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Diabetes

Physical Activity, Sedentary Time and Cardiometabolic Health in Heavy Goods Vehicle Drivers: A Cross-Sectional Analysis.

Jan 24, 2022

Physical inactivity, prolonged sitting, and unhealthy dietary habits are common in Heavy Goods Vehicle (HGV) drivers. These factors increase risk of long-term health conditions.329 HGV drivers across ...

The dynamic interplay between AMPK/NFκB signaling and NLRP3 is a new therapeutic target in inflammation: Emerging role of dapagliflozin in overcoming lipopolysaccharide-mediated lung injury.

Jan 17, 2022

Acute lung injury (ALI) is one the most common causes of morbidity and mortality in critically ill patients. In this study, we examined for first time the role of dapagliflozin (DPGZ) in lipopolysacch...

Hypoxia preconditioning increases the ability of healthy but not diabetic rat-derived adipose stromal/stem cells (ASC) to improve histological lesions of streptozotocin-induced diabetic nephropathy.

Jan 17, 2022

Mesenchymal stromal cells (MSC) have demonstrated ability to improve diabetic nephropathy (DN) in experimental models, as well as by improving kidney endogenous progenitor cells proliferation and diff...

Dapagliflozin improves steatohepatitis in diabetic rats via inhibition of oxidative stress and inflammation.

Jan 10, 2022

Type-2 diabetes mellitus and NAFLD are considered as one of the greatest worldwide metabolic disorders with growing incidence. It was found that patients with T2DM have two-fold increase to develop NA...

Dispensation Patterns of Glucose-Lowering Drugs in Newly Diagnosed Type 2 Diabetes: Routine Data Analysis of Insurance Claims in Germany.

Dec 27, 2021

To describe dispensation patterns of glucose-lowering drugs in newly diagnosed type 2 diabetes in Germany.Based on claims data from four statutory health insurances (German Pharmacoepidemiological Res...

Factors influencing development of the infant microbiota: From prenatal period to early infancy.

Dec 27, 2021

The collection of bacteria, archaea, and eukarya colonizingthe gastrointestinal tract is termed the "gut microbiota."1) The microbiota offers many benefits to the host, through a range of physiologica...

Diabetes remission is modulated by branched chain amino acids according to the diet consumed: from the CORDIOPREV study.

Dec 06, 2021

BCAA plasma levels may be differentially associated with type 2 diabetes mellitus (T2DM) remission through the consumption of the Mediterranean diet (Med) and a low-fat (LF) diet.183 newly-diagnosed T...

Outcomes of anterior vs. posterior approach to single-level lumbar spinal fusion with interbody device: An analysis of the nationwide inpatient sample.

Dec 06, 2021

Interbody devices have revolutionized lumbar spinal fusion surgery by improving mechanical stability and maximizing fusion potential. Several approaches for interbody fusion exist with two of the most...

Effects of diabetes and obesity on cognitive impairment and mortality in older mexicans.

Nov 29, 2021

Diabetes is a risk factor for dementia and mortality, while obesity later in life is associated with a reduced risk. Their co-occurrence, diabesity, is common, but its association with dementia and mo...

Exploring equity in accessing diabetes management treatment: A healthcare gap analysis.

Nov 29, 2021

Healthcare inequities are often investigated empirically as associations between socio-economic characteristics and differences between observed healthcare utilisation and estimates of needs-based uti...

Stem Cell Transplantation Holds Promise for Patients With T1D

Nov 22, 2021

Current treatments for T1D place a heavy burden on patients. Every day, they must measure their blood sugar levels with multiple finger pricks or wearable continuous glucose monitors (CGMs) while also...

Is the Risk Really Shared? A Retrospective Analysis of Healthcare Costs of Patients With Type 2 Diabetes Mellitus on a Capitation Model.

Nov 22, 2021

Private managed healthcare organizations in South Africa (SA) use a capitation model of care for patients within their healthcare delivery systems for the optimal management of type 2 diabetes mellitu...

Virtual screening of dipeptidyl peptidase-4 inhibitors using quantitative structure-activity relationship-based artificial intelligence and molecular docking of hit compounds.

Nov 22, 2021

Dipeptidyl peptidase-4 (DPP-4) inhibitors are becoming an essential drug in the treatment of type 2 diabetes mellitus; however, some classes of these drugs exert side effects, including joint pain and...

Correlates of Insulin Selection as a First-Line Pharmacological Treatment for Gestational Diabetes.

Nov 15, 2021

 The aim of this study was to investigate prenatal factors associated with insulin prescription as a first-line pharmacotherapy for gestational diabetes mellitus (GDM; compared with oral antidiabeti...

[Analysis of hub genes and molecular mechanisms in non-alcoholic steatohepatitis based on the gene expression omnibus database].

Nov 15, 2021

To explore the hub genes and mechanisms in the pathological process of non-alcoholic steatohepatitis (NASH) by bioinformatics methods. Microarray datasets GSE89632 were downloaded from the Gene Expr...

ESPEN guideline on hospital nutrition.

Nov 08, 2021

In hospitals through Europe and worldwide, the practices regarding hospital diets are very heterogeneous. Hospital diets are rarely prescribed by physicians, and sometimes the choices of diets are bas...

Medication Nonadherence in Patients With Hypertension & Diabetes: A Compounding Issue

Nov 02, 2021

According to previous studies, only about one-half of patients with chronic diseases like hypertension and diabetes adhere to at least 80% of their medication regimens. It can be challenging for healt...

Efficacy and safety of imeglimin in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized clinical trials.

Nov 01, 2021

Imeglimin is a novel tetrahydrotriazine-containing drug suggested as a safe drug for glycemic management in patients with type 2 diabetes mellitus (T2DM). We aimed to 1) evaluate the efficacy of imegl...

Pharmacological treatment after acute coronary syndrome: Baseline clinical characteristics and gender differences in a population-based cohort study.

Nov 01, 2021

To describe baseline socio-demographic and clinical characteristics and drugs prescribed for secondary prevention after a first episode of ACS and to assess differences between men and women.PHC in Ca...

Sulfide-quinone oxidoreductase is required for cysteine synthesis and indispensable to mitochondrial health.

Oct 25, 2021

Mitochondrial dysfunction is related to common age-related disorders, including neurodegenerative diseases, metabolic syndrome, and carcinogenesis. Therefore, maintaining the functionality and integri...