiovascular complications continues to be an important need in the care of patients with T2D. The therapeutic landscape for T2D has changed dramatically with the emerge...

Jun 17, 2021

Oral tranexamic acid is effective for heavy menstrual bleeding, but the thrombosis risk with this treatment is largely not studied.Using nationwide registries, we assessed associations between use of ...

Jun 17, 2021

There are 3 different types of mid-urethral sling, retropubic, transobturator and single incision performed for women with stress urinary incontinence. Prior studies comparing these three surgeries me...

Jun 17, 2021

The purpose of this study was to retrospectively evaluate the efficacy of a tranexamic acid (TXA) perioperative protocol for primary hip- and knee arthroplasty, in terms of allogenic blood transfusion...

Jun 17, 2021

We sought to evaluate Free Open Access Medical Education (FOAM), defined as online educational content available free to anyone, anywhere, at any time, by classifying the most impactful FOAM content p...

Jun 17, 2021

Disturbances of glucose metabolism can be diagnosed by an oral glucose tolerance test (OGTT) and by glycated haemoglobin (HbA1c). The aim of this study was to investigate the association between newly...

Jun 17, 2021

The characteristics and pathophysiological mechanisms involved in acute ischemic stroke in patients with COVID-19 infection have not been fully clarified. We prospectively studied the phenotypic and e...

Jun 17, 2021

Although the protective effects of alcohol consumption against future cardiovascular disease have been published, the effects of alcohol on stroke risk remain controversial.We assessed the effects of ...

Jun 17, 2021

Spontaneous coronary artery dissection (SCAD) can lead to acute coronary syndrome and sudden cardiac death, particularly in young women. Observational data show that, in SCAD patients, both percutaneo...